Sjogren's Syndrome Complicated with Autoimmune Hepatitis and Antiphospholipid Antibody Syndrome
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概要
- 論文の詳細を見る
A 56-year-old Japanese female simultaneously developed thrombocytopenia, sicca symptoms, and an elevation of transaminase. Antiphospholipid antibodies were detected in her serum. The presence of anti-SS-A antibodies in the serum and sialectasis, disclosed by sialography, suggested the presence of primary Sjögrens syndrome (SjS). The laboratory data and the biopsy of the liver showed compatible findings with autoimmune hepatitis (AIH). Thrombocytopenia and liver dysfunction satisfactorily responded to corticosteroid. To our knowledge, this is the first reported case of SjS with AIH and antiphospholipid antibody syndrome (APAS). Analysis of serum cytokine levels showed a predominance of Th0-Th1 response, which is not compatible with AIH, in this complicated autoimmune state.(Internal Medicine 39: 73-76, 2000)
- 2000-01-01
著者
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FUJII Hiroshi
Department of Hematology, Kyoto First Red Cross Hospital
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Katayama Yoshio
Department Of Internal Medicine Kobe West City Hospital
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Katayama Yoshio
Department Of Hematology And Oncology Graduate School Of Medicine University Of Tokyo
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Kirizuka Keiji
Department Of Internal Medicine Kobe West City Hospital
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Nishizaki Hiroshi
Department Of Fermentation Technology Faculty Of Engineering Hiroshima University
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Nishizaki Hiroshi
Department Of Internal Medicine Kobe West City Hospital
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KOHRIYAMA Kenji
Department of Internal Medicine, Kobe West City Hospital
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TANJI Yoshiaki
Department of Internal Medicine, Kobe West City Hospital
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Tanji Yoshiaki
Department Of Internal Medicine Kobe West City Hospital
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Kohriyama Kenji
Department Of Internal Medicine Kobe West City Hospital
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Fujii Hiroshi
Department Of Forensic Medicine Faculty Of Medicine Fukuoka University
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Katayama Yoshio
Department Of Gastroenterology Aichi Cancer Center Hospital
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Fujii Hiroshi
Department Of Biochemistry Niigata University School Of Medicine
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Fujii Hiroshi
Department Of Internal Medicine Kobe West City Hospital
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Katayama Yoshio
Department Of Cell Pathology Graduate School Of Medical Sciences Kumamoto University
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