Association of carotid atherosclerosis with genetic polymorphisms of the klotho gene in patients with hypertension
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概要
- 論文の詳細を見る
- 2010-10-01
著者
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KOKUBO Yoshihiro
Division of Preventive Cardiology, National Cardiovascular Center
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OKAMURA Tomonori
Division of Preventive Cardiology, National Cardiovascular Center
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OHISHI Mitsuru
Department of Geriatric Medicine, Osaka University Graduate School of Medicine
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RAKUGI Hiromi
Department of Geriatric Medicine, Osaka University Graduate School of Medicine
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北 徹
Department Of Geriatric Medicine Osaka University Graduate School Of Medicine
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北 徹
京都大学大学院医学研究科循環器内科学
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北 徹
京都大学老年科
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荻原 俊男
Division Of Preventive Cardiology National Cardiovascular Center
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HORIO Takeshi
National Cardiovascular Center
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KATSUYA Tomohiro
Osaka University
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Kikuchi Kenjiro
Second Department Of Internal Medicine Sapporo Medical College
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Kaikita Koichi
Department Of Cardiovascular Medicine Graduate School Of Medical Sciences Kumamoto University
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Kita Toru
京都大学 医学研究科循環器内科学
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Kita Toru
Department Of Cardiovascular Medicine Kobe City Medical Center General Hospital
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SHIMAOKA Izumi
Department of Geriatric Medicine, Osaka University Graduate School of Medicine
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KAMIDE Kei
Department of Geriatric Medicine, Osaka University Graduate School of Medicine
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KATSUYA Tomohiro
Department of Clinical Gene Therapy, Osaka University Graduate School of Medicine, Suita
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CONGRAINS Ada
Department of Geriatric Medicine, Osaka University Graduate School of Medicine
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喜多 義邦
Division Of Preventive Cardiology National Cardiovascular Center
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Kamide Kei
国立循環器病センター 高血圧腎臓内科
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Kotani Yasushi
国立循環器病センター 予防検診
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Kikuchi Kenjiro
The 2nd Department Of Internal Medicine Sapporo Medical College
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Harada Takashi
Division Of Nephrology Clinical Research Center National Kyushu Medical Center
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KIMURA Kenjiro
St. Marianna University School of Medicine
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Kosakai Yoshio
Department Of Cardiovascular Surgery National Cardiovascular Center
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Ohama Tohru
大阪大学 医学系研究科循環器内科学
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Kita Toru
Department Of Geriatric Medicine Graduate School Of Medicine Kyoto University
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Katsuya Tomohiro
東北大学 臨床薬学
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Komamura Kazuo
Department Of Cardiovascular Dynamics Research Institute National Cardiovascular Center
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Kawano Yuhei
国立循環器病センター 高血圧腎臓内科
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Kawano Yuhei
Division Of Hypertension And Nephrology National Cardiovascular Center
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Rakugi Hiromi
東北大学 臨床薬学
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Kamide Kei
国立循環器病センター 予防検診部
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Kohara Katsuhiko
東北大学 臨床薬学
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Tochikubo Osamu
横浜市立大学 第2内科
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Horio Takeshi
国立循環器病センター 高血圧腎臓内科
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Kaneko Yoshihiro
Second Department Of Internal Medicine Yokohama City University Hospital
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Kario Kazuomi
自治医科大学 地域医療学
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Miyata Toshiyuki
Research Institute National Cardiovascular Center
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Kamide Kei
Department Of Geriatric Medicine Ehime University Graduate School Of Medicine
