EFFECTS OF STYRENE ON WHEEL-RUNNING AND AMBULATORY ACTIVITIES IN MICE
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概要
- 論文の詳細を見る
Effects of styrene on wheel-running and ambulatory activities were investigated in mice. Sixty male mice (ICR strain) were divided into 10 groups of six mice each, and they were exposed to styrene of about 930, 425, 60, 25 or 0 ppm (control group) for 4 hours a day, 5 days a week over 2 weeks. The wheel-running and ambulatory activity tests were conducted during 2 weeks of the styrene exposure, and 1 week before and after the exposure. The wheel-running activity decreased at the high concentrations (930 and 425 ppm), and the decreased activity did not recover to the control level after cessation of the exposure. In the ambulatory activity test, styrene exposure resulted in the decrease in the activity, though the change was not concentration-dependent. The present results suggest that the behavioral effect of styrene is clearly detectable by means of wheel-running and ambulatory activities in mice.
- 日本トキシコロジー学会の論文
- 1988-05-25
著者
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Teramoto K
Department Of Preventive Medicine And Environmental Health
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Teramoto Keiko
Department Of Preventive Medicine And Public Health Osaka City University Medical School
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Teramoto Keiko
Department Of Preventive Medicine And Environmental Health Osaka City University Medical School
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KURIBARA Hisashi
Division for Behavior Analysis, Behavior Research Institute, Gunma University School of Medicine
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WAKITANI Fumiko
Department of Preventive Medicine and Environmental Health
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TOJYO Fumio
Department of Preventive Medicine and Environmental Health
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TOKIMOTO Takayuki
The First Department of Physiology, Osaka City University Medical School
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Kuribara H
Wakanyaku Medical Inst. Ltd. Gunma Jpn
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Kuribara Hisashi
Division For Behavior Analysis Behavior Research Institute Gunma University School Of Medicine
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Tokimoto Takayuki
The First Department Of Physiology Osaka City University Medical School
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Horiguchi S
Department Of Preventive Medicine And Environmental Health
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TERAMOTO Keiko
Department of Preventive Medicine and Environmental Health
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