Introduction of human gadd45 gene to human immortal cell lines using the inducible expression vector

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概要

• 論文の詳細を見る
• 日本放射線影響学会の論文

著者

• Kodama Seiji

  Div. Radiat. Biol. , Fac. Pharm. Sci. , Nagasaki Univ.

• Watanabe Masami

  Div. Radiat. Biol. , Fac. Pharm. Sci. , Nagasaki Univ.

• ISHIZAKI Kanji

  Central Laboratory and Radiation Biology, Aichi Cancer Center Research Institute

• SUZUKI Keiji

  Div. Radiat. Biol. , Fac. Pharm. Sci. , Nagasaki Univ.

• Kodama Seiji

  Division Of Radiation Biology And Health Science Research Center For Radiation And Radioisotopes Res

• Kodama Seiji

  Div. Radial Biol. Dept. Health. Sci. Fac. Pani. Sci. Nagasaki Univ.

• Hamano Hiroki

  Division Of Radiation Biology Department Of Radiology And Radiation Biology Course Of Life Sciences

• 石崎 寛治

  Central Laboratory And Radiation Biology Aichi Cancer Center Research Institute

• Ishizaki Kanji

  Central Laboratory And Radiation Biology Research Institute Aich Cancer Center

• Ishizaki K

  Central Laboratory And Radiation Biology Aichi Cancer Center Research Institute

• Ishizaki Kanji

  Laboratory Of Experimental Radiology Aichi Cancer Center

• Ishizaki Kanji

  大阪府立大学先端科学イノベーションセンター 放射線生命科学

• Inoue Satomi

  Div. Radiat. Biol. Fac. Pharm. Sci. Nagasaki Univ.

• HASHIMOTO Hirokazu

  Div. Radiat. Biol. , Fac. Pharm. Sci. , Nagasaki Univ.

• ISHIZAKI Kanji

  Dept. Radiat. , Aichi Cancer Inst.

• Watanabe Masami

  Div. Radait. Biol. Fac. Phami. Sci. Nagasaki Univ.

• INOUE Satomi

  Div. Radiat. Biol. , Fac. Pharm. Sci. , Nagasaki Univ.

• KODAMA Seiji

  Div. RadiaL Biol. , Dept. Health. Sci. , Fac. Pani. Sci. , Nagasaki Univ.

• WATANABE Masami

  Div. Radait. Biol. , Fac. Phami. Sci. , Nagasaki Univ.

