Production of a Cloned Mouse by Nuclear Transfer from a Fetal Fibroblast Cell of a Mouse Closed Colony Strain
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概要
- 論文の詳細を見る
We have tested a closed colony mouse strain as a source for nuclei donors to determine differences in cloning efficiency. When donor nuclei were isolated from fetal fibroblast cells and injected into recipient oocytes from closed colony mice (ICR), reconstructed oocytes developed to full term and the success rate of cloning was 0.1%. This result indicates that cloning efficiency does not depend on the cell type. The body weight of the cloned mouse was lighter than controls, and the lifetime of the cloned mouse was the average for a mouse. These results contradict commonly-held views on cloning.
- 社団法人 日本実験動物学会の論文
著者
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SAITO MIKAKO
Department of Biotechnology, Faculty of Technology, Tokyo University of Agriculture and Technology
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MATSUOKA HIDEAKI
Department of Biotechnology, Faculty of Technology, Tokyo University of Agriculture and Technology
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Saga A
Tokyo Univ. Agriculture And Technol. Tokyo Jpn
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Sasaki Mami
Plant Science Center Riken
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Saito Mikako
Department Of Biotechnology And Life Science Tokyo University Of Agriculture And Technology
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Matsuoka Hideaki
Department Of Biotechnology And Life Science Faculty Of Technology Tokyo University Of Agriculture A
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Matsuoka Hideaki
Department Of Biotechnology And Life Science Tokyo University Of Agriculture And Technology
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Saga Ayako
Department Of Biotechnology And Life Science Tokyo University Of Agriculture And Technology
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Saito Mikako
Tokyo Univ. Agriculture And Technol. Tokyo Jpn
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