Delection of Antifungal Activity in Belamcanda chinensis by a Single-cell Bioassay Method and Isolation of Its Active Compound, Tectorigenin
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概要
- 論文の詳細を見る
The antifungal activity of Belamcanda chinensis evaluated by a single-cell bioassay method. An active fraction was separated by silica gel column chromatography and reverse-phase HPLC. The isolated compound was found to be identical to tectorigenin (5,7-dihydroxy-3-(4-hydroxy phenyl)-6-methoxy-4H-1-benzopyran-4-one) which has formerly appeared in the literature without any remarks on its antimicrobial activity. Antimicrobial activity was investigated against 17 strains of fungi and 6 strains of bacteria. This compound showed marked antifungal activity against dermatophytes of the genera Trichophyton, the minimum inhibitory concentration (MIC) being in the range of 3.12-6.25 mg/ml.
- 社団法人日本農芸化学会の論文
- 2001-04-23
著者
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OH KI-BONG
Natural Products Research Institute, Seoul National University
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MATSUOKA HIDEAKI
Department of Biotechnology, Faculty of Technology, Tokyo University of Agriculture and Technology
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Oh Ki-bong
Natural Products Research Institute Seoul National University
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KANG Heonjoong
MBCL, Oceanographic Program, School of Earth and Environmental Sciences, Seoul National University
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Kang Heonjoong
Mbcl Oceanographic Program School Of Earth And Environmental Sciences Seoul National University
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Matsuoka Hideaki
Department Of Biotechnology And Life Science Faculty Of Technology Tokyo University Of Agriculture A
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Matsuoka Hideaki
Department Of Biotechnology Faculty Of Technology Tokyo University Of Agriculture Technology
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