室内塵とダニとの抗原性の一致について : 第1報.Dermatophagoides farinae, hughes, 1961(Acarina Psoroptidae)(コナヒョウヒダニ)を用いての臨床的な検討.

概要

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One of house dust mites, D.farinae was cultured and the extract was made in an attemption to compare the antigenic identity with the commercially available house dust antigen since house dust mites were always found in house dust. Two fold dilution was made from 1:1,000 dilution of the house dust extract and from 1:10,000 of the D.farinae extract. Intracutaneous skin test was carried out in eighty nine subjects and the end point of skin reactivity was compared between both extracts. Very close correlation was found between them (correlation coefficient was 0.813)and the majority of antigenic substance was identified in inside fluid of D.farinae extract after dialysis. The extract of excretes or secretes of D.farinae demonstrated very close correlation with body extract of D.farinae in skin test(correlation coefficient was 0.958). All asthmatic subjects with positive inhalative provocative test with house dust extract(six subjects so far)were also positive to the provocative inhalation test with D.farinae extract. From the result of skin test and inhalation test, D.farinae appears to be the most important antigenic substance contained in house dust.
日本アレルギー学会の論文
1968-02-28