Genetical instability induced by low doses of radiations

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概要

• 論文の詳細を見る
• 日本放射線影響学会の論文

著者

• Kodama Seiji

  Div. Radiat. Biol. , Fac. Pharm. Sci. , Nagasaki Univ.

• Watanabe Masami

  Div. Radiat. Biol. , Fac. Pharm. Sci. , Nagasaki Univ.

• Kinashi Yuko

  Radiation Safety And Control Research Reactor Institute Kyoto University

• MIYAKE Mieko

  Div. Radiat. Biol. , Fac. Pharm. Sci. , Nagasaki Univ.

• SUZUKI Keiji

  Div. Radiat. Biol. , Fac. Pharm. Sci. , Nagasaki Univ.

• SUZUK Masao

  Natl. Inst. Radiol. Sci.

• KASE Youko

  Natl. Inst. Radiol. Sci.

• SUGAHARA Tsutomu

  Health Res. Fond.

• Kodama Seiji

  Division Of Radiation Biology And Health Science Research Center For Radiation And Radioisotopes Res

• Kodama Seiji

  Div. Radial Biol. Dept. Health. Sci. Fac. Pani. Sci. Nagasaki Univ.

• Miyake Mieko

  Lab. Radiat. And Life Sci. Schl. Pharm. Sci. Nagasaki Univ.

• Suzuki Masao

  Heavy-ion Radiobiology Res. Group National Inst. Radiological Sciences

• Kinashi Yuko

  Kyoto Univ. Research Rcactor Institute

• Mori Masako

  Lab. Radiat. &life Sci. Schl. Pharm. Sci. Nagasaki Univ.

• Morita Makiko

  Lab. Radiat. And Life Sci. Schl. Pharm. Sci. Nagasaki Univ.

• Watanabe Masami

  Div. Radait. Biol. Fac. Phami. Sci. Nagasaki Univ.

• KODAMA Seiji

  Div. RadiaL Biol. , Dept. Health. Sci. , Fac. Pani. Sci. , Nagasaki Univ.

• WATANABE Masami

  Div. Radait. Biol. , Fac. Phami. Sci. , Nagasaki Univ.

