A ROLE OF MATERNAL IMMUNE CHANGES IN THE MAINTENANCE OF CONCEPTUS AND IN THE TRIGGER OF LABOR

概要

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The changes in maternal cell-mediated immunity were studied throughout the course of pregnancy, delivery and puerperium. The study was conducted using two different indices: lymphocyte response per unit volume of peripheral blood to phytohemagglutinin (PHA) and the immuno-suppressive effect of serum on the response of normal lymphocyte to PHA stimulation. The results showed that decreased lymphocyted response and increased immuno-suppressive effect of serum contribute to the maintenance of the conceptus in utero and that opposite phenomena take place about 20 days before the onset of labor. It was concluded that a purposeful change in the maternal cell-mediated immunity plays a role in the maintenance of the fetus and its appendages and in triggering labor.
社団法人日本産科婦人科学会の論文
1977-09-01