DISTRIBUTION, ELIMINATION AND RETENTION OF STYRENE IN RATS

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概要

• 論文の詳細を見る

• In rats exposed to styrene for 4 hours, the rate constant of elimination and biological half life of styrene were 0.11 and about 6 hours for adipose tissue, and 0.3 to 0.4 and about 2 hours for the other tissues, respectively. The relative ratio of apparent distribution of styrene decreased in the order adipose tissue > > liver > brain > kidney > blood ≑spleen > muscle. Almost the same results were obtained in the experiment by intraperitoneal injection of styrene. Repeated 4-hour exposures at about 700 ppm daily for five days caused the results similar to those in a single exposure. A trend of increase in concentration of styrene was observed in adipose tissue by 5 successive intraperitoneal injections every 6 hours at a dose of 350 mg/kg.

• 日本トキシコロジー学会の論文
• 1981-02-25

著者

• Teramoto Keiko

  Department Of Preventive Medicine And Public Health Osaka City University Medical School

• Teramoto Keiko

  Department Of Preventive Medicine And Environmental Health Osaka City University Medical School

• TERAMOTO Keiko

  Department of Preventive Medicine and Environmental Health

関連論文

• EFFECTS OF STYRENE ON WHEEL-RUNNING AND AMBULATORY ACTIVITIES IN MICE
• DISTRIBUTION, ELIMINATION AND RETENTION OF STYRENE IN RATS
• Effects of Styrene on Peripheral Nerve Conduction Velocities in Rats

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