Endogenous Prostaglandins in Experimental Myocardial Infarction in Canines : The role of released PGE_1 and PGF_2α in the regulation of coronary blood flow after coronary artery occlusion : English Summaries of Original Articles written in Japanese

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概要

• 論文の詳細を見る

• A significant release of PGE_1 and PGF_<2α> from the ischemic area of the myocardium 15 min after the ligation of LAD was demonstrated. The coronary venous blood flow in the ischemic area significantly decreased 5 min and significantly increased 15 min after ligation. In the indomethacin pretreated group. there was no release of PGE_1 and PGF_<2α>; the coronary venous blood flow decreased 5 min and no increase was found 15 min after ligation. A significant release of lactate after ligation was demonstrated in both of the IND and non-IND groups. However, the release ratio was significantly greater in the IND group than in the non-IND group. Thus, it is suggested that prostaglandins (especially PGE_1 ) play an important role in the regulation of coronary blood flow in the ischemic myocardium and in myocardial metabolism at an early stage of acute myocardial infarction.

• 社団法人日本循環器学会の論文
• 1981-12-20

著者

• Ogawa Kouichi

  Meijo Hospital

• HASHIMOTO Hidekazu

  The second Depertment of Internal Medicine,Nagoya University School of Medicine

• Satake Tatsuo

  The Second Department Of Internal Medicine Nagoya University School Of Medicine

• Ito Takayuki

  The Second Department of Internal Medicine, Nagoya University School of Medicine

• OGAWA KOUICHI

  The Second Department of Internal Medicine, Nagoya University School of Medicine

• Ogawa Kouichi

  Second Department Of Internal Medicine Nagoy University School Of Medicine

• ENOMOTO ISSEI

  The Second Department of internal Medicine, Nagoya University School of Medisine

• KAI ISSEI

  The Second Department of internal Medicine, Nagoya University School of Medisine

• SAKAI KAZUYOSHI

  The Second Department of internal Medicine, Nagoya University School of Medisine

• Enomoto Issei

  The Second Department Of Internal Medicine Nagoya University School Of Medisine

• Sakai Kazuyoshi

  The 2nd Dept. Of Internal Medicine Nagoya University School Of Medicine

• Hashimoto H

  名古屋大学 第2内科

• Ogawa Kouichi

  The Second Department Of Internal Medicine Nagoya University School Of Medicine

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