1,1-Diphenyl-2-picrylhydrazyl Radical Scavenging Activity and Tyrosinase Inhibitory Effects of Constituents of Sugarcane Molasses
スポンサーリンク
概要
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In the course of our work into the use of cane by-products, we have studied the isolation and structural determination of bioactive compounds in sugarcane molasses. In this study, three stereo isomers of syringyl glycerol 3′-O-β-D-glucopyranoside, three stereo isomers of guaiacyl glycerol 3′-O-β-D-glucopyranoside, a syringyl glycerol 2′-O-β-D-glucopyranoside, tachioside and a 2,3-dihydro-3,5-dihydroxy-6-methyl-4-(H)-pyran-4-one (DDMP) were isolated from the 25% methanol eluate by Amberlite XAD-2 column chromatography of sugarcane molasses. The structures of these compounds were determined on the basis of spectroscopic evidence. These isolated compounds were examined for their scavenging activity against 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical species, and for their inhibitory activity against mushroom tyrosinase. All of the isolated compounds showed DPPH radical scavenging activity, while DDMP and tachioside showed mushroom tyrosinase inhibitory activity.
著者
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WADA Koji
Department of Preventive Medicine and Public Health, Kitasato University School of Medicine
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IWASAKI HIRONORI
Division of Molecular Biotechnology, Center of Molecular Bioscience, University of the Ryukyus
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TAKARA Kensaku
Department o Bioscience and Biotechnology, Faculty of Agriculture, University of the Ryukyus
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Otsuka Keiko
Department of Bioscience and Biotechnology, Faculty of Agriculture, University of the Ryukyus
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YAMASHITA Masatsugu
Research Laboratories, Taiyo Kagaku Co., Ltd.
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Otsuka Keiko
Department Of Bioscience And Biotechnology Faculty Of Agriculture University Of The Ryukyus
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