Cushings Syndrome due to Huge Adrenocortical Multinodular Hyperplasia
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概要
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A case of Cushings syndrome due to huge adrenocortial multinodular hyperplasia who was shown to be hyperresponsive to ACTH administration, unresponsive to metyrapone administration and resistant to dexamethasone high dose suppression was reported.<BR>After two years duration of his symptoms, the multinodular adrenals weighing 161 g in total were removed by bilateral adrenalectomy which abolished his symptoms. Postoperatively, plasma ACTH rose gradually to above normal levels, suggesting the presence of primary disorder in the hypothalamus-pituitary axis.
著者
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FUJII Hiroshi
Department of Hematology, Kyoto First Red Cross Hospital
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ABE Kaoru
Endocrine Division, National Cancer Center
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Otsuka Keiko
Department Of Bioscience And Biotechnology Faculty Of Agriculture University Of The Ryukyus
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Hidai Hideo
Department Of Urology Yokohama Dai-ichi Hospital
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SHIMIZU NAOKATA
Department of Medicine, Teikyo University
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Abe Kaoru
Endocrine Division National Cancer Center
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Fujii Hiroshi
Department Of Forensic Medicine Faculty Of Medicine Fukuoka University
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Fujii Hiroshi
Department Of Biochemistry Niigata University School Of Medicine
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OTSUKA KEIKO
Department of Urology, and Medicine, Yokohama City University School of Medicine
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HIDAI HIDEO
Department of Urology, and Medicine, Yokohama City University School of Medicine
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