歯科における精神鎮静法の研究 : 第1報ジアゼパム静脈内鎮静法の追加投与方法

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Intravenous sedation with monitored conscious sedation care was applied to cases of dental and minor oral surgical procedures under local anesthesia. Additional administration (time of injection and volume) of diazepam by intraveous injection was made to maintain conscious and optimum sedation during operation, from the post-investigative stage for clinical cases for satisfactory sedation during operation. Subjects for the statistical study provide dental treatment or operation consent to the application of diazepam intravenous sedation, and comprised 25 cases of ASA ps class I or II patients. Diazepam in intrvenous injection by titration, at the first injection established a standard of 0.2〜0.3mg/kg, and for intravenous injection taking at least one minute 5mg. The resulting first injection of diazepam was 0.226±0.051 (mean ± SD) mg/kg. The main reasons for additioal diazepam administration were, 0.051 (mean ± SD) mg/kg. The main reasons for additional diazepam administration were, increases in state anxiety, pain and stressors of the operation, movement and speaking clearly. Diazepam was mainly injected before of after the local anesthesia injection. It is neccessary to provide a first additional administration of 0.081±0.032mg/kg diazepam, 35.5±14.0minutes after the first injection. The second additional administration was 0.085±0.067mg/kg, 60.0±18.1minutes after the first injection. Operatio durations for fourteen cases with a first administration was 61.2±24.0minutes. Seven cases which needed a second additional adnimistration had operation times of 79.6±19.5minutes. The results showed that the additional injection of two fifths of the first intravenous injection resulted in an extension of sedation for sixty minutes. Taking account of time for sterilization and for the local anesthesia to take effect, diazepam appears suitable for 45 minute operations.
北海道医療大学の論文
1999-06-30

歯科における精神鎮静法の研究 : 第1報ジアゼパム静脈内鎮静法の追加投与方法

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