The Circulatory Disturbance of Spinal Cord Injury and Its Response to Local Cooling Therapy
スポンサーリンク
概要
- 論文の詳細を見る
Thirty adult dogs were subjected to immobilization of the spinal cord under nembutal anesthesia to produce spinal cord injury of two different degrees of severity by means of an impact of 500 G. cm or more and 300 G. cm or less respectively. In one group of animals an assessment was made of the resultant disturbance of spinal cord circulation at its acute stage while registering the serotonin content of the injured segment of the spinal cord as well as the evoked spinal cord potentials in response to peripheral nerve stimulation. The other group underwent local spinal cord cooling (1000 ml/hr.) for a comparison with the nontreated group of the ensuing changes in the circulatory disturbance of the spinal cord. As a result, it was found that the impact on the spinal cord, because of the anatomical constitution of the spinal arteries and veins as well as the specific features of spinal cord circulation, gave rise to rupture of microvessels in the central gray substance along with petechial hemorrhage, which in turn led to elevated serotonin level in the injured area, and that these two phenomena were responsible for the subsequent deterioration of spinal cord circulation with increased central necrosis. It was shown that the local cooling method is effective in ameliorating microcirculation and correcting the metabolic acidosis due to the impact and also in inhibiting the formation of serotonin which acts adversely in these respects.
- 社団法人日本脳神経外科学会の論文
著者
-
Goto Toshikazu
Department Of Neurological Surgery Nihon University School Of Medicine
-
Goto Toshikazu
Department Of Electrical Engineering Faculty Of Engineering Science Osaka University
-
Hayashi Nariyuki
Department of Emergency and Critical care Medicine, Nihon University School of Medicine
-
Nakamura Saburo
Department Of Neurological Surgery Nihon University School Of Medicine
-
TSUBOKAWA Takashi
Department of Neurological Surgery, Nihon University School of Medicine
-
TAGUMA Norikata
Department of Neurological Surgery, Nihon University School of Medicine
-
SUGAWARA Takehito
Department of Neurological Surgery, Nihon University School of Medicine
-
MORIYASU Nobuo
Department of Neurological Surgery, Nihon University School of Medicine
-
Hayashi Nariyuki
Department Of Neurological Surgery Nihon University School Of Medicine
-
Hayashi Nariyuki
Department Of Emergency And Critical Care Medicine Nihon University School Of Medicine
-
Hayashi Nariyuki
Department Of Neurological Surgery School Of Medicine Nihon University
-
Moriyasu Nobuo
Department Of Neurological Surgery Nihon University School Of Medicine
-
Moriyasu Nobuo
Department Of Neurological Surgery Faculty Of Medicine University Of Nihon
-
Tsubokawa Takashi
Department Of Neurological Surgery Nihon University School Of Medicine
-
Tsubokawa Takashi
Department Of Neurological Surgery School Of Medicine Nihon University
-
Tsubokawa Takashi
Department Of Neuroligical Surgery Nihon University School Of Medicine
-
Moriyasu Nobuo
Department Of Neurological Surgery School Of Medicine Nihon University
-
Taguma Norikata
Department Of Neurological Surgery Nihon University School Of Medicine
-
Sugawara Takehito
Department Of Neurological Surgery Nihon University School Of Medicine
-
Nakamura Saburo
Department Of Internal Medicine Tsuruga City Hospital
-
Sugawara Takekito
Department Of Neurological Surgery Nihon University School Of Medicine
-
Naakmura Saburo
