Partial Purification and Demonstration of Anti-tumor Activity of High Molecular Weight DNA-binding Protein (HMDBP) in Ascitic Fluid of Mice with Meth-A Ascites Fibrosarcoma
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概要
- 論文の詳細を見る
この論文は国立情報学研究所の学術雑誌公開支援事業により電子化されました。A high molecular weight DNA-binding protein (HMDBP), from the ascitic fluid of mice with Meth-A ascites, was partially purified with isoelectric focusing column chromatography. The HMDBP was shown to be acidic in isoelectrophoresis. It did not cross-react with IgA, IgM and IgG. The major HMDBP was determined, by sodium dodecylsulfate gel electrophoresis, to be about 160,000 daltons. In tumor cell cultures, HMDBP suppressed the growth of tumor cells. Therefore, this high molecular weight DNA-binding β-globulin may play a role in controlling tumor growth.
- 京都大学の論文
- 1983-07-30
著者
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HASHIMOTO Kenji
Department of Oral and Maxillofacial Surgery, Hamamatsu University School of Medicine
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HIGUCHI Keiichi
Department of Aging Biology, Institute on Aging and Adaptation, Shinshu University Graduate School o
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YASUHIRA KIMIO
Department of Pathology, Chest Disease Research Institute, Kyoto University
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Yasuhira Kimio
Department Of Pathology Chest Disease Research Institute Kyoto University
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Higuchi Keiichi
Department Of Pathology Chest Disease Research Institute Kyoto University
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Higuchi Keiichi
Department Of Aging Angiology Research Center For Aging And Adaptation Shinshu University
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Hashimoto Kenji
Department Of Biotechnology And Life Science Tokyo University Of Agriculture And Technology
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Hashimoto Kenji
Department Of Pathology Chest Disease Research Institute Kyoto University
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Hashimoto Kenji
Department Of Anatomy Nara Medical University
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