PRELIMINARY OBSERVATION ON THE ABSENCE OF GLOBULE LEUCOCYTES IN MAST CELL-DEFICIENT W/W^V ANEMIC MICE AFTER TRICHINELLA SPIRALIS INFECTION

概要

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No proliferation of globule leucocytes was observed in congenitally mast cell-deficient (WB × C57BL/6)F_1-W/W^V anemic mice during the time course between 5 and 35 days postinfection with Trichinella spiralis. On the contrary, in the intestine of C57BL/6-bg^J/bg^J and C3H/He mice, which had sufficient number of mast cells, an increasing number of globule leucocytes was observed intraepithelially on day 10 postinfection, after which it reached respective peaks of cell-proliferation on day 14 postinfection. The worms in W/W^V mice were sustained for a longer period than those in bg^J/bg^J and C3H/He mice. These results suggest a certain positive correlation between the infiltration of globule leucocytes and the rapidity of T.spiralis expulsion from the intestine.
北海道大学の論文
1983-10-31