Dietary β-and γ-Cyclodextrins Stimulation of Hepatic Metallothionein Gene Expression in Rats
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概要
- 論文の詳細を見る
This study investigated whether hepatic metallothionein gene expression is affected by dietary cyclodextrins. Young male Wistar rats were fed a basal diet or cyclodextrin-supplemented (50g of cyclodextrin per kg diet) diets for 7d. Copper content in the liver did not show any significant changes among rats fed the basal, β-and γ-cyclodextrin diets. There were no differences in liver or serum zinc among groups. Copper content in serum was markedly decreased in rats fed the γ-cyclodextrin-supplemented diet. Liver metallothionein mRNA levels were significantly elevated in both β-and γ-cyclodextrins-fed rats, but not in α-cyclodextrin-fed rats. Thus, the increase in hepatic metallothionein mRNA levels might be due to this mechanism except for the contents of copper and zinc in the liver.
- 社団法人日本農芸化学会の論文
- 2000-11-23
著者
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AOYAMA Yoritaka
Division of Applied Bioscience, Graduate School of Agriculture, Hokkaido University
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Okada M
Amano Enzyme Inc. Gifu R&d Center Gifu Jpn
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Aoyama Y
Hokkaido Univ. Sapporo Jpn
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KAEWPRASERT Sarunya
Division of Applied Bioscience, Graduate School of Agriculture, Hokkaido University
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OKADA Minoru
Nihon Shokuhin Kako Co. Ltd.
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Aoyama Yoritaka
Division Of Applied Bioscience Graduate School Of Agriculture Hokkaido University
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Kaewprasert Sarunya
Division Of Applied Bioscience Graduate School Of Agriculture Hokkaido University
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