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Kitamura K
Division Of Circulatory And Body Fluid Regulation Faculty Of Medicine Department Of Internal Medicin
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Kurose K
Department Of Vascular Physiology Research Institute National Cardiovascular Center
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Kokubo Yoshihiro
国立循環器病センター研究所 疫学部
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Kokubo Yoshihiro
愛媛大学 医学系研究科医療環境情報解析学講座公衆衛生健康医学
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Kataoka Keiichiro
Kumamoto Ami Study Group
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Takahashi Hakuo
Department Of Cardiovascular Medicine Shinshu University Graduate School Of Medicine
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Ohama Tohru
Department Of Cardiovascular Medicine Osaka University Graduate School Of Medicine
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Tochikubo Osamu
Division Of Cardiology Yokohama City University Medical Center
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Kaneda Yasufumi
Division Of Gene Therapy Science Osaka University
-
Kawamura Tetsuya
東京慈恵会医科大学 腎臓・高血圧内科
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Kawamura T
The Division Of Nephrology And Hypertension
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Ohkubo Takayoshi
東北大学 臨床薬学
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Ohkubo Takayoshi
The Department Of Public Health Tohoku University Graduate School Of Pharmaceutical Science And Medi
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荻原 俊男
大阪大 大学院医学系研究科 生体制御医学専攻 加齢医学
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Okura Takafumi
愛媛大学 医学系研究科病態情報内科学
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Kawamura Keishiro
大阪医科大学 内科学iii
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Kawamura Keishiro
The Third Division Internal Medicine Osaka College
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Kohagura Kentaro
琉球大学 第三内科
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Ohtsuka Tomoaki
愛媛大学 医学系研究科臨床看護学
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Kayaba Kazunori
自治医科大学 地域医療学
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荻原 俊男
大阪大学 加齢医学
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Kohara Katsuhiko
愛媛大学 医学部老年医学
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Kaneko Yoshihiro
Department Of Internal Medicine Jikei University School Of Medicine
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Katsuya Tomohiro
Department Of Clinical Gene Therapy Osaka University Graduated School Of Medicine
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HORIO Takeshi
Division of Hypertension and Nephrology, National Cardiovascular Center
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KIMURA Tokihisa
Furukawa City Hospital
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Kawano Yuhei
Division Of Hypertension And Nephrology Department Of Internal Medicine National Cardiovascular Cent
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Kobayashi Yoshio
Cardiovascular Division National Cardiovascular Center
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Kizu Takashi
大阪大学 医学系研究科内分泌・代謝内科
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Morisaki Takayuki
国立循環器病センター 心臓血管内科
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Ohishi Mitsuru
Department Of Geriatric Medicine Osaka University Graduate School Of Medicine
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Katanosaka Yuki
国立循環器病センター
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Honda Takeshi
Department Of Hypertension And Cardiorenal Medicine Dokkyo University School Of Medicine
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喜多 義邦
島根大学 医学部環境保健医学講座公衆衛生学
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Tanaga Kosei
千葉県循環器病センター 循環器科
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Tochikubo Osamu
The Second Department Of Internal Medicine Yokohama City University School Of Medicine
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Kimura Kenjiro
Division Of Cardiology Yokohama City University Medical Center
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Rakugi Hiromi
Department Of Geriatric Medicine
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Obara Taku
東北大学 臨床薬学
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Obara Taku
Department Of Clinical Pharmacology And Therapeutics Tohoku University Graduate School Of Pharmaceut
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Hayashi Hiroki
Department Of Geriatric Medicine And Nephrology Osaka University Graduate School Of Medicine
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Kosakai Yoshio
Department Of Cardiovascldar Surgery National Cardiovascudar Center
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Okuda Tomohiko
国立循環器病センター研究所 疫学部
