ケトプロフェン注射剤と各種局所麻酔剤との配合変化

概要

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Compatibility tests on ketoprofen injection (Kp) with eight local anesthetics (LA) were performed in terms of pH, appearance, osmotic pressure against aline, and residual Kp after mixing. For admixing, following two methods were used. Group A : Kp is dissolved in distilled water for injection and then admixed with LA. Group B : Kp is directly dissolved in LA. The results are as follows : 1. Mixing with following drugs should be avoided : Group A : Percamin S, Carbocain (2%), Xylocaine E (1 and 2%), Marcain (0.25 and 0.5%), Citanest (1 and 2%). Group B : Bancain (2%), Percamin S, Carbocain (2%), Xylocaine E (1 and 2%), Xylocaine (3%), Marcain (0.5, 1 and 2%). 2. Mixing with following drugs should be made with caution. Group A : Bancain (2%), Calbocain (1%), Xylocaine (1,2 and 3%), Xylocaine E (0.5%). Group B : Xylocaine (1 and 2%), Xylocaine E (0.5%).
日本医療薬学会の論文
1986-08-20