慢性蕁麻疹の研究アトピー性及び心因性要因の素質的差異

概要

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Dilution threshold of skin reaction to the solutions of histamine and compound 48/80 were determined on the patients of chronic urticaria, asthma as well as normal subjects. The results show that the patients of chronic urticaria are markedly hypersensitive to histamine and compound 48/80 injected into the skin, meanwhile asthmatic patients reacted mostly as same as normal subjects. The cause of hypersensitivity in the patients of chronic urticaria is considered not to be due to the increase of histamine release from the skin tissue. Through the testing by Yatabe-Gilford questionaire, chronic urticaria due to psycho-somatic factor showed a different pattern from the usual type;the former showed a psychological disturbance, but the latter appeared almost normal. In addition, patients of psycho-somatic type showed nearly normal sensitivity to histamine.
日本アレルギー学会の論文
1968-07-31