Department Of Neurological Surgery School Of Medicine Nihon University
-
GOTO Toshikazu
Depart-ment of Internal Medicne Yamagata Prefectural Central Hospital
関連論文
- Implication of Endogenous Prostaglandin System in the Antihypertensive Effect of Captopril,SQ14225, in Low Renin Hypertension : IX Conference on the Pathogenesis of Hypertension
- THE ROLE OF RENAL PROSTAGLANDIN E AND KALLIKREIN IN PATHOGENESIS OF ESSENTIAL HYPERTENSION
- Randomized comparison of vasopressin and epinephnine in patients out-of-hospital cardiac arrest
- Resuscitative Value of B-Type Natriuretic Peptide in Comatose Survivors Treated With Hypothermia After Out-of-Hospital Cardiac Arrest due to Cardiac Causes
- EXERCISE STRESS THALLIUM-201 SPECT IN THE PATIENTS WITH ST-T CHANGE IN ECG AT REST OR DURING EXERCISE
- -0545-DIURNAL BLOOD PRESSURE RHYTHM IN SHIFT WORKERS
- 胃胆管瘻を伴ったムチン産生性胆管乳頭腫症
- The Circulatory Disturbance of Spinal Cord Injury and Its Response to Local Cooling Therapy
- Experimental Primary Fatal Head Injury Caused by Linear Acceleration-Biomechanics and Pathogenesis
- 5. The Appearance of Rhythmic Slow Wave in the Subthalamic Nucleus and Ventral Tegmental Area Related with Monoamine Contents
- S-8. The Treatment of Cervical Cord Injury : Effect and limitation of local cooling
- B-40. Alteration of Regional Cerebral Blood Flow in the Deep Cerebral Structure relating with Cerebral Tissue Monoamine Metabolisms in Experimental Increased Intracranial Pressure
- B-5. Experimental Studirs on the Adjuvant Therapy in Brain Tumor : Focusing on the Radio-Immune Therapy,as a Adjuvant Therapy for the Bain Tumor
- 47. Studies on water, electrolytes and adrenal function in cases of cerebral injury and cerebral injury and cerebral surgery.
- 152. A Study of the Conjunctival Vessels during Convulsion.
- S-2. The Functional Relationship between Centre Median Nucleus and Relay Nucleus for Relief of Intractable Pain
- B-54. The Hypoxemia and Hyperventilation caused by Severe Brain Injury
- S-4. Functions of the Pallido-Subthalamic Fiber
- 16. Lateral Pallidotomy for Relief of Hemibaooism
- Direct Patterning of Spin-on Glass by Focused Ion Beam Irradiation
- Active Neural Processes within the Brain Stem in Production of Coma : Araki's Coma-puncture Revisited
- Cortical Hyperactivity Following Thalamocortical Deafferentation in the Rat : The Role of N-Methyl-D-aspartate Receptor-Coupled Ion Channels
- Embolization of Intramedullary Spinal Arteriovenous Malformation Fed by the Anterior Spinal Artery with Monitoring of the Corticospinal Motor Evoked Potential : Case Report
- Effects of Thalamic Sensory Relay Nucleus Stimulation on Trigeminal Subnucleus Caudalis Neurons in the Cat : Abnormal Bursting Hyperactivity after Trigeminal Rhizotomy
- Effects of Thalamic Sensory Relay Nucleus Stimulation on Trigeminal Subnucleus Caudalis Neurons in the Cat : Nociceptive Activity in Response to Tooth Pulp Stimulation
- Pathogenetic Mechanism of Cerebral concussion due to Rotational Angular Acceleration Impact
- Coma induced by cholinergic activation of a Restricted Region in the Pontine Reticular Formation : -A Model of Reversible forms of Coma-
- Ruptured Aneurysm at the Origin of Duplication of the Middle Cerebral Artery : Case Report
- B-Type Natriuretic Peptide as a Marker of Resuscitation in Patients With Cardiac Arrest Outside the Hospital
- An Early and Complete Reperfusion Strategy for Acute Myocardial Infarction Using Fibrinolysis and Subsequent Transluminal Therapy : The FAST Trial
