A13-106 DOUBLE SPRING NANO-MOLECULAR MACHINE MODEL (DS-NMM) USING THERMAL FLUCTUATION AND CHEMICAL ENERGY

概要

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A novel Nano-Molecular Machine Model (DS-NMM) was proposed in order to further the understanding of the movement of the actin-myosin system in muscle. DS-NMM is comprised of numerous inclined rods extending from a central body in a manner similar to myosin; furthermore, its movement is forward in one direction upon independent vibration of these rods. DS-NMM can convert thermal noise to unidirectional motion employing stochastic resonance and inclined rods in random open fields. Concrete estimates were obtained of the physical characteristics of DS-NMM as a conceptual model of the actin-myosin system. When DS-NMM displays radius of 5nm and mass of 10^<-21>kg, which are characteristic of a myosin molecule, the estimated frequency of stochastic resonance closely approaches phonon frequency, 10^<11> rad/s. The amplitude of stochastic resonance is 2×10^<-11>m. Moreover, physical work of this machine is approximately 10^<-18> joules, which is nearly equal to the energy output generated upon hydrolysis of one ATP molecule (10^<-10> N/head). We concluded that the actin-myosin system in muscle derives its movement from the random motion of water molecules
一般社団法人日本機械学会の論文
2003-11-30