Endogenous Prostaglandins in Experimental Myocardial Infarction in Canines : The role of released PGE_1 and PGF_2α in the regulation of coronary blood flow after coronary artery occlusion : English Summaries of Original Articles written in Japanese
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概要
- 論文の詳細を見る
A significant release of PGE_1 and PGF_<2α> from the ischemic area of the myocardium 15 min after the ligation of LAD was demonstrated. The coronary venous blood flow in the ischemic area significantly decreased 5 min and significantly increased 15 min after ligation. In the indomethacin pretreated group. there was no release of PGE_1 and PGF_<2α>; the coronary venous blood flow decreased 5 min and no increase was found 15 min after ligation. A significant release of lactate after ligation was demonstrated in both of the IND and non-IND groups. However, the release ratio was significantly greater in the IND group than in the non-IND group. Thus, it is suggested that prostaglandins (especially PGE_1 ) play an important role in the regulation of coronary blood flow in the ischemic myocardium and in myocardial metabolism at an early stage of acute myocardial infarction.
- 社団法人日本循環器学会の論文
- 1981-12-20
著者
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Ogawa Kouichi
Meijo Hospital
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HASHIMOTO Hidekazu
The second Depertment of Internal Medicine,Nagoya University School of Medicine
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Satake Tatsuo
The Second Department Of Internal Medicine Nagoya University School Of Medicine
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Ito Takayuki
The Second Department of Internal Medicine, Nagoya University School of Medicine
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OGAWA KOUICHI
The Second Department of Internal Medicine, Nagoya University School of Medicine
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Ogawa Kouichi
Second Department Of Internal Medicine Nagoy University School Of Medicine
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ENOMOTO ISSEI
The Second Department of internal Medicine, Nagoya University School of Medisine
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KAI ISSEI
The Second Department of internal Medicine, Nagoya University School of Medisine
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SAKAI KAZUYOSHI
The Second Department of internal Medicine, Nagoya University School of Medisine
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Enomoto Issei
The Second Department Of Internal Medicine Nagoya University School Of Medisine
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Sakai Kazuyoshi
The 2nd Dept. Of Internal Medicine Nagoya University School Of Medicine
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Hashimoto H
名古屋大学 第2内科
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Ogawa Kouichi
The Second Department Of Internal Medicine Nagoya University School Of Medicine
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