- S-B-8. Side Effect of Bilateral CEM-Thalamotomy with Special Reference to Transient Distrubance of consciousness
- S-B-7. The Relation between Localization of Lesion Site and the Effect of CEM-Thalamotomy with Special Reference to Analysis of the Autopsy Cases
- The vasoactive mediators in patients with shock and hypotension due to volume, pump and rate problems
- Far-field Responses of Acoustic Brain Stem Potentials in the Thalamus and the Subthalamic Area
- N-2 N-2. The Case who was only temporally controlled for Intractable Pain following Thalamotomy (PROCEEDINGS OF THE IVth ANNUAL MEETING OF THE JAPAN SOCIETY FOR RESEARCH IN STEREOENCEPHALOTOMY)
- 16 16. Bilateral CM Thalamotomy for Relief of Intractable Pain at One Stage : Its Effects and Side Effect (PROCEEDINGS OF THE IVth ANNUAL MEETING OF THE JAPAN SOCIETY FOR RESEARCH IN STEREOENCEPHALOTOMY)
- Studies on the Innervation of Pulmonary Circulation : PROCEEDINGS OF THE 25TH ANNUAL MEETING JAPANESE CIRCULATION SOCIETY (Part II)
- 81. Studies on Metabolism in Case of Brain Tumor and Brain Lesion : with Special Reference to its Influence to Liver Function.
- 57. Studies on the Genesis of Acute Pulmonary Edema after Brain Operation
- 127. Microelectrode Studies on the Intramedullary Courses of the Thoracic Vagal Nerve of a Cat.
- 126. Microelectrode Studies on Respiratory Potentials in the Bulb of a Cat.
- 109. Positive Contrast Cerebral Vintriculography Using Water-Soluble Media
- 128 128. Histological Study of the Brain Stem in Cases of Supratentorial Tumors
- 25. A report of a case of toxoplasmosis.
- B-32. Experimental Study of the Cerebrospinal Fluid Circulation under Obstruction of the Superior Sagittal Sinus
- D-22. An Autopsy Case of Cerebral Softening with Abnormal Vascular Network in the Cerebral Basal Region (Special Discussion:Occulsive Arterial Disorders of the Main Trnks of the Cerebral Arteries,Particularly Found in Japan)
- Distinct Time Courses of Secondary Brain Damage in the Hippocampus Following Brain Concussion and Contusion in Rats
- Experimental and Clinical Studies on Prognosis-Deteriorating Factors in the Acute Stage of Intraventricular Hemorrhage
- An Ultrastructural and Immunohistochemical Study of Central Neurocytoma
- Pituitary Adenoma Combined with Rathke's Cleft Cyst : Case Report
- Calcium Ions and Morphological Changes in the Arterial Wall after Subarachnoid Hemorrhage, with Special Reference to Human Subjects
- Appearance of Collagen Fibers in the Cerebral Vascular Wall Following Subarachnoid Hemorrhage
- 78. Responese Induced in the Midbrain and Thalamus of the Cat by Mecanical Stimulation of the Abdominal Viscera
- A-85. Experimental Study of Cerebral Arterial Occlusion under Normothermia : The Changes of Cerebral Blood Flow and Metabolism Following Occlusion
- S-2. Effect of Low Frequency Stimulation to the Nucleus Centrum Medianum and Its Vicinity,with Special Reference to Recruiting Response (Symposium:Human Depth Electrophysiology)
- 99 99. Studies on the Inhibitory and Facilitatory Mechanisms of Neurons in the Nucleus Tractus Solitarius of Cat
- Prognostic Value of Blood Glucose in Patients With Cardiogenic Shock
- DISTRIBUTION OF ACTIVATING NEURONS IN MEDULLA OBLONGATA BY STIMULATION OF THE VAGUS NERVE
- 39 Effect of Hypothermia on Evoked Potentials of the Lemniscal and Extralemniscal Systems
- 15 Inhibitory Effects of the Lower Medulla Stimulation of the Evoked Potentials in the Anterolateral Fasciculus of the Spinal Cord Subsequent to the Splanchnic Nerve Stimulation
- 5. Studies on the afferent pathway of the carotid sinus nerve.
