A Histological Analysis of T and B Cells in Periodontal Tissue Destruction
スポンサーリンク
概要
- 論文の詳細を見る
We immunohistologically examined the cell densities and distribution of T and B cells in periodontitis and analyzed their relationship in terms of periodontal tissue destruction. Specimens were labeled with monoclonal antibodies for T cells (CD3) and B cells (CD20) and developed using the double staining technique. CD3^+ cells appeared in low density infiltrates and increased gradually with the number of total infiltrates; in contrast, CD20^+ cells did not appear in small infiltrates but increased rapidly with the number of infiltrates. The number of fibroblastic cells negatively correlated with that of the total infiltrates and CD20^+ cells, but it did not correlate with the number of CD3^+ cells. These findings suggest that the T cells infiltrated into the inflamed sites at the onset and increased gradually with the development of inflammation and that B cells infiltrated later than T cells and their number increased rapidly with inflammation.
- 特定非営利活動法人日本臨床口腔病理学会の論文
著者
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EBISU Shigeyuki
Department of Restorative Dentistry and Endodontology, Osaka University Graduate School of Dentistry
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Ebisu Shigeyuki
Department Of Conservative Dentistry Osaka University Faculty Of Dentistry
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MATSUO Takashi
Department of Applied Chemistry, Graduate School of Engineering, Osaka University
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Noiri Yuichiro
Department of Restorative Dentistry and Endodontology, Osaka University
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Noiri Yuichiro
Department Of Conservative Dentistry Tokushima University School Of Dentistry
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Ebisu Shigeyuki
Department Of Conservative Dentistry Tokushima University School Of Dentistry
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Tagawa Chisato
Department of Conservative Dentistry, Tokushima University School of Dentistry
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Ozaki Kazumi
Department of Conservative Dentistry, Tokushima University School of Dentistry
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Ozaki Kazumi
Department Of Conservative Dentistry Tokushima University School Of Dentistry
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Tagawa Chisato
Department Of Conservative Dentistry Tokushima University School Of Dentistry
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Matsuo Takashi
Department Of Conservative Dentistry Tokushima University School Of Dentistry
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Matsuo Takashi
Department Of Applied Chemistry Graduate School Of Engineering Osaka University
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MATSUO Takashi
Department of Agricultural and Environmental Biology, University of Tokyo
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