関連論文

• Changes in the Sensitivity of Intratumor Cells during Fractionated Tirapazamine Administration
• Usefulness of Tirapazamine as a Combined Agent in Chemoradiation and Thermo-chemoradiation Therapy at Mild Temperatures: Reference to the Effect on Intratumor Quiescent Cells
• AT Cells Show Dissimilar Hypersensitivity to Heavy-Ion and X-rays Irradiation
• X-ray sensitivity of human cells formed a mulLicellular spheroid.
• AT Cells Show Dissimilar Hypersensitivity to Heavy-Ion and X-rays Irradiation
• The Mechanism of Increase in Drug Resistance in Polyploid Hamster Cells Induced by Cell Cycle-Perturbing Agents
• Transient DNA inhibition produces proliferative tetraploid W9 cells which have both increased drug resistance and genomic instability with a propensity for gene amplification
• Genetic Instability Induced by Cell Cycle Arrest at S Phase in V79 Cells
• Potentially Lethal Damage Repair by Total and Quiescent Tumor Cells Following Various DNA-damaging Treatments
• Enhancement of Cisplatin Sensitivity of Quiescent Cells in Solid Tumors by Combined Treatment with Tirapazamine and Low-Temperature Hyperthermia
• Genetical instability induced by low doses of radiations
• A Comparison of Biological Responses of Human Tumor Cells After Irradiation with Heavy Ions and Neutrons
• Effective Suppression of Bystander Effects by DMSO Treatment of Irradiated CHO Cells
• Responses of total and quiescent cell populations in solid tumors to carbon ion beam irradiation (290 MeV/u) in vivo
• 食道がんリスクに関するALDH2、CYP2E1、飲酒の遺伝子環境交互作用
• Absence of G1 arrest after X-ray irradiation in cancer cells with wild-type p53
• Biological effect of radiation-induced long life radicals
• The induction and the fate of chromosome aberrations by ionizing radiation in human fibroblast cells
• Analysis of X-ray-induced chromosome aberrations in human embryonic fibroblasts used by FISH
• Changes in the Pharmacokinetics of Gd-DTPA in Experimental Tumors after Charged Particle Radiation : Comparison with γ-Ray Radiation
• Repair of Skin Damage During Fractionated Irradiation with Gamma Rays and Low-LET Carbon Ions
• Biological Gain of Carbon-ion Radiotherapy for the Early Response of Tumor Growth Delay and against Early Response of Skin Reaction in Mice
• 269 Significance of beta term in carbon-ion radiotherapy(Bases of radiotherapy, Abstracts of the 46th Annual Meeting of the Japan Radiation Research Society)
• 265 Relationship between RBE values of Carbon Ion and Tumor Growth Rate(Bases of radiotherapy, Abstracts of the 46th Annual Meeting of the Japan Radiation Research Society)
• Effect of Space Flight on the Frequency of Micronuclei and Expression of Stress-responsive Proteins in Cultured Mammalian Cells
• No Induction of p53 Phosphorylation and Few Focus Formation of Phosphorylated H2AX Suggest Efficient Repair of DNA Damage During Chronic Low-dose-rate Irradiation in Human Cells
• 28 AT cells in GI phase are sensitive to low dose rate radiation(Low dose and low dose-rate effects, Abstracts of the 46th Annual Meeting of the Japan Radiation Research Society)
• Genetic effect of low dose rate radiation on human cells immortalized by introducing the hTERT gene
• Establishment of Immortal Normal and Ataxia Telangiectasia Fibroblast Cell Lines by Introduction of the hTERT Gene
• Genetic Effect of Low-Dose-Rate Radiation on Human Immortal Cells
• Introduction of a Normal Human Chromosome 8 Corrects Abnormal Phenotypes of Werner Syndrome Cells Immortalized by Expressing an hTERT Gene
• 226 Radiation-induced delayed chromosomal instability caused by large deletion(Genetic instability, Abstracts of the 46th Annual Meeting of the Japan Radiation Research Society)
• 223 Radiation-Induced Delayed Chromosomal Instability(Genetic instability, Abstracts of the 46th Annual Meeting of the Japan Radiation Research Society)
• 221 A Role of DNA Double Strand Break Repair in the Induction of Genetic Instability(Genetic instability, Abstracts of the 46th Annual Meeting of the Japan Radiation Research Society)
• 214 The complementation of abnormal phenotypes of Werner syndrome cells by expressing WRN gene(Physics, chemistry and DNA damage, Abstracts of the 46th Annual Meeting of the Japan Radiation Research Society)
• S-2-3 Radiation-Induced Delayed Chromosome Aberrations(Radiation Induced Genetical Instability : What Is the Mechanism That a Cell Memorizes Being Irradiated?, Abstracts of the 46th Annual Meeting of the Japan Radiation Research Society)
• Instability of a Human Chromosome Exposed to Radiation in Unirradiated Mouse Cells
• The Role of DNA-PKcs Function on Induction of Genetic Instability by Radiation
• Radiation-induced genomic instability caused by large deletion (position)
• Thermosensitization by Inhibition of Gap Junctional Intercellular Communication
• Effects of strong static magnetic field on instability of microsatellite sequences in human cells.
• L-myc Genotype is Associated with Different Susceptibility to Lung Cancer in Smokers
• Different Susceptibility of Each L-myc Genotype to Esophageal Cancer Risk Factors
• 225 Influence of Reactive Oxygen Species in the Induction of Genetic Instability by Radiation(Genetic instability, Abstracts of the 46th Annual Meeting of the Japan Radiation Research Society)
