施灸皮膚局所の単核球浸潤に及ぼす艾成分の影響

概要

論文の詳細を見る
In order to clarify the increase of protective effects by means of moxibustion, we investigated the chemotactic effects of a moxa-stimulation and a chemical component of moxa (3,5-dicaffeoylquinic acid) against rat mononuclear cells. In vivo migration assay performed by intravenous injection of fluorescein-labeled mononuclear cells into long term-moxa-stimulated rats showed a significant infiltration of the cells beneath the moxa-stimulated point of the skin. In vitro chemotactic assay using methanol-extract from moxa and 3,5-dicaffeoylquinic acid clearly showed that mononuclear cells derived from moxa-stimulated animals were attracted by the tested materials more effective than those from non-stimulated animals. These data suggest that the active infiltration of the mononuclear cells observed in the moxa-stimulated skin may be induced by the permeation of the moxa tar,ineluding 3,5-dicaffeoylquinic acid and the related caffee tannin, after burning of moxa. Moreover, it is supposed that the permeated components of moxa directly effect to the skinattracted immunocytes and that may induce the activation of the local and systemic immune system.
関西鍼灸大学の論文
1999-09-30