糖尿病治療薬の活性酸素に対する作用

概要

論文の詳細を見る
Recently the relation between diabetes mellitus and oxygen free radicals has been discussed. We studied the effects of oriental drugs (Hachimi-jio-gan and Byako-ka-ninjin-to) for diabetes mellitus on 1,1-diphenyl-2-picrylhydrazyl (DPPH) as a stable radical and on superoxide anion and hydroxyl radical as oxygen free radicals. Hachimi-jio-gan quenched DPPH, inhibited generation of superoxide anion, and showed inhibition of hydroxyl radical spin adduct. Byako-ka-ninjin-to showed inhibition of hydroxyl radical spin adduct only. These results suggested that oriental drugs for diabetes mellitus were able to protect against active oxygen species associated with the disease.
関西鍼灸大学の論文
1992-04-01