Identification of 3,4-Dihydroxy-2-oxo-butanal (L-threosone) as an Intermediate Compound in Oxidative Degradation of Dehydro-L-ascorbic Acid and 2,3-Diketo-L-gulonic Acid in a Deuterium Oxide Phosphate Buffer(Food & Nutrition Science)
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概要
- 論文の詳細を見る
Dehydro-L-ascorbic acid (DAA), an oxidation product of L-ascorbic acid (vitamin C), is unstable in the neutral and basic pH regions. When DAA was incubat- ed in a phosphate buffer with deuterium oxide (pH 7.4), it was degraded to form the main degradation compound, which was identified as 3,4-dihydroxy-2-oxobutanal (L-threosone). This compound was also formed from diketo-L-gulonic acid (DKG) in a phosphate buffer with deuterium oxide. L-threosone had reducing activity, probably due to its enolization, and is likely to have been involved in the formation of the reducing activity that was observed in aqueous DAA and DKG solutions. As a reactive dicarbonyl compound, L-threosone might also take some role in the cross-linking of tissue proteins that are formed in vivo in the Maillard reaction.
- 社団法人日本農芸化学会の論文
- 2001-08-23
著者
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Nishikawa Yoko
Institute Of Environmental Science For Human Life Ochanomizu University
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Nishikawa Yoko
Institute Of Environmental Science For Human Life
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KURATA Tadao
Institute of Environmental Science for Human Life, Ochanomizu University
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Kurata Tadao
Institute Of Environmental Science For Human Life Ochanomizu University
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TOYOSHIMA Yuka
Institute of Environmental Science for Human Life, Ochanomizu University
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Toyoshima Yuka
Institute Of Environmental Science For Human Life Ochanomizu University
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KURATA Tadao
Institute of Environmental Science for Human Life
関連論文
- Effects of 2,3-Diketo-L-gulonic Acid on the Oxidation of Yolk Lipoprotein
- Physiological Role of L-Ascorbic Acid in Rats Exposed to Cigarette Smoke
- Stabilization of L-Ascorbic Acid by Superoxide Dismutase and Catalase
- Formation Mechanism of Monodehydro-L-ascorbic Acid and Superoxide Anion in the Autoxidation of L-Ascorbic Acid
- Interconversion between Dehydro-L-Ascorbic Acid and L-Ascorbic Acid
- Effects of L-Ascorbic Acid and Superoxide Anion Radical on the Polymerization of Ovalbumin
- Chemical characteristics of dehydro-L-ascorbic acid
- Time-Dependent Changes of Tissue Erythorbic Acid Concentrations in Guinea Pigs
- Autoxidation Reaction Mechanism for L-Ascorbic Acid-related Compounds in Methanol without Metal Ion Catalysis
- Autoxidation Reaction Mechanism for L-Ascorbic Acid in Methanol without Metal Ion Catalysis