麻酔前投薬および導入に用いたミダゾラムの有用性

概要

論文の詳細を見る
The usefulness of midazolam combined with premedication and anesthetic induction in general anesthesia for dental treatment of intellectual disabilities was investigated in 19 patients. There were no significant defferences in sedative and hypnotic effects of premedication with O.1mg/kg of midazolam i. m. and 0.03mg/kg of flunitrazepam p. o.. The effect of anesthetic induction was compared for 0.2mg/kg of midazolam i. v. combined with nitrous oxide-oxygen-sevoflurane and nitrous oxide-oxygen-sevoflurane alone. Similar changes in blood pressure and heart rate at the perioperative stage were observed in either group. There were no significant defferences in the dose of sevoflurane and recovery times in either group. Although, all cases of the midazolam group had recovered completely 2 hours after arrival in the recovery room. From the results, midazolam was considered useful for premedication in general anesthesia for dental treatment of intellectually challenged outpatients.
北海道医療大学の論文
1997-06-30