OJ-195 Pivotal Roles of Deubiquitinating Enzymes UCHL1, HAUSP, and CYLD in Vasculature as an Anti-proliferative and Anti-inflammatory Effect(Atherosclerosis, basic-3, The 71st Annual Scientific Meeting of the Japanese Circulation Society)

スポンサーリンク

概要

• 論文の詳細を見る
• 社団法人日本循環器学会の論文
• 2007-03-01

著者

• RAKUGI Hiromi

  Department of Geriatric Medicine, Osaka University Graduate School of Medicine

• KATSUYA Tomohiro

  Department of Clinical Gene Therapy, Osaka University Graduate School of Medicine, Suita

• OGIHARA Toshio

  Department of Geriatric Medicine, Osaka University Graduate School of Medicine

• NAKAGAMI Hironori

  Division of Gene Therapy Science, Osaka University Graduate School of Medicine

• Nakagami Hironori

  Division Of Gene Therapy Science Osaka University Graduate School Of Medicine

• Takami Yoichi

  Department Of Geriatric Medicine And Nephrology Osaka University Graduate School Of Medicine

• KANEDA Yasufumi

  Division of Gene Therapy Science, Graduate School of Medicine, Osaka University

• Tabara Yasuharu

  国立循環器病センター研究所 疫学部

• Niki Hisae

  国立がんセンター中央病院 消化器内科

• Katsuya Tomohiro

  Department Of Clinical Gene Therapy Osaka University Graduated School Of Medicine

• Morishita Ryuichi

  Division Of Gene Therapy Science Osaka University Graduate School Of Medicine

• Nakahama Hajime

  Division Of Hypertension And Nephrology National Cardiovascular Center

• Katanosaka Yuki

  国立循環器病センター

• Rakugi Hiromi

  Department Of Geriatric Medicine

• Nakagami Hironori

  Division Of Clinical Gene Therapy Osaka University Graduate School Of Medicine

• Nonogi Hiroshi

  Saitama Medical University

• Ogihara Toshio

  Department Of Geriatic Medicine

• Kaneda Yasufumi

  Division Of Clinical Gene Therapy Osaka University Graduate School Of Medicine

• Tomino Yasuhiko

  Department Of Medicine Juntendo University School Of Medicine

• TAKADA YASUHARU

  Saijo Central Hospital

• Morishita Ryuichi

  Division Of Clinical Gene Therapy

• Taniyama Yoshiaki

  Department Of Clinical Gene Therapy

• Takemura Yukihiro

  Department Of Geriatric Medicine And Nephrology Osaka University Graduate School Of Medicine

• Nonogi Hiroshi

  Department Of Cardiology Medical School Osaka University

• Nonogi Hiroshi

  Division Of Cardiac Care Unit Department Of Cardiovascular Medicine National Cerebral And Cardiovasc

• Katsuya Tomohiro

  Department Of Clinical Gene Therapy Osaka University Graduate School Of Medicine

• Takami Yoichi

  Department Of Clinical Gene Therapy Osaka University Graduate School Of Medicine

• Morishita Ryuichi

  Department Cf Clinical Gene Therapy Graduate School Of Medicine Osaka University

• Takami Yoichi

  Department Of Cardiology And Hematology Fukushima Medical University

• Morishita Ryuichi

  Division Of Clinical Gene Therapy Graduate School Of Medicine Osaka University

• Hayashi Norihiro

  Department Of Clinical Pharmacology And Pharmacogenomics Graduate School Of Pharmaceutical Sciences Osaka University

