Effects of astaxanthin on accommodation, critical flicker fusion, and pattern visual evoked potential in visual display terminal workers

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概要

• 論文の詳細を見る

• 赤色カロチノイドの一種であるアスタキサンチンのvisual display terminal(VDT)作業者の調節力,中心フリッカー値,パターン視覚誘発電位に及ぼす影響を調べた。VDT作業を行わない13人をコントロールとした(Group A)。26人のVDT作業者を2群に無作為に分けた。Group Bはアスタキサンチン一日5mg 4週間内服した13人で,Group Cはアスタキサンチンを含有しないカプセルを4週間内服した13人とした。外見上同じカプセルでの内服投与を行った。結果:Group AはGroup B及びGroup Cと比較して,調節力,中心フリッカー値は有意に高い値であったが,パターン視覚誘発電位検査結果は,Group B,Cと有意差はなかった。Group Bでは,アスタキサンチンの投与前後で有意な調節力の改善がみられた(p<0.01)。しかし,中心フリッカー値,パターン視覚誘発電位に変化はみられなかった。Group Cでは,投与前後で,調節力,中心フリッカー値,パターン視覚誘発電位に変化はみられなかった。考察:VDT作業者では,非作業者と比べ調節力,中心フリッカー値が低下していることは以前より報告されており,今回の我々の研究でも同様の結果であった。VDT作業者で,アスタキサンチン非内服群では,調節力は投与前後で変化がなかったが,アスタキサンチンの内服群で,有意に調節力が改善した。VDT作業者の調節力の改善には,アスタキサンチンの内服が有効と考えられた。

• 和漢医薬学会の論文

著者

• YAMADA Tetsuya

  Department of Occupational and Environmental Health, Nagoya University Graduate School of Medicine

• Nagaki Yasunori

  Department Of Ophthalmology Toyama Medical And Pharmaceutical University

• HAYASAKA Seiji

  Department of Ophthalmology, Toyama Medical and Pharmaceutical University

• HAYASAKA Yoriko

  Department of Ophthalmology, Toyama Medical and Pharmaceutical University

• Hotta Y

  Department Of Ophthalmology Juntendo University School Of Medicine

• Yamada T

  Plant Biotechnology Institute Ibaraki Agricultural Center

• Hayasaka Seiji

  Department Of Ophthalmology School Of Medicine University Of Toyama

• Hayasaka S

  Department Of Ophthalmology Shimane Medical University

• Hiratsuka Y

  Department Of Ophthalmology School Of Medicine University Of Toyama

• SANADA Mari

  Fuji Chemical Industry Co., LTD.

• UONOMI Takatoshi

  Fuji Chemical Industry Co., LTD.

• Hayasaka Yoriko

  Department Of Ophthalmology Toyama Medical And Pharmaceutical University

• Sanada Mari

  Fuji Chemical Industry Co. Ltd.

• Yamada Tetsuya

  Department Of Agricultural Chemistry Faculty Of Bioresources Mie University

• Hayasaka Seiji

  Department Of Ophthalmology Faculty Of Medicine Toyama Medical And Pharmaceutical University

• Uonomi Takatoshi

  Fuji Chemical Industry Co. Ltd.

• Nagaki Y

  Toyama Medical And Pharmaceutical Univ. Toyama Jpn

• Hayasaka Yuriko

  Department of Ophthalmology, Faculty of Medicine, Toyama Medical and Pharmaceutical University

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