Wortmannin Radiosensitization and DNA DSB Repair

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概要

• 論文の詳細を見る
• 日本放射線影響学会の論文

著者

• UTSUMI HIROSHI

  Research Reactor Institute, Kyoto University

• UTSUMI Hiroshi

  Res. React. Inst. Kyoto Univ.

• Utsumi Hiroshi

  Research Reactor Institute Kyoto University

• Utsumi Hiroshi

  Health Res. Foundation

• HASHIMOTO Mitsumasa

  Res. React. Inst. Kyoto Univ.

• Hashimoto Mitsumasa

  Kyoto Univ.

• Utsumi Hiroshi

  Kyoto Univ.

• Takata Minoru

  Dep. Of Late Effects Studies Radiation Biology Center Kyoto Univ.

• Takeda Shunichi

  Department Of Radiation Genetics Faculty Of Medicine Yoshidakonoe-cho Sakyo-ku Kyoto University

• Takeda Shunichi

  Dept. Radiat. Gen. Kyoto Univ.

• Hashimoto Mitsumasa

  Research Reactor Institute Kyoto University

• Takata Minoru

  Immunology And Molecular Genetics Kawasaki Medical School

• Takata Minoru

  Dept. Of Cardiovascular Mol. Biol. Lederle Lab.

• Yamamoto Kazuo

  東北大学 生命科研究

• Rao Satish

  Res. Reactor Inst., Kyoto Univ.

• TAKATA Minoru

  Kawasaki Med. School

• YAMAMOTO Kenichi

  Cancer Res. Inst., Kanazawa Univ.

• TAKEDA Shunichi

  Radiat. Genet., Kyoto Univ.

• Yamamoto Kazuo

  大阪府立大学 生命環境科学部先端病態解析学

• Yamamoto K

  Department Of Molecular Pathology Cancer Research Institute Kanazawa University

• YAMAMOTO Kazuo

  Kanagawa Institute of Technology

• Utsumi H

  Research Reactor Institute Kyoto University

• Rao Satish

  Research Reactor Institute Kyoto University:department Of Radiobiology Kasturba Medical College

• Yamamoto K

  Kanagawa Institute Of Technology

• UTSUMI Hiroshi

  Res. React. Inst. , Kyoto Univ.