関連論文

• Loss of ACE2 accelerates time-dependent glomerular and tubulointerstitial damage in streptozotocin-induced diabetic mice
• Association of gene polymorphism of the fat-mass and obesity-associated gene with insulin resistance in Japanese
• Accumulation of common polymorphisms is associated with development of hypertension : a 12-year follow-up from the Ohasama study
• Prevention of osteoporosis by angiotensin-converting enzyme inhibitor in spontaneous hypertensive rats
• A Promoter Polymorphism of Lamin A/C Gene is an Independent Genetic Predisposition to Arterial Stiffness in a Japanese General Population (The Tanno and Sobetsu Study)
• Genetic basis of hypertension for the development of tailored medicine
• Association of SLC6A9 Gene Variants with Human Essential Hypertension
• Fas promoter region gene polymorphism is associated with an increased risk for myocardial infarction
• Relationship between the achieved blood pressure and the incidence of cardiovascular events in Japanese hypertensive patients with complications : a sub-analysis of the CASE-J trial
• OJ-108 Inhibition of Apop Gene Expression Prevents Death of Cells in Culture Following Hypoxia/Reoxygenation(Cell death, apoptosis/necrosis(M),Oral Presentation(Japanese),The 72nd Annual Scientific Meeting of the Japanese Circulation Society)
• Contribution of Adiponectin Gene Mutation to Coronary Artery Disease
• OE-071 A Genom-Wide Association Study of SNPs in the risk of Atherosclerosis Obliterans(Heart failure, clinical(01)(M),Oral Presentation(English),The 72nd Annual Scientific Meeting of the Japanese Circulation Society)
• DPJ-013 Hepatocyte Growth Factor Attenuates TGF-β1 Angiotensin II Crosstalk by Down Regulation of Angiotensin II Type 1 Receptor through PTEN/Akt Pathway(DPJ03,Kidney/Renal Circulation/CKD (H),Digital Poster Session (Japanese),The 73rd Annual Scientific M
• C allele of angiotensin II type 1 receptor gene A1166C polymorphism affects plasma adiponectin concentrations in healthy young Japanese women
• Negative effects of anemia on quality of life and its improvement by complete correction of anemia by administration of recombinant human erythropoietin in posttransplant patients
• PJ-642 A Polymorphism in Promoter Region of CYP4A11 Gene is Associated with a New Onset of Hypertension : the Tanno-Sobetsu Study(Hypertension, basic-3, The 71st Annual Scientific Meeting of the Japanese Circulation Society)
• Effects of Angiotensin II Type 1 Receptor Gene Polymorphisms on Insulin Resistance in a Japanese General Population : The Tanno-Sobetsu Study
• 4 On-going Japanese Clinical Trials for Hypertension II : Seeking for More Effective Pharmacological Treatment(ESC-JCS Joint Symposium (ESC-JCS Joint Symposium) (H) Evidence-Based Medical Treatment of Hypertension,Special Program,The 72nd Annual Scientifi
• Comparison of Arterial Functional Evaluations as a Predictor of Cardiovascular Events in Hypertensive Patients : The Non-Invasive Atherosclerotic Evaluation in Hypertension (NOAH) Study
• Renal Protective Effect in Hypertensive Patients : The High Doses of Angiotensin II Receptor Blocker (HARB) Study
• Renal-Protective Effect of T- and L-Type Calcium Channel Blockers in Hypertensive Patients : An Amlodipine-to-Benidipine Changeover (ABC) Study
• Variation in OSBPL10 is associated with dyslipidemia
• Gene-environmental interaction regarding alcohol-metabolizing enzymes in the Japanese general population
• PJ-618 Evaluation of 14 Genes Involved in Reverse Cholesterol Transport in the Japanese General Population(Genetics/Genetically engineered models/Gene therapy-4, The 71st Annual Scientific Meeting of the Japanese Circulation Society)
• High blood pressure worsens age-related increases in arterial stiffness evaluated by pulse wave velocity in subjects with lifestyle-related diseases
• PJ-032 Fas Ligand Expression Levels in Mononuclear Cells May Indicate the Degree of Improvement of Endothelial Function by Statin(Endothelium-5 (H) PJ6,Poster Session (Japanese),The 70th Anniversary Annual Scientific Meeting of the Japanese Circulation So
