Modifying Effects of Maharishi Amrit Kalash 4 and 5 on Phagocytic and Digestive Functions of Macrophages in Male ICR Mice

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概要

• 論文の詳細を見る

• A study was carried out to examine modifying effects of Maharishi Amrit Kalash 4 (MAK 4) and Maharishi Amrit Kalashi 5 (MAK 5) on phagocytic and digestive functions of macrophages in male ICR mice. Mice at 4 week of age were divided into 3 groups : no treatment group (control), MAK 4 treated group (MAK 4 group) and MAK 5 treated group (MAK 5 group). MAK 4 and MAK 5 were given p.o. at 50 mg/kg per day (5 days/week) for 7 weeks. Phagocytic function of reticuloendothelial system evaluated by the carbon clearance was enhanced by the treatment of MAK 4 and MAK 5. Superoxide anion (O_<2->) production of peritoneal macrophages increased significantly in both MAK 4 and MAK 5 groups. The acid phosphatase activity of peritoneal macrophages increased significantly in MAK 4 group compared to the control group, but not in MAK 5 group. The activities of β-glucuronidase and lactate dehydrogenase in both MAK 4 and MAK 5 groups increased significantly when compared to the control group. These results suggest that MAK 4 and MAK 5 promote the phagocytic and digestive functions of macrophages and have a stimulatory effect on macrophages.

• 日本衛生学会の論文

著者

• TANAKA Takuji

  First Department of Pathology, Kanazawa Medical University

• Tanaka T

  Faculty Of Fisheries Hokkaido University

• Tanaka Takuji

  京都大学 農学研究科食品生物科学

• 杉浦 春雄

  岐阜薬科大学 解剖学・運動生理学研究室

• Sugiura Haruo

  Department Of Health And Physical Education Gifu Pharmaceutical University:department Of Hygiene Gif

• Inaba Ryoichi

  Department Of Hygiene Gifu University School Of Medicine

• Tada Toshiji

  Analytical Research Laboratories Fujisawa Pharmaceutical Co. Ltd.

• Sugiura H

  Department Of Hygiene Gifu University School Of Medicine

• Tanaka Takuji

  First Department Of Pathology Kanazawa Medical College

• IWATA Hirotoshi

  Department of Hygiene, Gifu University School of Medicine

• NISHIDA Hiroyuki

  Department of Health and Physical Education, Gifu Pharmaceutical University

• Iwata Hirotoshi

  Department Of Hygiene Gifu University School Of Medicine

• Nishida Hiroyuki

  岐阜薬科大学 保健体育学教室

• Inaba Ryoichi

  Deparatment Of Occupational Health Gifu Univ. Graduate School Of Medicine

• NISHIDA Hiroyuki

  Deparment of Electrical Engineering, Hiroshima University

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