関連論文

• An Improved System for Selection of Forward Mutations in an Escherichia coli supF Gene Carried by Plasmids
• Analysis of the cell death after irradiation in the cells with defective DNA repair
• Analysis of the function of NBS1 in DNA double-strand break repair
• Disruption of the Schizosaccharomyces pombe homolog of MutY (SpMYH).
• Increased Base Change Mutations at G:C Pairs in Escherichiacoli Deficient in Endonuclease III and VIII
• Radiation sensitivity of RAD54^, KU70^ and RAD54^/KU70^ mutants of the chicken DT40 cell line.
• Screening of inhibitors specific for homologous recombination using D40 cell lines.
• Measurement of modified thymine derivatives with GC/MS
• Mutational Specificity Induced by hydrogen peroxides in hypocatalacemic mouse cell strain and in kat mutant Escherichia coli
• Changes of mutatinal spectrum of supF gene by delayed transfection after riboflavin photosensitization
• Is the Ku70 a Target of Wortmannin, Phosphatidylinositol 3-Kinase Inhibitor?
• Role of mitochondria on apoptosis induced by mAMSA
• Biological Effects of Intermediate Energy Neutrons
• X-ray Sensitive Cells, Cell Cycle Perturbations and Giant cells
• Mutational Specificity of SupF Gene Induced by Riboflavin-Photosensitization in Escherichia coli
• Formation of 8-hydroxyguanine and FapyGua in DNA by Riboflavin Mediated Photosensitization
• Mutational Specificity of the Ferrous Ion in a supF Gene of Endonuclease III/VIII Deficient Escherichia coli
• Analysis of DNA Damage and the Repair in D. radiodurans by Pulsed-Field Gel Flectrophoresis
• Cellular effect of thermal neutron capture treatment using ^B_1-para-boronophenylalanine: Lethal effect on melanoma cells with different degrees of X-ray sensitivity
• Analysis on DNA Double Strand Breakage and the Repair in D.radiodurans by Pulsed-Field Gel Electrophoresis
• The Mechanism of Increase in Drug Resistance in Polyploid Hamster Cells Induced by Cell Cycle-Perturbing Agents
• Genetic Instability Induced by Cell Cycle Arrest at M Phase in Chinese Hamster V79 Cells
• Genetic Instability Induced by Cell Cycle Arrest at S Phase in V79 Cells
• S-3-2 NHEJ pathway plays an important role in low dose-rate effects (LDRE)(Biological Effects of Low Dose and Low Dose-rate Irradiations, Abstracts of the 46th Annual Meeting of the Japan Radiation Research Society)
• Establishment of the Screening System for Spontaneous and Radiation-Induced Mutation Frequency in the Chicken DT40 Cells
• Relationship between cell killing and mutation induction by ionizing radiation in human lymphoblastoid cells
• Mutational Specificity Induced by Reactive Oxygen in Endonuclease III and VIII Deficient Escherichia coli.
• 3-Amino-1, 4-dimethyl-5H-pyrido[4,3-b]indole (Trp-P-1) Sensitizes Mammalian Cells to UV Radiation by Causing The S-Phase Arrest, Not by Inhibiting The Repair of DNA Damage as Observed in Escherichia coli
• Three-Dimensional Analysis of Nuclear Localization of Repair Sites of UV-lnduced DNA Damage by Laser Scanning Confocal Microscopy in Human Cells
• Current Topics in DNA Double-Strand Break Repair
• Homologous Recombination, DNA Double-Strand Repair, Required for the Repair of Sublethal Damage (Elkind Recovery).
• Characterization of RecA424 and RecA670 Proteins from Deinococcus radiodurans
• The Characterization of Deinococcus radiodurans RecA424 and RecA670 Proteins
• DNA Repair-promoting Protein from Deinococcus radiodurans
• Construction of Drug Resistance Gene Cassette for Specific Disruption of Deinococcus radiodurans Gene
• Cloning of the recA Gene from Deinococcus radiodurans and Its Expression in Escherichia coli
• Molecular analysis of a LexA homolog of radioresistant bacterium Deinococcus radiodurans
• Construction of Nbs1 knockout cell line using chicken DT40
• DNA-PK:the Major Target for Wortmannin-mediated Radiosensitization by the Inhibition of DSB Repair via NHEJ Pathway
• Wortmannin Radiosensitization and DNA DSB Repair
• Effects of Heavy-ion Radiosurgery on the Hemopoietic Function of the Silkworm Bombyx mori
• Radiosurgery applications of the local irradiation by heavy ion beams : Decrease of antibacterial activity ofhemolymph after local irradiation on the hemopoietic organs of larvae of silkworm, Bomyx mori
• Cell Irradiation System with a Single or Precise Numbers of Heavy Ions using a Collimated Heavy Ion Microbeamat TIARA, JAERI Takasaki
• Construction of Collimated Heavy Ion Microbeam System for Local Irradiation of Biological Targets
• Reverse genetic study of two major postreplicational repair pathways : homologous DNA recombination and translesion DNA synthesis
• dentification of Repair Enzymes Recognizing 7,8-Dihydro-8-oxo-guanine Opposite Guanine or Adenine in Escherichia coil
• Split Dose Recovery Studies using Homologous Recombination Deficient Gene Knockout Chicken B Lymphocyte Cells
• Heavy-ion microbeam system for cell irradiation at Kyoto University
• QUESTIONS IN CLASSICRADIATION BIOLOGY
• Radio- and drug-sensitivity of normal and acatalasemic mouse cell lines.
• Cooperation of tyrosine kinases p72^ and p53/56^ regulates calcium mobilization in chicken B cell oxidant stress signaling
• Syk and Lyn Are Involved in Radiation-Induced Signaling, but Inactivation of Syk or Lyn alone Is Not Sufficient to Prevent Radination-Induced Apoptosis
• Application of a Collimated Heavy Ion Microbeam System at TIARA for Local Irradiation of Biological Targets
• The Resistance Mechanism of Deinococcus radiodurans to Ultraviolet Light : UVDE, UvrA1, and UvrA2Pathways
• 143 The functional characterization of Nth homologue in hyperthermophilic archaeon Pyrococcus horikoshii OT3(Redox regulation, Abstracts of the 46th Annual Meeting of the Japan Radiation Research Society)
• Detection of DNA Damage in Individual Cells Induced by Heavy-ion Irradiation with an Non-denaturing Comet Assay
• Characterization of Spontaneous Mutation in the ΔsoxR and SoxS Overproducing Strains of Escherichia coli
• Detection of DNA damage in the individual cells induced by heavy ion microbeam irradiation with the cometassay.
• Irradiation of Collimated Heavy Ion Beams on Individual Cells
• Generation of 'OH and oxidative DNA lesions in aerobically grown E. coli lacking both SOD and Fur
• Implication of iron in spontaneous mutagenesis in E. coli mutants lacking reactive oxygen species (ROS) scavenging enzymes.
• Spectrum of Spontaneous Mutations in the Cyclic AMP Receptor Protein Gene on Chromosomal DNA of Escherichia coli
• Enzymatic Repair Mechanisms for Base Modifications Induced by Oxygen Radicals
• Biological Roles of Thymine Glycol
• First-Principles Study of C_6M_2 (M = B, Al, Mg, Li), C_7B and Related Compounds
• Electronic and Lattice Properties of MgB_2 and Related Phases under Various Compression Conditions
• Detection of Hypoxic Cells in Murine Tumors Using the Comet Assay: Comparison with a Conventional Radiobiological Assay
• Spectrum of Spontaneous Mutation of E. Ccli Crp Gene
• What is targets of fast repair of potentially lethal damage ?
• Asymmetric crossing over in the formation of deletions in the tonB-trp region of an Escherichia coli polA strain.
• Effects of the 5'- and 3'-Flanking bases on the Formation of G→T Transversion by 8-oxoG.
• Electronic and Lattice Properties of MgB_2 under a, b-axis Compression
• Electronic Structures of MgB2 under Uniaxial and Hydrostatic Compression

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