• Green Coffee Bean Extract Improves Human Vasoreactivity
• β3-Adrenergic Receptor Trp64arg Polymorphism Is Related with Endothelial Dysfunction via Increased Oxidized Stress in Proportion to Increasing Sympathetic Nervous Activity
• Intercellular Adhesion Molecule-1 G241R Polymorphism Influences Increasing Arterial Stiffness
• Single Nucleotide Polymorphisms of Ligand-Receptor System of Monocyte Chemoattractant Protein-1 Influence Different Arterial Dysfunctions with Serum Interleukin-15 Elevation
• Hypertension Attenuates the Efficacy of Hypoglycemic Therapy for Preserving Coronary Flow Reserve in Patients with Type 2 Diabetes
• Plasma levels of inflammatory related substances are correlated with severity of aortic stiffness and endothelial dysfunction in hypertensive patients
• Plasma level of 8-hydroxydeoxyguanosine, a marker of oxidative stress, was correlated to endothelial dysfunction in hypertensive patients
• Serum hepatocyte growth factor concentration is a specific marker of endothelial dysfunction in humans
• Low-Dose Doxazosin Imoroved Aortic Stiffness and Endothelial Dysfunction as Measured by Noninvasive Evaluation
• The role of sympathetic nervous activity in renal injury and end-stage renal disease
• Effects of hydroxyhydroquinone-reduced coffee on vasoreactivity and blood pressure
• Clinical Usefulness and Limitations of Brachial-Ankle Pulse Wave Velocity in the Evaluation of Cardiovascular Complications in Hypertensive Patients
• Evaluation of Morning Blood Pressure Elevation and Autonomic Nervous Activity in Hypertensive Patients Using Wavelet Transform of Heart Rate Variability
• Genetic Influences of β-Adrenoceptor Polymorphisms on Arterial Functional Changes and Cardiac Remodeling in Hypertensive Patients
• Impairment of Instantaneous Autonomic Regulation Relates to Blood Pressure Fall Immediately after Standing in the Elderly and Hypertensives
• ACE2 Mutant Mice Increase Cardiac Angiotensin II and Increase Incidence of Heart Failure in Response to Pressure Overload (Heart Failure, Basic 7 (M), The 69th Annual Scientific Meeting of the Japanese Circulation Society)
• Relationship of Bradykinin B2 Receptor Gene Polymorphism with Essential Hypertension and Left Ventricular Hypertrophy
• Association between Hepatocyte Growth Factor Gene Polymorphism and Essential Hypertension
• 4 Tailored Medicine for Hypertension and Cardiovascular Complications(Symposium 2 (SY2) (H) : Hypertension : From Molecular Mechanisms to Tailored Therapy)(Special Program)
• Single Nucleotide Polymorphisms in the Interleukin-6 Gene Associated with Blood Pressure and Atherosclerosis in a Japanese General Population
• Leptin-Receptor Polymorphisms Relate to Obesity through Blunted Leptin-Mediated Sympathetic Nerve Activation in a Caucasian Male Population
• PJ-042 Pivotal Roles of CYLD (cylindromatosis) as a Deubiquitinating Enzyme in Vasculature(Atherosclerosis, basic(05)(IHD),Poster Session(Japanese),The 72nd Annual Scientific Meeting of the Japanese Circulation Society)
• PE-347 Association of Hypoadiponectinemia with Smoking Habit in Men(Diabetes/Obesity/Metabolic syndrome-6 (H) PE58,Poster Session (English),The 70th Anniversary Annual Scientific Meeting of the Japanese Circulation Society)
• Plasma Adiponectin Concentration and Renal Function, and its Predictive Role in Cardiovascular Disease (Kidney/Renal Circulation 2 (H), The 69th Annual Scientific Meeting of the Japanese Circulation Society)
• Plasma Adiponectin and Adrenomedullin Levels in Peripheral Arterial Occlusive Disease(Peripheral Circulation/Vascular Disease 2 (H), The 69th Annual Scientific Meeting of the Japanese Circulation Society)
• SECRETORY MECHANISM AND PATHOPHYSIOLOGICAL ROLE OF HUMAN ATRIAL NATRIURETIC PEPTIDE IN MEN : Atrial Natriuretic Polypeptide (II) : PROCEEDINGS OF THE 50th ANNUAL SCIENTIFIC MEETING OF THE JAPANESE CIRCULATION SOCIETY
