<基礎的研究発生病理>潜水型T型水迷路試験におけるSHR, SHRSPの学習行動

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Severa water tasks are widely used as behavioral and learning ability tests in teratology studies. These tasks can examine many animals in a relatively short time in a simple apparatus, without hard stress such as food deprivation in the growing period. The purpose of this study is to use the under water T maze apparatus to investigate the learning ability of SHR, SHRSP and WKY mature male rats (14-18 weeks of age) bred in our laboratory. The swimming time and errors (selecting and backing errors) were recorded. There were no significant differences in the swimming time among the three strains from day 1 to day 3 trials. In the goal reversed trials on day 4,the swimming time of SHRSP was significantly longer than that of WKY. After several trials from day 1 to day 3,SHR and SHRSP showed a decrease in mean error counts. Especially SHR had significantly fewer error counts on day 3 trials than WKY. On day 4,when the goal was reversed, error counts were similar among the three strains. They showed a rate of errorless performance similar to day 1 trials. However, for day 2 and day 3 trials, the rates of errorless performance of SHR and SHRSP were significantly higher than those of WKY. On day 4,for the goal reversed trial, there were no significant differences among the three strains. It is concluded that SHR and SHRSP show better learning ability, as indicated by their higher level of errorless performance in this test system.
近畿大学の論文
1988-12-30

<基礎的研究発生病理>潜水型T型水迷路試験におけるSHR, SHRSPの学習行動

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