CHANGES IN BLOOD PRESSURE AND PLASMA NOREPINEPHRINE DURING SLEEP IN ESSENTIAL HYPERTENSION
スポンサーリンク
概要
- 論文の詳細を見る
A fall in blood pressure (BP) and the presence of a period of unstable BP during sleep has been reported in humans. However the mechanisms responsible for these phenomena are unclear. In order to examine the role of the sympathetic nervous system in these phenomena, plasma norepinephrine (PNE) was measured in patients with essential hypertension. Blood pressure was monitored under unrestricted conditions by a canula inserted into the brachial artery. During sleep, systolic (SBP) and diastolic blood pressure (DBP) fell by 18.8/13.7 mmHg, respectively. The magnitude of the fall in SBP correlated significantly (p<0.05) with the level of PNE in the daytime and with the magnitude of the fall in PNE during sleep. The period of unstable BP and pulse rate was observed during sleep. During this unstable period, BP changed periodically with 20 to 120-second cycles associated with parallel changes in pulse rate. PNE during this period was higher (p<0.05) than that during the period of stable BP during sleep. These data suggest that the sympathetic nervous system may play an important role in the fall in BP and unstability of BP during sleep.
- 社団法人日本循環器学会の論文
- 1987-11-20
著者
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Umemura Satoshi
the Second Department of Internal Medicine, Yokohama City University School of Medicine
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Kaneko Yoshihiro
Second Department Of Internal Medicine Yokohama City University Hospital
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Kaneko Yoshihiro
Department Of Internal Medicine Jikei University School Of Medicine
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Kobayashi Yoshio
Cardiovascular Division National Cardiovascular Center
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Tochikubo Osamu
The Second Department Of Internal Medicine Yokohama City University School Of Medicine
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KANEKO YOSHIHIRO
The Second Department of Internal Medicine,School of Medicine,Yokohama City University
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Kobayashi Kiminari
The Second Department of Internal Medicine, Yokohama City University, School of Medicine
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Umemura Satoshi
The Second Department Of Internal Medicine Yokohama City University
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Kaneko Yoshihiro
The Second Department Of Internal Medicine Yokohama City University
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Shindo Tadashi
The Second Department of Internal Medicine Yokohama City University School of Medicine
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Tochikubo Osamu
The Second Department Of Internal Medicine Yokohama City University
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Kaneko Yoshihiro
The Second Department Of Internal Medicine Yokohama City University School Of Medicine
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Kobayashi Kiminari
The Second Department Of Internal Medicine Yokohama City University School Of Medicine
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Kobayashi Kiminari
2nd Department Of Internal Medicine Yokohama City University School Of Medicine
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Kobayashi Kiminari
2nd Dept. Of Intern. Med. Yokohama City Univ. School Of Med.
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Yoshihiro Kanako
Second Department Of Internal Medicine Yokohama City University Hospital
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NODA KAZUMASA
The Second Department of Internal Medicine Yokohama City University School of Medicine
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Kaneko Y
Second Department Of Internal Medicine Yokohama City University School Of Medicine
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Kimura Yoshio
2nd Department Of Internal Medicine Faculty Of Medicine University Of Tokyo
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Yoshinaga Keiichiro
Department Of Photobiology Division Of Molecular Cellular Imaging Hokkaido University Graduate Schoo
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