• OE-140 Impact of Diabetes and Chronic Kidney Disease on Preloadinduced Changes in Left Ventricular Diastolic Filling in Hypertensive Patients(Hypertension, clinical(01)(H),Oral Presentation(English),The 72nd Annual Scientific Meeting of the Japanese Circu
• Carotid Intima-Media Thickness Is Correlated with Impairment of Coronary Flow Reserve in Hypertensive Patients without Coronary Artery Disease
• High Plasma Norepinephrine Levels Associated with β2-Adrenoceptor Polymorphisms Predict Future Renal Damage in Nonobese Normotensive Individuals
• PE-555 Nail Mineral Microelement Analysis is Useful as an Intermediate Phenotype of Internal Environment in Cardiovascular Disease(Preventive medicine/Epidemiology/Education-4, The 71st Annual Scientific Meeting of the Japanese Circulation Society)
• β2- and β3-Adrenoceptor Polymorphisms Relate to Subsequent Weight Gain and Blood Pressure Elevation in Obese Normotensive Individuals
• Association between Angiotensin II Type 1 Receptor Gene Polymorphism and Essential Hypertension : the Ohasama Study
• FRS-158 Association of Beta1-adrenergic Receptor Gene Polymorphism with Cardiovascular Function in Japanese Population : the Ohasama Study(Hypertension (H) : FRS19)(Featured Research Session (English))
• Salt Sensitivity of Japanese from the Viewpoint of Gene Polymorphism
• OE-318 Geneic Variants of Adrenoceptors Play Key Roles in the Pathogenesis of Hypertension and Obesity(Hypertension, clinical-2 (H) OE54,Oral Presentation (English),The 70th Anniversary Annual Scientific Meeting of the Japanese Circulation Society)
• Association between senescence-related uncoupling protein 2 gene polymorphisms and abdominal obesity in Japanese subjects : The Tanno and Sobetsu study
• Gene Polymorphism of Myospryn (Cardiomyopathy-Associated 5) Is Associated with Left Ventricular Wall Thickness in Patients with Hypertension
• Association between PPAR γ polymorphism and hypertension in Japanese
• Effects of Antihypertensive Drugs and Gene Variants in the Renin-Angiotensin System
• Lack of Correlation between Mbo I Restriction Fragment Length Polymorphism of Renin Gene and Essential Hypertension in Japanese
• Association of Polymorphism in the Promoter Region of the Apolipoprotein E Gene with Diastolic Blood Pressure in Normotensive Japanese
• Polymorphism of myospryn is associated with left ventricular diastolic dysfunction
• -P118-ENDOTHELIN ENHANCES ADRENERGIC VASOCONSTRICTION IN RAT : Hypertension : FREE COMMUNICATIONS(III) : PROCEEDINGS OF THE 53th ANNUAL SCIENTIFIC MEETING OF THE JAPANESE CIRCULATION SOCIETY
• Lower Plasma Adiponectin Concentration Increases Risk for Hypertension
• C-Reactive Protein, Left Ventricular Mass Index, and Risk of Cardiovascular Disease in Essential Hypertension
• PE-454 Pulmonary Venous Ratio of Systolic to Diastolic Wave as a Predictor of Cardiovascular Disease in Essential Hypertension(Hypertension, clinical-05, The 71st Annual Scientific Meeting of the Japanese Circulation Society)
• PE-444 C-Reactive Protein in Essential Hypertension : Association with Left Ventricular Mass Index and Risk of Cardiovascular Disease(Hypertension, clinical-04, The 71st Annual Scientific Meeting of the Japanese Circulation Society)
• Effect of kihito extract granules on cognitive function in patients with Alzheimer's-type dementia
• A Novel Mouse Model for Type 2 Diabetes and Non-alcoholic Fatty Liver Disease : Spontaneous Amelioration of Diabetes by Augmented Beta Cell Mass
• 2 Estrogen Decreases the Activation of RANK-RANKL System in Vascular Calcification(Young Investigator's Award for International Students Finalists Lecture (YIA International),The 73rd Annual Scientific Meeting of The Japanese Circulation Society)
• OJ-195 Pivotal Roles of Deubiquitinating Enzymes UCHL1, HAUSP, and CYLD in Vasculature as an Anti-proliferative and Anti-inflammatory Effect(Atherosclerosis, basic-3, The 71st Annual Scientific Meeting of the Japanese Circulation Society)
