高血圧自然発症ラット(SHR)および脳卒中易発症性SHR(SHRSP)の発生学的研究(I 発生病理)(A 基礎的研究)

概要

論文の詳細を見る
Reproductions as well as pre- and postnatal developments of WKY, SHR and SHRSP rats were compared. No differences were observed among the three strains on pregnancy rate, preimplantation loss and incidence of the intrauterine death. Perinatal mortality and survival rate on day 4 were comparable among the three strains. However, the weaning rate of SHRSP was slightly lower as compared to the other two strains. The fetal body weight of SHR and SHRSP on day 21 of gestation was significantly lower than that of WKY. No significant difference of the body weight at one day after birth was noted between SHR and WKY. It may be due to the catching up of intrauterine growth in the final day of gestation in SHR, because the gestation period is longer by one day in this strain as compared to WKY. The body weight of SHRSP at one day after birth was significantly lower than that of SHR or WKY. The body weight of SHR became inferior to that of WKY after 11 weeks of age. No case of external malformations was observed at term in any of these three groups.
近畿大学の論文
1981-09-25