Conjugated Linoleic Acid (CLA) Inhibits Fatty Acid Synthetase Activity in Vitro(Food & Nutrition Science)

スポンサーリンク

概要

• 論文の詳細を見る

• This paper describes the in vitro effect of conjugated linoleic acid (CLA) on fatty acid biosynthesis. Among the rat liver enzymes involved in fatty acid biosynthesis, fatty acid synthetase (FAS) showed the largest activity fluctuation with the types of fatty acids. Of the fatty acids, CLA was the most potent inhibitor of FAS, and the 9c, 11t-rather than the 10t, 12c-isomer showed greater inhibition. CLA also significantly lowered the incorporation of [^<14>C] -acetate into phospholipid in breast cancer cells, supporting the view that CLA inhibits fatty acid biosynthesis through the interaction with FAS.

• 社団法人日本農芸化学会の論文
• 2003-07-23

著者

• Toda Takayoshi

  中部徳洲会病院 臨床病理

• Toda Takayoshi

  鹿児島大学 連合農学研究科

• Oku Hirosuke

  Center Of Molecular Biosciences Tropical Biosphere Res. Center Univ. Of The Ryukyus

• OKU HIROSUKE

  Division of Molecular Biotechnology, Center of Molecular Bioscience, University of the Ryukyus

• IWASAKI HIRONORI

  Division of Molecular Biotechnology, Center of Molecular Bioscience, University of the Ryukyus

• TODA Takayoshi

  Department of Clinical Laboratory Medicine, School of Medicine, University of the Ryukyus Hospital

• WONGTANGTINTHARN Sawitree

  United Graduate School of Agricultural Sciences, Kagoshima University

• WONGTANGTINTHARN Sawitree

  Department of Bioscience and Biotechnology, Faculty of Agriculture, University of the Ryukyus

• Iwasaki Hironori

  Division Of Molecular Biotechnology Center Of Molecular Bioscience University Of The Ryukyus

• Oku Hirosuke

  Division Of Molecular Biotechnology Center Of Molecular Bioscience University Of The Ryukyus

• Toda Takayoshi

  Department Of Clinical Laboratory Medicine And Research Institute Of Comprehensive Medicine School O

• Oku H

  Division Of Molecular Biotechnology Center Of Molecular Bioscience University Of The Ryukyus

• Oku Hirosuke

  Division Of Molecular Biotechnology Center Of Molecular Biosciences University Of The Ryukyus

• Oku Hirosuke

  Division Of Molecular Biotechnology And Center For Molecular Bioscience University Of The Ryukyus

• Iwasaki Hironori

  Division Of Molecular Biotechnology And Center For Molecular Bioscience University Of The Ryukyus

• Oku Hirosuke

  Laboratory Of Applied Biochemistry Faculty Of Agriculture University Of The Ryukyus