- 43. An Experimental Study on Chemodynamic Circulation of Dogs at the Increased Intracranial Pressure
- The Significance of Right Ventricular Ischemia in Reflex Bradycardia in Humans
- Giant Cells in Tumors Associated with Tuberous Sclerosis : An Immunohistochemical and Electron Microscopic Study
- Fine structure of epithelioid cells in cerebral tuberculoma
- Pleomorphic xanthoastrocytoma: Ultrastructural study and origin of the tumor
- Cerebellar Malignant Glioma after Radiation Therapy for Suprasellar Germinoma : Case Report
- 102. Roentgenological Observation of the Regeneration in 103 Cases ofPostoperative Skull Defect (Proceedings of the XXVth Annual Meeting of the Japan Neurosurgical Society)
- Electron Microscopic Study of Ventricular Wall and Choroid Plexus in Experimentally-Induced Hydrocephalic Dogs
- B-15. Electron Microscopic Study of Choroid Plexus and Ventricular Wall in Experimentally Induced Hydrocephalic Dog
- B-46. Pathogenesis of traumatic Spinal hemorrhagic Necrosis The Role of Endogenious 5HT
- B-31. Hydrostatic and Ultrastructural Findings Indicating Arrestsr Hydrocephalus and Its Pathogenesis
- A-40. Cerebral Venous Circulation,Local Tissue Perfusion Pressire and Regional Cerebral Blood Flow in Experimental Increased Intracranial Pressure
- A-68. Immunologic Significance of Lymphoid Cells against Pineal Tumors in Man
- S-E-1 S-E-1. Studies on Pathophysiology and Treatment of the Change in Hemodynamics at the Acute Head Injury with Special Reference to the Cerebral Cell Function (Symposium E: Acute Head Injury)
- Regional Disparity in the Vascular Response to Subarachnoid Hemorrhage : Relationship between Alteration of the Concentration of Eicosanoids and Electron Microscopic Findings
- Prognosis of Chronic Subdural Hematoma using Noninvasive Skull Impedance Plethysmography
- OJ-153 Blood Glucose As A Marker Of Prognosis In Patients With Shock(Emergency Care (H) : OJ18)(Oral Presentation (Japanese))
- Clinical Significance of Changes in Blood Glucose and Neuroendocrine Hormones Due to the Stress Response in Patients with Severe Subarachnoid Hemorrhage
- Evaluation of p53 protein expression and proliferative potential base on the MIB-1 Positive index in astrocytic gliomas
- Intra-arterial ACNU Chemotherapy Employing 20% Mannitol Osmotic Blood-brain Barrier Disruption for Malignant Brain Tumors
- Changes in Glucagon Processing in Patients after Abdominal Surgery
- S-II-2. The Factors of Indication of Shunt Operation for Normal Pressure Hydrocephalus
- S-I-2 S-I-2. CM-Thalamotomy for Relief of Intractable Pain : Study for Perceptive mechanism of Intractable Pain (Symposium I: Pain)
- 3 Advanced Challenge in Resuscitation for Out-of-hospital Cardiac Arrest Due to Cardiac Causes(Symposium 6 (SY6) (IHD) : Treatment for CPA : Improving the Current Status?)(Special Program)
- S-B-7. The Relation between Localization of Lesion Site and the Effect of CEM-Thalamotomy with Special Reference to Analysis of the Autopsy Cases
- Two Types of Delayed Post-Traumatic Intracerebral Hematoma
- Improvement of pentobarbital-induced heart failure by MCI-154, a novel and potent cardiotonic agent, in the dog heart-lung preparation.
- 109. Positive Contrast Cerebral Vintriculography Using Water-Soluble Media
- Amelioration of heart failure by MDL 17043 and MDL 19205, novel positive inotropic drugs, in dog heart-lung preparations.