CREATINE KINASE BB ISOZYME IN THE BLOOD DURING OPEN HEART SURGERY : Comparison with Creatine Kinase MB and MM Isozymes
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概要
- 論文の詳細を見る
By using a recently developed highly sensitive enzyme immunoassay method, concentrations of the 3 forms of cytoplasmic creatine kinases (CK-BB, CK-MB and CK-MM) were determined in blood samples serially taken from 18 patients who recieved mitral valve replacement. Blood CK-BB levels, 0.64 ± 0.32 ng/ml at the beginning of anesthesia, rose sharply after reperfusion reaching the peak level (23.3 ± 7.56 ng/ml) 2 hours after reperfusion, and then fell rapidly. The response of CK-BB in blood was rapider and more sensitive than that of CK-MB or CK-MM. The CK-BB concentrations were significantly higher in coronary sinus samples than in arterial samples. These results suggest that the major portion of elevate blood CK-BB level in the early phase after reperfusion are derived from the heart muscle.
- 社団法人日本循環器学会の論文
- 1989-02-20
著者
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ABE TOSHIO
Department of Urology, Aichi Medical University School of Medicine
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KATO Kanefusa
Department of Biochemistry, Institute for Developmental Research, Aichi Prefecture Colony
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Abe Toshio
Department Of Thoracic Surgery Nagoya University School Of Medicine
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Takeuchi Eiji
Department Of Thoracic Surgery Nagoya University School Of Medicine
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USUI AKIHIKO
Department of Thoracic Surgery, Nagoya University School of Medicine
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TANAKA MINORU
Department of Thoracic Surgery, Nagoya University School of Medicine
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ABE Toshio
Nagoya University School of Medicine.
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MURASE MITUYA
Department of Thoracic Surgery, Nagoya University School of Medicine
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Murase Mitsuya
Department Of Thoracic Surgery Oogaki Municipal Hospital
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Murase Mitsuya
Department Of Thoracic Surgery Ogaki Municipal Hospital
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Takeuchi Eiji
Department Of Cardiovascular Surgery Nagoya National Hospital
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Kato Kanefusa
Department Of Biochemistry Institute For Developmental Research Aichi Prefectural Colony
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Usui Akihiko
Department Of Cardiothoracic Surgery Nagoya University Graduate School Of Medicine
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Kato Kanefusa
Department Of Biochemistry Institute For Developmental Research
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Murase Mituya
Department Of Thoracic Surgery School Of Medicine Nagoya University
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Abe Toshio
Department Of Internal Medicine Kanazawa Municipal Hospital
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Abe Toshio
Ist Div. Dept. Of Surg. (prof. H. Hashimoto) School Of Med. Nagoya University Nagoya
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Tanaka Minoru
Department Of Thoracic Surgery Nagoya University School Of Medicine
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Abe Toshio
Department Of Cardiovascular Surgery Japanese Red Cross Nagoya First Hospital
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Tanaka Minoru
Department Of Anatomy Kyoto Prefectural University Of Medicine
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Takeuchi Eiji
The First Department Of Surgery Nagoya University School Of Medicine
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Abe Toshio
1st Dept. Of Surg. Univ. Of Nagoya
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Usui Akihiko
Department Of Cardiac Surgery Nagoya University Graduate School Of Medicine
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