• 222 X-ray-induced genomic instability in Atm knock-out mouse cells(Genetic instability, Abstracts of the 46th Annual Meeting of the Japan Radiation Research Society)
• 220 Mechanism of radiation-induced delayed mutagenesis(Genetic instability, Abstracts of the 46th Annual Meeting of the Japan Radiation Research Society)
• 217 Localization of Phosphorylated H2AX and Phosphorylated p53 in Cells Inducing X-ray-induced Senescence-like Growth Arrest(Physics, chemistry and DNA damage, Abstracts of the 46th Annual Meeting of the Japan Radiation Research Society)
• 168 Mechanism of cell cycle-dependent cell death by heat shock(Radio-protection and sensitization, Abstracts of the 46th Annual Meeting of the Japan Radiation Research Society)
• 141 The role of site-specific phosphorylation on X-ray-induced p53 accumulation(Redox regulation, Abstracts of the 46th Annual Meeting of the Japan Radiation Research Society)
• Mechanisms of cell death by heat
• Induction of chromosome aberrations by a combined treatment with radiation and heat
• Genetic Instability Induced by Hypogravity or Hypergravity in Human Cells
• Mutations induced in Drosophila during space flight
• Mutations Induced in Drosophila during Space Flight (特集:日本の宇宙生物学実験)
• Genetic effects of space radiation in Drosophila melanogasrer II. Somatic mutations.
• Genetic effects of space radiation in Drosophila melanogaster I. Sex-linked recessive lethal mutations.
• 104 DNA Damage-Induced Phosphorylation of Histone H2AX and Alteration of Chromatin Structure(Repair of radiation damage, Abstracts of the 46th Annual Meeting of the Japan Radiation Research Society)
• 97 A Role of WRN Protein in the Recovery from DNA Replication Arrest(Repair of radiation damage, Abstracts of the 46th Annual Meeting of the Japan Radiation Research Society)
• Involvement of reactive oxygen species (ROS) in the induction of genetic instability by radiation
• Relationship between dysfunction of WRN protein and radiosensitivity
• Role of WRN exonuclease in repair of DNA double strand breaks
• Molecular analysis of mutations at the hprt locus in Werner syndrome cells by multiplex PCR
• Mechanism of radiation-induced delayed mutagenesis
• Delayed Induction of DNA Damage and Activation of p53 in X-ray Surviving Cells
• Participation of ATM function in X-ray-induced delayed chromosomal instability
• Biological Action of Curcumin on Transformed Mouse Cells
• Biological Action of Curcumin on Transformed Mouse Cells
• Role of Ser15, Thr18, and Ser20 phosphorylation in p53 stabilization after X-irradiation
• X-rays-induced phosphorylation of H2AX in mitotic cells
• The role of telomerase activity in the radiation carcinogenesis processes of normal human cells
• Genetic effect of space flight of the 9-day space shuttle mission on cultured human cells
• The Effects of Static Magnetic Fields and X-rays on Instability of Microsatellite Repetitive Sequences
• Detection of X-ray induced genetic changes in human cells by using microsatellite and minisatellite sequences.
• Introduction of human gadd45 gene to human immortal cell lines using the inducible expression vector
• 211 Effect of RibCys on scavenging long-lived radicals and reducing gene mutation in mammalian cells by adding AFTER irradiation(Physics, chemistry and DNA damage, Abstracts of the 46th Annual Meeting of the Japan Radiation Research Society)
• 食道がんとミトコンドリアゲノムの変異 (特集 ミトコンドリアゲノムと癌)
• テロメラーゼ遺伝子導入によるヒト細胞の不死化
• Isolation of Human Exonuclease 1 homolog CDNA from the chicken B cell line DT40
• ヒト細胞におけるDNAミスマッチ修復の反応機構とそれに関与する遺伝子群
• ヒトのDNAミスマッチ修復因子hMLH1と相互作用する蛋白質の単離・同定
• Mismatch repair deficiency in human esophageal cancer cells
• Mechanisms of cell death by heat
• The number of Platinum Atoms Binding to DNA Molecules in SHOK Cells Transformed by Various Oncogenes Treated with ^mPt-cis-Diammine-dicliloroplatinum
• The effect of antisense fibronectin gene expression on human cells.
• Cellular response and p53 accumulation following heat shock in normal human cells
• The effect of adaptive response on radiation-induced genetic instability
• Radiation-induced genetic instability in mouse m5S cells
• Role of heat-shock protein 72 on expression of malignant phenotypes in cancer cells.
• Effect of low dose radiation on in vitro life span of human embryo cells
• Genomic Instability by Mismatch Repair Abnormality
• Role of Gadd45 gene in X-ray-induced G_1 arrest in human cells
• Function of the introduced gadd45 gene in ataxia telangiectasia cells
• Determination of Transforming Sequence in Human Bronchial Epitbelial Cells Malignantly Ttansformed by Radon-Simulated a-Particles
• Changes of malignant phenotyps in human canncer cells transfected with antisense-human hsp72 gene.
• Role of phosphorylation of p53 protein at serine 15 in normal human embryonic cells irradiated with X-rays
• Overexpression of HSP72 related to malignantey of human cancer cells
• Heat treatment induces condensation and disintegration of nuclei but not apoptosis
• Phosphorylation and ubiquitination of p53 protein in normal human embryonic cells irradiated with X-rays
• Sensors and signal transduction pathways involving p53 protein accumulation in normal human embryonic cells irradiated with X-rays
• Activation of signal transduction pathways and p53-dependent pathway by X-rays in normal human embryonic cells

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