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Okuda Tomohiko
Research Institute National Cardiovascular Center
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Kokubo Yoshihiro
Department Of Preventive Cardiology National Cardiovascular Center
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Kimura Kazuo
Division Of Cardiology Yokohama City University Medical Center
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荻原 俊男
大阪大学 医学部 加齢医学 講座
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Hanada Hironori
Research Institute National Cardiovascular Center
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Miyata Toshiyuki
Department Of Clinical Gene Therapy Osaka University Graduate School Of Medicine
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Tanaka H
Department Of Urology Kawasaki Medical School
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Kitamura K
Faculty Of Medicine Department Of Internal Medicine Division Of Circulatory And Body Fluid Regulatio
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Tanno Kaoru
Third Department Of Internal Medicine Showa University
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Morisaki T
Department Of Bioscience National Cardiovascular Center Research Institute
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Takahashi Hakuo
Clinical Laboratory Medicine Kansai Medical University
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Horio Takeshi
Division Of Hypertension And Nephrology Department Of Medicine National Cardiovascular Center
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Kangawa K
Research Institute National Cardiovascular Center
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Okuda Tomohiro
Research Institute National Cardiovascular Center
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Kohara Katsuhiko
Department Of Geriatric Medicine Ehime Unviersity School Of Medicine
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Kokubo Yoshihiro
Cardiovascular Division National Cardiovascular Center
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Tamura Kouichi
Second Department Of Internal Medecine Yokohama City University School Of Medicine
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Kawamura Keishiro
Department Of Internal Medicine (iii) Osaka Medical College
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Miyata Toshiyuki
Division of Hypertension and Nephrology, Department of Medicine, National Cardiovascular Center
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HARADA Takashi
Ministry of Health and Welfare of Japan and Japanese Society of Nephrology
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Ojima Toshiyuki
Hamamatsu Univ. School Of Medicine
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Okubo Takayoshi
Department Of Planning For Drug Development And Clinical Evaluation Tohoku University
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Kawagoe Yasuhiro
HIJC Investigators
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Kikuchi Kan
Department Of Blood Purification Kidney Center Tokyo Women's Medical University
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Kokubo Yoshihiro
Division Of Cardiovascular Preventive Medicine National Cardiovascular Center
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Rakugi Hiromi
Division Of Cardiology Sakurabashi Watanabe Hospital
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Kihara Koichi
Department Of Geriatric Medicine Osaka University Medical School
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Kawamura Tetsuya
The Division Of Nephrology And Hypertension
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Kammatsuse Katsuo
Nihon University
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Kubota Tomoko
Department of Clinical Pharmacology and Pharmacogenomics
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Kuwasako Takahiro
Suita Municipal Hospital
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Takano Makoto
Division Of Molecular Physiology And Biophysics Department Of Physiology Jichi Medical University
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Takano M
Division Of Biophysics Department Of Physiology Jichii Medical School
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Kitamura Kazuo
First Department Of Internal Medicine University Of Miyazaki
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Kakeji Yosihiro
九州大学 医学研究院消化器・総合外科
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Kobayashi Toru
Center for Adult Diseases
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Kikkawa Toshiro
Sumitomo Hospital
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OGURO Ryosuke
Department of Geriatric Medicine, Osaka University Graduate School of Medicine
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Okura Takafumi
