腎尿管腫瘍の治療成績

概要

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Fifty-four cases of renal cell carcinoma, 24 cases of renal pelvic tumor, and 16 cases of ureteral tumor treated from Jan. 1963 to Dec. 1972 were followed through 1975. Five-year relative survival rates calculated by the actuarial method were 43% (standard error 8% , effective sample size 49) for renal cell carcinoma, 46% (standard error 12%, effective sample size 23) for renal pelvic tumor, and 43% (standard error 16%, effective sample size 15) for ureteral tumor. Pyrexia, anemia, increased erythrocyte sedimentation rate, positive C-reactive protein, decreased serum albumin, and elevated serum α_2-globulin were demonstrated to be factors of significantly poorer prognosis with regard to renal cell carcinoma. Local extension, the presence of the tumor in renal vein or regional lymph node, and the existence of distant metastasis also significantly affected survival rates. Patients receiving nephrectomy combined with chemotherapy and/or radiotherapy did not show significantly better survival rates than those with nephrectomy alone. Five-year relative survival rate for well differentiated carcinoma of renal pelvis and ureter was 90% (standard error 12%, effective sample size 15), as compared to 16% (standard error 8%, effective sample size 24) for poorly differentiated carcinoma. The recurrence rate of subsequent bladder tumors following surgery for the renal pelvic and ureteral tumors was 21%.
社団法人日本泌尿器科学会の論文