ヒト乳歯歯根吸収過程の組織細胞学・組織細胞化学的研究

概要

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Using extracted human deciduous teeth undergoing physiological root resorption, we studied the mechanisms of predentin resorption, deposition of cementum-like tissue in the resorption lacunae, and regulation of odontoclastic activity by light and confocal laser scanning microscopy, and scanning and transmission electron microscopy. Odontoclasts had ultrastructural and cytochemical characteristics as osteoclasts. These odontoclasts formed resorption lacunae on the nonmineralized predentin layer. The odontoclastic processes demonstrating tartrate-resistant acid phosphatase activity invaded the dentinal tubules deeply. These cell processes may play a role in resorption of predentin and dentin. Some mononuclear fibroblastic cells occupiyed the resorption lacunae and showing alkaline phosphatase activity, formed cementum-like tissue in the lacunae. Mononuclear fibroblastic cells surrounding odontoclasts may regulate odontoclastic resorptive activity. These results suggest functional differences between odontoclasts and osteoclasts.
北海道医療大学の論文
1997-06-30