• PJ-098 Ubiquitin C-terminal Hydroxylase L1 (UCHL1), the Causative Genes of Inherited Parkinson's Disease, Has an Anti-inflammatory Action in Endothelial Cells(Molecular biology, vascular-3 (H) PJ17,Poster Session (Japanese),The 70th Anniversary Annual Sci
• Klotho gene delivery suppresses oxidative stress in vivo
• -P121-ENDOTHELIN INHIBITS RENIN RELEASE FROM ISOLATED RAT GLOMERULI : Hypertension : FREE COMMUNICATIONS(III) : PROCEEDINGS OF THE 53th ANNUAL SCIENTIFIC MEETING OF THE JAPANESE CIRCULATION SOCIETY
• PJ-125 A Polymorphism in the Promoter of Angiotensinogen Gene is Associated with Adipose Tissue Distribution in Japanese : the Sobetsu Study(Hypertension, Clinical 3 (H) : PJ21)(Poster Session (Japanese))
• Tissue Inhibitor of Metalloproteinase-3 Deficiency Inhibits Blood Pressure Elevation and Myocardial Microvascular Remodeling Induced by Chronic Administration of N^ω-Nitro-L-Arginine Methyl Ester in Mice
• Tissue Inhibitor of Metalloproteinase-3 Plays Important Roles in the Kidney Following Unilateral Ureteral Obstruction
• Intracellular Ca^-elevation Plays a Crucial Role in the PKC-independent Antagonizing Effect of Angiotensinll against Insulin-induced Production of PI(3, 4, 5)P3 in Cardiomyocytes (Molecular Biology, Myocardium 2 (M), The 69th Annual Scientific Meeting
• Rho GTPase Activating Protein 8 Gene Polymorphism and Genetic Predisposition to Hypertension : the Tanno Sobetsu Study (Genetics/Genetically Engineered Models (H), The 69th Annual Scientific Meeting of the Japanese Circulation Society)
• Enhancement of Oxidant Stress and Collagen Synthesis at Acute Worsening of Chronic Heart Failure(Heart Failure, Clinical 17 (M), The 69th Annual Scientific Meeting of the Japanese Circulation Society)
• Anti-oxidant Defense Systems Attenuate the Enhanced Collagen Synthesis in Patients with Acute Worsening of Chronic Heart Failure(Heart Failure, Clinical 17 (M), The 69th Annual Scientific Meeting of the Japanese Circulation Society)
• Clinical Efficacy of a New Angiotensin II Type 1 Receptor Blocker, Pratosartan, in Hypertensive Patients
• Exercise-induced acute kidney injury with reversible posterior leukoencephalopathy syndrome
• 2 Mineral and Bone Disorder in Cardio-renal Interaction(The Mechanism and Management of Cardio-renal Risk,Roundtable Discussion 3 (RT-3) (H),The 73rd Annual Scientific Meeting of The Japanese Circulation Society)
• The Role of Endothelial Cells in the Insulin-Mediated Vascular Cell Proliferation
• The counterregulating role of ACE2 and ACE2-mediated angiotensin 1-7 signaling against angiotensin II stimulation in vascular cells
• Strong suppression of the renin-angiotensin system has a renal-protective effect in hypertensive patients : High-dose ARB with ACE inhibitor (Hawaii) study
• Development of Novel High Throughput Functional Screening System Based on HVJ-E Vector : Screening of Anti-vascular Remodeling Factor in Hypertension(Hypertension, Basic 2 (H), The 69th Annual Scientific Meeting of the Japanese Circulation Society)
• Comparison of strict- and mild-blood pressure control in elderly hypertensive patients : a per-protocol analysis of JATOS
• 3 On-going Japanese Clinical Trials for Hypertension : What Evidence We Need in Aging and Metabolic Era(ESC-JCS Joint Symposium (ESC-JCS Joint Symposium) (H) Evidence-Based Medical Treatment of Hypertension,Special Program,The 72nd Annual Scientific Meeti
• Association of carotid atherosclerosis with genetic polymorphisms of the klotho gene in patients with hypertension
• 4 Treatment of Very Elderly Patients with Arrhythmia : From the Point of Geriatric Medicine(Indication of Invasive Cardiovascular Treatment in the Very Elderly,Roundtable Discussion 1 (RT-1) (IHD),The 73rd Annual Scientific Meeting of The Japanese Circula
• What Is the Goal of Antihypertensive Treatment in Very Elderly People?
• Angiotensin-converting enzyme single nucleotide polymorphism is a genetic risk factor for cardiovascular disease : a cohort study of hypertensive patients

もっと見る 閉じる

スポンサーリンク