The Second Department Of Internal Medicine Ehime University School Of Medicine
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Yoshita Katsushi
Project For The National Health And Nutrition Survey National Institute Of Health And Nutrition
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Ogihara Toshio
Department Of Medicine And Gerictrics Osaka University Medical School
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Tochikubo Osamu
The Second Department Of Internal Medicine Yokohama City University
-
Okura Takafumi
Department Of Planning For Drug Development And Clinical Evaluation Tohoku University
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Kadoshima Yoko
Department Of Public Health Kanazawa Medical University
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Kawamura Tetsuya
Second Department Of Internal Medicine Jikei University School Of Medicine
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Kawamoto Takahiro
Department Of Geriatric Medicine Graduate School Of Medicine Kyoto University
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Mannami Toshifumi
Department Of Preventive Cardiology National Cardiovascular Center
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KANAGAWA KENJI
National Cardiovascular Center Research Institute
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Kato Ken
Division Of Gastrointestinal Oncology National Cancer Center Hospital
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Kita Toru
Department Of Clinical Bio-regulatory Science Division Of Molecular Medicine For Adult And Geriatric
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Kikkawa Toshiro
Department Of Cardiology National Hospital Organization Kure Medical Center
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Kita Toru
Department Of Cardiology Kyoto University
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Kikuchi Kenjiro
The Second Department Of Internal Medicine Sappolo Medical College
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Kanatsu Kazuro
Department Of Internal Medicine Hyogo Hospital
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Kosakai Yoshio
National Cardiovascular Center
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Okamura Tomonori
Department Of Health Science Shiga University Of Medical Science
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Kaneda Yoshio
The 1st Dept. Of Pathology Tokyo Women's Medical College
-
Oguro Ryosuke
Department Of Geriatric Medicine Osaka University Graduate School Of Medicine
-
Kojima Tozo
Department Of Nephrology And Endocrinology University Of Tokyo Faculty Of Medicine
-
Kamide Kei
St. Marianna University School Of Medicine
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Ohtsuka Tomoaki
Department Of Integrated Medicine And Informatics Ehime University Graduate School Of Medicine
-
Okamura Tomonori
Division Of Preventive Cardiology National Cardiovascular Center
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Miyata Toshiyuki
Department Of Preventive Cardiology National Cardiovascular Center:hygiene And Public Health Social
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Kitamura Kouichi
Internal Medicine Nephrology And Hypertension St. Marianna University School Of Medicine
-
Ohtsuki Taisuke
Nervous And Muscular Disorders National Center For Neurology And Psychiatry
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Katsuya Tomohiro
The Department Of Geriatric Medicine Osaka University Medical School
-
Kataoka Keiichiro
Department Of Physiological Chemistry And Metabolism Graduate School Of Medicine The University Of T
-
Kadota K
Department Of Internal Medicine Hyogo Hospital
-
Ogihara T
Osaka Univ. Medical School Osaka Jpn
-
Horiguchi Takashi
Department Of Neurosurgery Keio University School Of Medicine
-
Kanagawa Kenji
Research Institute National Cardiovascular Center
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Kudoh Kei
The Second Department Of Internal Medicine Tohoku University School Of Medicine
-
Kita Toru
Division Of Cardiology Kobe City Medical Center General Hospital
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Oguro Ryousuke
Department Of Geriatric Medicine Osaka University Graduate School Of Medicine
-
Kokubo Yoshihiro
国立循環器病センター 予防検診部
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Yoshihiro Kanako
Second Department Of Internal Medicine Yokohama City University Hospital
-
Komamura Kazuo
Department Of Cardiovascular Medicine National Cardiovascular Center
-
Ogihara Toshio
Department Of Medicine And Geriatrics Osaka University Medical School
-
Kamide Kei
Department Of Cardiovascular Medicine Nephrology And Neurology Faculty Of Medicine And Dialysis Unit
-
Kanatsu Kazuro
The 3rd Division Department Of International Medicine Faculty Of Medicine
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Konta Tsuneo
First Department Of Medicine Yamagata University
