Aureomycin投与がラツテの腸内菌叢に及ぼす影響について

概要

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Some microbiological studies were made on the intestinal flora of aureomycin-fed rats. Aureomycin was added to the standard mixed diet at the rate of 8 mg per cent and the rats were bred for 9 days. The numbers of four kinds of representative intestinal bacteria were counted by the use of some differential media and the following resutls were obtained : 1) The number of the E. coli group was most sensitively influenced by the administration of this antibiotic. The bacterial number decreased greatly but it increased twice abruptly during the period of administration. The number of the Aerobacter group increased and the Clostridium group also showed the same tendency.2) Isolated after the use of aureomycin, strains of the Aerobacter group showed high aureomycin-resistance, but those of the E. coli group were always sensitive to the antibiotic.All these findings indicte that the fecal microflora of rats was greatly influenced by the administration of aureomycin.
公益社団法人日本生物工学会の論文
1958-09-15