関連論文

• Radiation Biology of Caenorhabditis elegans : Germ Cell Response, Aging and Behavior
• Impact of the p53 Status of the Tumor Cells on the Effect of Reactor Neutron Beam Irradiation, with Emphasis on the Response of Intratumor Quiescent Cells
• Effects of p53 Status on Radiosensitivity and the Size of Hypoxic Fraction of Intratumor Total and QuiescentCell Populations
• Evaluation of the Potential of p-Boronophenylalaninol as a Boron Carrier in Boron Neutron Capture Therapy, Referring to the Effect on Intratumor Quiescent Cells
• The Effects of Boron Neutron Capture Therapy on Liver Tumors and Normal Hepatocytes in Mice
• The Combined Effect of Electroporation and Borocaptate in Boron Neutron Capture Therapy for Murine Solid Tumors
• Changes in the Sensitivity of Intratumor Cells during Fractionated Tirapazamine Administration
• Usefulness of Tirapazamine as a Combined Agent in Chemoradiation and Thermo-chemoradiation Therapy at Mild Temperatures: Reference to the Effect on Intratumor Quiescent Cells
• Augmentation in Chemosensitivity of Intratumor Quiescent Cells by Combined Treatment with Nicotinamide and Mild Hyperthermia
• Determination and Drug Modification Assessed by Micronucleus Frequency Assay of Potentially Lethal Damege Repair in Quiescent Cell Populations within Murine Solid Tumors
• X-ray sensitivity of human cells formed a mulLicellular spheroid.
• 硼素中性子捕捉療法時の患部近傍での放射化の評価
• Recent Advances in the Biology of Heavy-Ion Cancer Therapy
• γ-ray Irradiation Enhanced Boron-10 Compound Accumulation in Murine Tumors
• A Simple and Rapid Method for Measurement of ^B-para-Boronophenylalanine in the Blood for Boron Neutron Capture Therapy Using Fluorescence Spectrophotometry
• Evaluation of Hypoxia-specific Cytotoxic Bioreductive Agent-sodium Borocaptate-^B Conjugates as ^B-carriers in Boron Neutron Capture Therapy
• S-4-4 From Regionally Selective Radiotherapy to Cellular Selective Radiotherapy(Aiming Further Development of Radiotherapy, Abstracts of the 46th Annual Meeting of the Japan Radiation Research Society)
• Usefulness of Hexamethylenetetramine as an Adjuvant to Radiation and Cisplatin in the Treatment of Solid Tumors : its Independency of p53 Status
• Potentially Lethal Damage Repair by Total and Quiescent Tumor Cells Following Various DNA-damaging Treatments
• Enhancement of Cisplatin Sensitivity of Quiescent Cells in Solid Tumors by Combined Treatment with Tirapazamine and Low-Temperature Hyperthermia
• Resistance to ^Pt-radiolabeled cis-Diaminedichloroplatinum (II) of SHOK Cells Transfected with Various Oncogenes
• Cell-killing Efficiency and Number of Platinum Atoms Binding to DNA, RNA and Protein Molecules of HeLa Cells Treated with Combinations of trans-Diaminedichloroplatinum (II) and Hyperthermia
• Relationship between Cell-killing Efficiency and Number of Platinum Atoms Binding to DNA, RNA, and Protein Molecules in HeLa Cells Treated with cis -Diamine (glycolato) platinum (II)
• Genetical instability induced by low doses of radiations
• Mutagenic effects of restriction enzymes in Chinese hamstcr cells
• Proliferation and cell death of human glioblastoma cells after carbon-ion beam exposure : Morphologic and morphometric analyses
• Radiation response mechanisms of the extremely radioresistant bacterium Deinococcus radiodurans
• 109 Disruption Analysis of the recF Gene in the Radioresistant Bacterium Deinococcus radiodurans(Repair of radiation damage, Abstracts of the 46th Annual Meeting of the Japan Radiation Research Society)
• Detection of DNA strand breaks with PprA protein from the radioresistant bacterium Deinococcus radiodurans
• Inhibition of repair of radiation-induced damage by mild temperature hyperthermia, referring to the effect on quiescent cell populations
• Effective Suppression of Bystander Effects by DMSO Treatment of Irradiated CHO Cells
• Evaluation of Micronucleus Induction in Lymphocytes of Patients Following Boron-Neutron-Capture-Therapy : A Comparison with Thyroid Cancer Patients treated with radioiodine
• 84 Effects of Mild Temperature Hyperthermia and p53 Status of Tumor Cells on the Size of Hypoxic Cell Fractions in Solid Tumors(Radiation sensitivities in cells & tissues, Abstracts of the 46th Annual Meeting of the Japan Radiation Research Society)
• Effects of p53 Status and Wortmannin Treatment on Potentially Lethal Damage Repair, with Emphasis on the Response of Intratumor Quiescent Cells
• Usefulness of combined treatment with mild temperature hyperthermia and/or tirapazamine in the treatment of solid tumors : its independence of p53 status
• Development of Selective Irradiation Method to Blood Vessel
• Targeted Heavy-Ion Microbeam Irradiation of the Embryo But Not Yolk in the Diapause-Terminated Egg of the Silkworm, Bombyx mori, Induces The Somatic Mutation
• Locomotion - Learning Behavior Relationship in Caenorhabditis elegans Following γ-Ray Irradiation
• Exploration of 'Over Kill Effect' of High-LET Ar-and Fe-ions by Evaluating the Fraction of Non-hit Cell and Interphase Death
• Heavy-Ion Microbeam System at JAEA-Takasaki for Microbeam Biology
• Why Does Hemocyte Density Rise during the Wandering Stage of the Silkworm, Bombyx mori?
• Regeneration of Hemopoietic Organs in the Silkworm, Bombyx mori, After Locally Targeted Irradiation with Heavy Ion Beams
• 226 Radiation-induced delayed chromosomal instability caused by large deletion(Genetic instability, Abstracts of the 46th Annual Meeting of the Japan Radiation Research Society)
• 223 Radiation-Induced Delayed Chromosomal Instability(Genetic instability, Abstracts of the 46th Annual Meeting of the Japan Radiation Research Society)
• 221 A Role of DNA Double Strand Break Repair in the Induction of Genetic Instability(Genetic instability, Abstracts of the 46th Annual Meeting of the Japan Radiation Research Society)
