Syntheses of 1-O-[5-(Carboxy)pentanoyl]-2-deoxy-2-(2,2-difluorotetradecanamido)-3-O-[(R)-3-(tetradecanoyloxy)tetradecanoyl]-4-O-phosphono-α-D-glucopyranose and Its Analogues

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概要

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• 1-O-[5-(Carboxy) pentanoyl]-2-deoxy-2-(2,2-difluorotetradecanamido)-3-O-[(R)-3-(tetradecanoyl-oxy)tetradecanoyl]-4-O-phosphono-α-D-glucopyranose (13) and its analogues (16 and 19) were synthesized. Compound 13 showed strong LPS-agonistic activity.

• 社団法人日本農芸化学会の論文
• 1995-03-23

著者

• Arai Masami

  Exploratory Chemistry Research Laboratories Sankyo Co. Ltd.

• Maeda H

  Kyoto Univ. Kyoto

• SHIOZAKI Masao

  Exploratory Chemistry Research Laboratories, Sankyo Co., Ltd.

• KURAKATA Shin-ichi

  Biological Research Laboratories, Sankyo Co., Ltd.

• NISHIJIMA Masahiro

  Department of Biochemistry and Cell Biology, National Institute of Health

• Makino Hiroyuki

  Corporate Research & Development Laboratories Sumitomo Metal Industries Limited

• Ogawa J

  Kyoto Univ. Kyoto Jpn

• Miyazaki Hideki

  Exploratory Chemistry Research Laboratories, Sankyo Co., Ltd.

• Hiraoka Tetsuo

  Exploratory Chemistry Research Laboratories, Sankyo Co., Ltd.

• Tatsuta Tohoru

  Biological Research Laboratories, Sankyo Co., Ltd.

• Ogawa Junko

  Biological Research Laboratories, Sankyo Co., Ltd.

• Akamatsu Yuzuru

  Department of Biochemistry and Cell Biology, National lnstitute of Health

• Arai M

  Exploratory Chemistry Research Laboratories Sankyo Co. Ltd.

• Tatsuta Tohoru

  Biological Research Laboratories Sankyo Co. Ltd.

• Arai M

  Division Of Materials Science And Engineering Graduate School Of Engineering Hokkaido University

• Shiozaki M

  Exploratory Chemistry Research Laboratories Sankyo Co. Ltd.

• Shiozaki Masao

  Chemical Research Laboratories Sankyo Co. Ltd.

• Shiozaki Masao

  Exploratory Chemistry Research Laboratories Sankyo Co. Ltd.

• Makino H

  Corporate Research & Development Laboratories Sumitomo Metal Industries Limited

• Miyazaki H

  Exploratory Chemistry Research Laboratories Sankyo Co. Ltd.

• Ogawa J

  Division Of Applied Life Sciences Graduate School Of Agriculture Kyoto University

• Nishijima Masahiro

  Department Of Biochemistry And Cell Biology National Institute Of Health

• Ogawa J

  Inst. Energy Economics Japan

• Hiraoka Tetsuo

  Exploratory Chemistry Research Laboratories Sankyo Co. Ltd.

• Kurakata S

  Biological Research Laboratories Sankyo Co. Ltd.

• Kurakata Shin-ichi

  Biological Research Laboratories Sankyo Co. Ltd.

• Akamatsu Yuzuru

  Bioactive Molecules Research Group Microbial Chemistry Research Center

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