• Wongtangtintharn Sawitree

  United Graduate School Of Agricultural Sciences Kagoshima University

関連論文

• 1,1-Diphenyl-2-picrylhydrazyl Radical Scavenging Activity and Tyrosinase Inhibitory Effects of Constituents of Sugarcane Molasses
• Isoprenoids of Okinawan Mangroves as Lipid Input into Estuarine Ecosystem
• Effect of Kokuto, a Non-Centrifugal Cane Sugar, on the Development of Experimental Atherosclerosis in Japanese Quail and Apolipoprotein E Deficient Mice
• Analysis of Microsatellite Instability and Loss of Heterozygosity in Human Aortic Atherosclerotic Lesions
• Effect of Branched-Chain Fatty Acids on Fatty Acid Biosynthesis of Human Breast Cancer Cells
• Conjugated Linoleic Acid (CLA) Inhibits Fatty Acid Synthetase Activity in Vitro(Food & Nutrition Science)
• Increased Cholesterol Absorption by Hyperlipidemia Atherosclerosis Prone (LAP) Japanese Quail
• Apolipoprotein A-I of Hyperlipidemia Atherosclerosis Prone (LAP) Quail : cDNA Sequence and Tissue Expression
• NADH-Dependent Inhibition of Branched-Chain Fatty Acid Synthesis in Bacillus subtilis
• Apolipoprotein A-1 of Japanese Quail: cDNA Sequence and Modulation of Tissue Expression by Cholesterol Feeding
• Selective Use of L-Valine and L-Isoleucine for the Biosynthesis of Branched-chain Fatty Acids in Rat Skin
• Chain Structure and Composition of Fatty Alcohol in the Monoester Fraction of Rat Skin Surface Lipid
• Morphological and Biochemical Evaluation of the Induction of Atherosclerosis in Japanese Quails
• Characterization and Bioavailability of Liposomes Containing a Ukon Extract
• Alcoholic liver cirrhosis complicated with torsade de pointes during plasma exchange and hemodiafiltration
• Linkage disequilibrium and haplotype analysis among four novel single-nucleotide polymorphisms in the human leukemia inhibitory factor (LIF) gene
• Association of the -381T/C promoter variation of the brain natriuretic peptide gene with low bone-mineral density and rapid postmenopausal bone loss
• Thirteen single-nucleotide polymorphisms in the human osteopontin gene identified by sequencing of the entire gene in Japanese individuals
• Linkage disequilibrium and haplotype analysis among ten single-nucleotide polymorphisms of interleukin 11 identified by sequencing of the gene
• A patient with primary biliary cirrhosis associated with autoimmune hemolytic anemia
• Effect of Dietary Cholesterol on the Activities of Key Enzymes of Cholesterol Metabolism in Hyperlipidemia- and Atherosclerosis-Prone Japanese Quail
• Lipid distribution in branching coral Montipora digitata
• Novel single nucleotide polymorphisms of the human nuclear factor kappa-B 2 gene identified by sequencing the entire gene
• Novel single nucleotide polymorphisms of the human colony-stimulating factor 2 (CSF2) gene identified by sequencing the entire gene
• Five novel single-nucleotide polymorphisms of human interferon gamma identified by sequencing the entire gene
• Lipid composition of mangrove and its relevance to salt tolerance
• Human Tyrosinase Inhibitor in Rum Distillate Wastewater
• Biosynthesis of Branched-chain Fatty Acid in Bacilli : FabD (malonyl-CoA:ACP transacylase) Is Not Essential for In Vitro Biosynthesis of Branched-chain Fatty Acids(Biochemistry & Molecular Biology)
• A True Hermaphrodite with Bilateral Ovotestes : A Case Report
• Mixed Gonadal Dysgenesis with Gonadoblastoma in a Female with Y Chromosome : Case Report
• An Autopsy Case of Malignant Lymphoma with Lyell's Syndrome
• Efficient Preparation of Liposomes Encapsulating Food Materials Using Lecithins by a Mechanochemical Method
• Detection of Epstein-Barr Virus and Human T-Cell Lymphotropic Virus Type 1 in Malignant Nodal Lymphoma, Studied in Okinawa a Subtropical Area in Japan
• Comparative Study of the Effect of Basal Diet Formulation, Dietary Fat and Cholesterol Levels on the Development of Aortic Atherosclerotic Lesions in B6.KOR-Apoeshl Mice
• Plexiform leiomyoma of the esophagus: A peculiar gross variant simulating plexiform neurofibroma
• Dietary Effects of Corn Oil, Oleic Acid, Perilla Oil, and Primrose Oil on Plasma and Hepatic Lipid Level and Atherosclerosis in Japanese Quail
• Effect of bleaching on lipid content and composition of Okinawan corals
• The Response of Serum and Hepatic Lipids and the Aortic Wall to Different Levels of Dietary Cholesterol : A Comparative Study between Hyperlipidemia-and-Atherosclerosis-Prone Quail and Commercially Available Quail
• The Occurrence of HR1b in the Venom of the Snake Okinawa Habu (Protobothrops flavoviridis)
• Characterization and Bioavailability of Liposomes Containing a Ukon Extract
• 1,1-Diphenyl-2-picrylhydrazyl Radical Scavenging Activity and Tyrosinase Inhibitory Effects of Constituents of Sugarcane Molasses
• Poorly differentiated sarcoma of the prostate cansing obstructive acute renal failure: A case report
• Epidemiological Study of Lipoprotein (a) in Okinawa
• 症例 Cerebral Mature Teratoma with Maligant Transfromation in a 52-year-old man: A Case Report
• Benign symmetric lipomatosis in a 73-year-old man: a case report with a brief review of the literature (固形腫瘍に対する遺伝子診断の確立と予後判定の精度向上)
• Benign Symmetric Lipomatosis in a 73-Year-Old Man : A Case Report with a Brief Review of the Literature
• Antioxidative Flavan-3-ol Glycosides from Stems of Rhizophora stylosa
• Effect of Peucedanum japonicum Thunb on the Expression of Obesity-Related Genes in Mice on a High-Fat Diet
• Isolation of a Thiamine-binding Protein from Rice Germ and Distribution of Similar Proteins
• Cloning and Functional Expression of Cycloartenol Synthases from Mangrove Species Rhizophora stylosa Griff. and Kandelia candel (L.) Druce
• Lipid biosynthesis from [^C]-glucose in the coral Montipora digitata
• Lipoprotein and Apoprotein Profiles of Hyperlipidemic Atherosclerosis-Prone Japanese Quail
• Effect of Dietary Cholesterol on the Activities of Key Enzymes of Cholesterol Metabolism in Hyperlipidemia- and Atherosclerosis-Prone Japanese Quail
• Effect of Peucedanum japonicum Thunb Extract on High-fat Diet-induced Obesity and Gene Expression in Mice
• Tumor specific cytotoxicity of arctigenin isolated from herbal plant Arctium lappa L.

もっと見る 閉じる

スポンサーリンク