• 214 The complementation of abnormal phenotypes of Werner syndrome cells by expressing WRN gene(Physics, chemistry and DNA damage, Abstracts of the 46th Annual Meeting of the Japan Radiation Research Society)
• S-2-3 Radiation-Induced Delayed Chromosome Aberrations(Radiation Induced Genetical Instability : What Is the Mechanism That a Cell Memorizes Being Irradiated?, Abstracts of the 46th Annual Meeting of the Japan Radiation Research Society)
• Instability of a Human Chromosome Exposed to Radiation in Unirradiated Mouse Cells
• The Role of DNA-PKcs Function on Induction of Genetic Instability by Radiation
• Radiation-induced genomic instability caused by large deletion (position)
• Thermosensitization by Inhibition of Gap Junctional Intercellular Communication
• Effects of Locally Targeted Heavy-ion and Laser Microbeam on Root Hydrotropism in Arabidopsis thaliana
• THE EFFECTS OF ULTRAVIOLET IRRADIATION AND HYPOXIA ON EXPRESSION OF GLUTATHIONE PEROXIDASE AND GLYCERALDEHYDE 3-PHOSPHATE DEHYDROGENASE IN THE CULTURED RETINAL PIGMENT EPITHELIUM
• ガンマ線照射後器官培養された豚眼毛様体上皮におけるアポトーシス
• 225 Influence of Reactive Oxygen Species in the Induction of Genetic Instability by Radiation(Genetic instability, Abstracts of the 46th Annual Meeting of the Japan Radiation Research Society)
• 222 X-ray-induced genomic instability in Atm knock-out mouse cells(Genetic instability, Abstracts of the 46th Annual Meeting of the Japan Radiation Research Society)
• 220 Mechanism of radiation-induced delayed mutagenesis(Genetic instability, Abstracts of the 46th Annual Meeting of the Japan Radiation Research Society)
• 217 Localization of Phosphorylated H2AX and Phosphorylated p53 in Cells Inducing X-ray-induced Senescence-like Growth Arrest(Physics, chemistry and DNA damage, Abstracts of the 46th Annual Meeting of the Japan Radiation Research Society)
• 168 Mechanism of cell cycle-dependent cell death by heat shock(Radio-protection and sensitization, Abstracts of the 46th Annual Meeting of the Japan Radiation Research Society)
• 141 The role of site-specific phosphorylation on X-ray-induced p53 accumulation(Redox regulation, Abstracts of the 46th Annual Meeting of the Japan Radiation Research Society)
• Mechanisms of cell death by heat
• Induction of chromosome aberrations by a combined treatment with radiation and heat
• Effects of Ionizing Radiation on Locomotory Behavior and Mechanosensation in Caenorhabditis elegans
• Vanguards of Paradigm Shift in Radiation Biology: Radiation-Induced Adaptive and Bystander Responses
• 104 DNA Damage-Induced Phosphorylation of Histone H2AX and Alteration of Chromatin Structure(Repair of radiation damage, Abstracts of the 46th Annual Meeting of the Japan Radiation Research Society)
• 97 A Role of WRN Protein in the Recovery from DNA Replication Arrest(Repair of radiation damage, Abstracts of the 46th Annual Meeting of the Japan Radiation Research Society)
• Effect of Locally Targeted Carbon-Ion Microbeam Irradiation on Learning Behavior in Caenorhabditis elegans
• Radiation-Quality Dependent Bystander Effects Induced in Normal Human Fibroblasts by X-ray, Proton and Heavy-Ion Microbeams
• Involvement of reactive oxygen species (ROS) in the induction of genetic instability by radiation
• Microbeam Irradiation Facilities for Radiobiology in Japan and China
• Relationship between dysfunction of WRN protein and radiosensitivity
• Role of WRN exonuclease in repair of DNA double strand breaks
• Molecular analysis of mutations at the hprt locus in Werner syndrome cells by multiplex PCR
• 熱中性子照射におけるDNA-PKcs阻害剤の生物学的効果
• ホウ素中性子捕捉療法後の末梢血リンパ球におけるマイクロヌクレウスの出現頻度の評価
• Mechanism of radiation-induced delayed mutagenesis
• Delayed Induction of DNA Damage and Activation of p53 in X-ray Surviving Cells
• Participation of ATM function in X-ray-induced delayed chromosomal instability
• Biological Action of Curcumin on Transformed Mouse Cells
• Biological Action of Curcumin on Transformed Mouse Cells
• Role of Ser15, Thr18, and Ser20 phosphorylation in p53 stabilization after X-irradiation
• X-rays-induced phosphorylation of H2AX in mitotic cells
• The role of telomerase activity in the radiation carcinogenesis processes of normal human cells
• Distinct Response of Irradiated Normal Human Fibroblasts and Their Bystander Cells to Heavy-Ion Radiation in Confluent Cultures
• Ceramide Induces Myogenic Differentiation and Apoptosis in Drosophila Schneider Cells
• Heavy-ion-induced bystander killing of human lung cancer cells : Role of gap junctional intercellular communication
• 8^ International Workshop on Microbeam Probes of Cellular Radiation Response
• Microbeams of Heavy Charged Particles
• An Alternative Mechanism for Radioprotection by Dimethyl Sulfoxide; Possible Facilitation of DNA Double-strand Break Repair
• Introduction of human gadd45 gene to human immortal cell lines using the inducible expression vector
• 211 Effect of RibCys on scavenging long-lived radicals and reducing gene mutation in mammalian cells by adding AFTER irradiation(Physics, chemistry and DNA damage, Abstracts of the 46th Annual Meeting of the Japan Radiation Research Society)
• Mechanisms of cell death by heat
• The number of Platinum Atoms Binding to DNA Molecules in SHOK Cells Transformed by Various Oncogenes Treated with ^mPt-cis-Diammine-dicliloroplatinum
• The effect of antisense fibronectin gene expression on human cells.
• Cellular response and p53 accumulation following heat shock in normal human cells
• The effect of adaptive response on radiation-induced genetic instability
• Radiation-induced genetic instability in mouse m5S cells
• Role of heat-shock protein 72 on expression of malignant phenotypes in cancer cells.
• Effect of low dose radiation on in vitro life span of human embryo cells
• Changes of malignant phenotyps in human canncer cells transfected with antisense-human hsp72 gene.

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