-
Congrains Ada
Department Of Geriatric Medicine Osaka University Graduate School Of Medicine
-
Katuya Tomohiro
Department Of Geriatric Medicine Osaka University Graduate School Of Medicine
-
Shimaoka Izumi
Department Of Geriatric Medicine Osaka University Graduate School Of Medicine
-
Hanasaki Hiroko
Department Of Geriatric Medicine And Nephrology Osaka University Graduate School Of Medicine
-
Kitahara Koichi
Department Of Cardiology Sakakibara Heart Institute
-
Kobayashi Toru
Second Department Of Internal Medicine Osaka University Medical School Center Of Adult Disease
-
HANADA Hironori
Divisions of Research Institute, National Cardiovascular Center
-
Onishi Toshio
Department Of Geriatric Medicine Osaka University Medical School
-
Kakizawa Yoshiko
Department Of Cardiology Tokyo Women's Medical University
-
Kouno Kouichi
Department Of Medicine Division Of Hypertension And Cardiorenal Disease Dokkyo University School Of
-
Hanada Hironori
Divisions Of Research Institute National Cardiovascular Center
-
Horio Takeshi
Divisions Of Hypertension And Nephrology National Cardiovascular Center
-
Kogure T
Department Of Internal Medicine And Cardiorenal Medicine Yokohama City University Graduate School Of
-
Kodama Kazuhisa
Cardiac Intensive Care Unit Of Osaka Police Hospital
-
Kuwahara Koichiro
Department Of Medicine And Clinical Sciences Graduate School Of Medicine Kyoto University
-
Kita Toru
National Hospital Organization And Department Of Cardiovascular Medicine Graduate School Of Medicine
-
Kamide Kei
Division Of Cardiovascular Medicine Department Of Medicine School Of Medicine Jichi Medical Universi
-
Tanaka Hiroyoshi
Department Of Urology Kawasaki Medical School
-
Kawamura Tetsuya
Department Of Nephrology And Hypertension School Of Medicine Jikei University
-
Katsuya Tomohiro
Department Of Clinical Gene Therapy Osaka University Graduate School Of Medicine
-
Morisaki Takayuki
Department Of Medicine University Of Pennsylvania
-
Ogihara Toshio
The Department Of Medicine And Clinical Science Graduate School Of Medical Sciences Kyushu Universit
-
Rakugi Hiromi
Department Of Geriatric Medicine And Nephrology Osaka University Graduate School Of Medicine
-
Honda Takeshi
The Department Of Hypertension And Cardiorenal Medicine Dokkyo University School Of Medicine
-
Kitamuara Kazuo
First Department Of Internal Medicine University Of Miyazaki
-
Kamide Kei
Department Of Cardiovascular Medicine Graduate School Of Medicine University Of Tokyo
-
Kangawa Kenji
National Cerebral And Cardiovascular Center Research Institute
-
Miyake Takashi
Division Of Clinical Gene Therapy Osaka University Graduate School Of Medicine
-
Tatsumi Koichiro
Department Of Respirology (b2) Graduate School Of Medicine Chiba University
-
Kimura Kenjiro
Department Of Cardiovascular Medicine Nephrology And Neurology Faculty Of Medicine University Of The
-
Kobayashi Tatsuya
Department Of Nephrology Saitama Medical College
-
Kitamura Kouichi
Department Of Cardiovascular Medicine Nephrology And Neurology Faculty Of Medicine And Dialysis Unit
-
Tamura Kouichi
Division Of Kidney And Hypertension Department Of Internal Medicine The Jikei University School Of M
-
Hagino Takeshi
Divisions Of Hypertension And Nephrology National Cardiovascular Center
-
Horie Takashi
Department Of Cardiovascular Medicine Shinshu University Graduate School Of Medicine
-
Kangawa Keriji
Department Of Biochemistry National Cardiovascular Center Research Institute
-
Kikuchi Kenjiro
Department Of Cardiovascular Medicine Nephrology And Neurology Faculty Of Medicine University Of The
-
Kurose Kouichi
Division Of Internal Medicine And Thoracic Oncology National Cancer Center Hospital
-
Konta Tsuneo
Department Of Neurology Hematology Metabolism Endocrinology And Diabetes Yamagata University School
-
Kamide Kei
Cardiovascular Division Osaka Police Hospital
-
Miura Toshie
Department Of Ophthalmology Hokkaido University Graduate School Of Medicine
-
Kubota Kaoru
Division Of Internal Medicine And Thoracic Oncology National Cancer Center Hospital
-
Horio Takeshi
Division Of Hypertension And Nephrology
-
Hirose Takuo
Department Of Preventive And Public Health Dentistry Fukuoka Dental Colledge
-
Ohishi Mitsuru
Department Of Geriatric Medicine And Nephrology Osaka University Graduate School Of Medicine
-
Oguro Ryosuke
Department Of Geriatric Medicine And Nephrology Osaka University Graduate School Of Medicine
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- OE-318 Geneic Variants of Adrenoceptors Play Key Roles in the Pathogenesis of Hypertension and Obesity(Hypertension, clinical-2 (H) OE54,Oral Presentation (English),The 70th Anniversary Annual Scientific Meeting of the Japanese Circulation Society)
- Association between senescence-related uncoupling protein 2 gene polymorphisms and abdominal obesity in Japanese subjects : The Tanno and Sobetsu study
