Effect of Chemoradiotherapy Using ACNU, Vincristine, and Nicardipine with High-dose Irradiation on Malignant Astrocytomas
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概要
- 論文の詳細を見る
Fifty-two patients with malignant astrocytoma were treated with cellular synchronization radiation therapy at the University of Tokyo Hospital between 1977 and 1989. Twenty-five patients (Group 1) received 1-(4-amino-2-methyl-5-pyrimidinyl) methyl-3-(2-chloroethyl)-3-nitrosourea hydrochloride (ACNU), vincristine, and 60Gy of irradiation, and 27 patients (Group 2) ACNU, vincristine, the Ca-channel blocker nicardipine, and 72Gy of irradiation. Median survival times for Groups 1 and 2 were 15 and 30 months, respectively. Although there was no significant difference, Group 2 achieved longer survival with 1-, 2-, and 3-year survival rates of 85.2, 65.8, and 46.9% compared to rates of 66.7, 40.0, and 26.7%, respectively, for Group 1.
- 日本脳神経外科学会の論文
- 1993-05-15
著者
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Takakura Kintomo
Department Of Neurosurgery Faculty Of Medicine University Of Tokyo
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Takakura Kintomo
Department Of Neurosurgery University Of Tokyo Hospital:m.d. Department Of Neurosurgery Neurological
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Nakamura Hirohiko
Department Of Neurosurgery Nakamura Memorial Hospital
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Nakamura Hirohiko
Department Of Neurosurgery University Of Tokyo Hospital:m.d. Department Of Neurosurgery Tokyo Metrop
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Shitara Nobuyuki
Department Of Neurosurgery University Of Tokyo Hospital:m.d. Department Of Neurosurgery Tokyo Metrop
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Shitara Nobuyuki
Department Of Neurosurgery Tokyo Metropolitan Komagome Hospital
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GENKA Shigeru
Department of Neurosurgery, University of Tokyo Hospital
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Takakura Kintomo
Department Of Neurosuegery National Cancer Center Hospotal
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Genka Shigeru
Department Of Neurosurgery University Of Tokyo Hospital:m.d. Department Of Neurosurgery Tokyo Metrop
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