- Gene Polymorphism of Myospryn (Cardiomyopathy-Associated 5) Is Associated with Left Ventricular Wall Thickness in Patients with Hypertension
- Association between PPAR γ polymorphism and hypertension in Japanese
- Effects of Antihypertensive Drugs and Gene Variants in the Renin-Angiotensin System
- Lack of Correlation between Mbo I Restriction Fragment Length Polymorphism of Renin Gene and Essential Hypertension in Japanese
- Association of Polymorphism in the Promoter Region of the Apolipoprotein E Gene with Diastolic Blood Pressure in Normotensive Japanese
- Polymorphism of myospryn is associated with left ventricular diastolic dysfunction
- -P118-ENDOTHELIN ENHANCES ADRENERGIC VASOCONSTRICTION IN RAT : Hypertension : FREE COMMUNICATIONS(III) : PROCEEDINGS OF THE 53th ANNUAL SCIENTIFIC MEETING OF THE JAPANESE CIRCULATION SOCIETY
- Lower Plasma Adiponectin Concentration Increases Risk for Hypertension
- C-Reactive Protein, Left Ventricular Mass Index, and Risk of Cardiovascular Disease in Essential Hypertension
- PE-454 Pulmonary Venous Ratio of Systolic to Diastolic Wave as a Predictor of Cardiovascular Disease in Essential Hypertension(Hypertension, clinical-05, The 71st Annual Scientific Meeting of the Japanese Circulation Society)
- PE-444 C-Reactive Protein in Essential Hypertension : Association with Left Ventricular Mass Index and Risk of Cardiovascular Disease(Hypertension, clinical-04, The 71st Annual Scientific Meeting of the Japanese Circulation Society)
- Association of Sixty-One Non-Synonymous Polymorphisms in Forty-One Hypertension Candidate Genes with Blood Pressure Variation and Hypertension
- Effect of kihito extract granules on cognitive function in patients with Alzheimer's-type dementia
- A Novel Mouse Model for Type 2 Diabetes and Non-alcoholic Fatty Liver Disease : Spontaneous Amelioration of Diabetes by Augmented Beta Cell Mass
- 2 Estrogen Decreases the Activation of RANK-RANKL System in Vascular Calcification(Young Investigator's Award for International Students Finalists Lecture (YIA International),The 73rd Annual Scientific Meeting of The Japanese Circulation Society)
- OJ-195 Pivotal Roles of Deubiquitinating Enzymes UCHL1, HAUSP, and CYLD in Vasculature as an Anti-proliferative and Anti-inflammatory Effect(Atherosclerosis, basic-3, The 71st Annual Scientific Meeting of the Japanese Circulation Society)
- A Novel Missense Mutation, F826Y, in the Mineralocorticoid Receptor Gene in Japanese Hypertensives : Its Implications for Clinical Phenotypes
- PJ-098 Ubiquitin C-terminal Hydroxylase L1 (UCHL1), the Causative Genes of Inherited Parkinson's Disease, Has an Anti-inflammatory Action in Endothelial Cells(Molecular biology, vascular-3 (H) PJ17,Poster Session (Japanese),The 70th Anniversary Annual Sci
- Klotho gene delivery suppresses oxidative stress in vivo
- -P121-ENDOTHELIN INHIBITS RENIN RELEASE FROM ISOLATED RAT GLOMERULI : Hypertension : FREE COMMUNICATIONS(III) : PROCEEDINGS OF THE 53th ANNUAL SCIENTIFIC MEETING OF THE JAPANESE CIRCULATION SOCIETY
- PJ-243 A Novel Mutation in the Autosomal Recessive Hypercholesterolemia Gene Leads to Hypercholesterolemia(Lipid disorders-3 (H) PJ41,Poster Session (Japanese),The 70th Anniversary Annual Scientific Meeting of the Japanese Circulation Society)
- PJ-125 A Polymorphism in the Promoter of Angiotensinogen Gene is Associated with Adipose Tissue Distribution in Japanese : the Sobetsu Study(Hypertension, Clinical 3 (H) : PJ21)(Poster Session (Japanese))
- Tissue Inhibitor of Metalloproteinase-3 Deficiency Inhibits Blood Pressure Elevation and Myocardial Microvascular Remodeling Induced by Chronic Administration of N^ω-Nitro-L-Arginine Methyl Ester in Mice
- Tissue Inhibitor of Metalloproteinase-3 Plays Important Roles in the Kidney Following Unilateral Ureteral Obstruction
- No increase in human HGF concentration in the patients transfected with human HGF plasmid : preliminary clinical results from TREAT-HGF
- Preliminary clinical results from TREAT-HGF (Japan Trial to Treat Peripheral Arterial Disease by Therapeutic Angiogenesis Using HGF Gene Transfer)
- Intracellular Ca^-elevation Plays a Crucial Role in the PKC-independent Antagonizing Effect of Angiotensinll against Insulin-induced Production of PI(3, 4, 5)P3 in Cardiomyocytes (Molecular Biology, Myocardium 2 (M), The 69th Annual Scientific Meeting
- A Genome-Wide Association Study of Hypertension-Related Phenotypes in a Japanese Population
- The counterregulating role of ACE2 and ACE2-mediated angiotensin 1-7 signaling against angiotensin II stimulation in vascular cells
- Strong suppression of the renin-angiotensin system has a renal-protective effect in hypertensive patients : High-dose ARB with ACE inhibitor (Hawaii) study
- Association of carotid atherosclerosis with genetic polymorphisms of the klotho gene in patients with hypertension