Molecular Mechanisms Involved in Adaptive Responses to Radiation, UV light, and Heat
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概要
- 論文の詳細を見る
Viable organisms recognize and respond to environmental changes or stresses. When these environmental changes and their responses by organisms are extreme, they can limit viability. However, organisms can adapt to these different stresses by utilizing different possible responses via signal transduction pathways when the stress is not lethal. In particular, prior mild stresses can provide some aid to prepare organisms for subsequent more severe stresses. These adjustments or adaptations for future stresses have been called adaptive responses. These responses are present in bacteria, plants and animals. The following review covers recent research which can help describe or postulate possible mechanisms which may be active in producing adaptive responses to radiation, ultraviolet light, and heat.
- 2009-09-16
著者
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OHNISHI Takeo
Department of Biology, School of Medicine, Nara Medical University
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Ohnishi Takeo
Department Of Biology Nara Medical University
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Takahashi Akihisa
Department Of Biology Nara Medical University
関連論文
- The Foci of DNA Double Strand Break-recognition Proteins Localize with γH2AX after Heat Treatment
- ATM is the Predominant Kinase Involved in the Phosphorylation of Histone H2AX after Heating
- DNA Damage Recognition Proteins Localize along Heavy Ion Induced Tracks in the Cell Nucleus
- コンピュータによるイメージ加工と温熱誘導γH2AXフォーカスの解析
- Molecular Mechanisms Involved in Adaptive Responses to Radiation, UV light, and Heat
- Impact of the p53 Status of the Tumor Cells on the Effect of Reactor Neutron Beam Irradiation, with Emphasis on the Response of Intratumor Quiescent Cells
- High LET Heavy Ion Radiation Induces p53-Independent Apoptosis
- High LET radiation enhances apoptosis in mutated p53 cancer cells through Caspase-9 activation
- The Biology of Heat-induced DNA Double-Strand Breaks
- Time Course and Spacial Distribution of UV Effects on Human Skin in Organ Culture
- Development of thermotolerance requires interaction between polymerase-β and heat shock proteins
- The First Life Science Experiments in ISS : Reports of "Rad Gene"-Space Radiation Effects on Human Cultured Cells-
- Recent Advances in the Biology of Heavy-Ion Cancer Therapy
- ATM is the Predominant Kinase Involved in the Phosphorylation of Histone H2AX after Heating
- Usefulness of Hexamethylenetetramine as an Adjuvant to Radiation and Cisplatin in the Treatment of Solid Tumors : its Independency of p53 Status
- Inhibition in a microgravity environment of the recovery of Escherichia coli cells damaged by heavy ion beams during the NASDA ISS Phase I Program of NASA Shuttle/Mir Mission No. 6
- Effects of p53 Status and Wortmannin Treatment on Potentially Lethal Damage Repair, with Emphasis on the Response of Intratumor Quiescent Cells
- Usefulness of combined treatment with mild temperature hyperthermia and/or tirapazamine in the treatment of solid tumors : its independence of p53 status
- コンピュータによるイメージ加工と温熱誘導γH2AXフォーカスの解析
- p53-Dependent Signal Transduction Induced by Stress
- Cell growth and morphology of Dictyostelium discoideum in space environment
- Cell growth and morphology of Dictyostelium discoideum in space environment
- Restraint Plus Water-immersion Stress (RWIS)-induced Stomach Ulcers in Mice are Depressed by a Conditioning Heat Treatment
- Expression of p53-Regulated Genes in Cultured Mammalian Cells After Exposure to A Space Environment
- Light-Induced Anthocyanin Reduces the Extent of Damage to DNA in UV-Irradiated Centaurea cyanus Cells in Culture
- The effect of clinorotation on vestibular compensation in upside-down swimming catfish
- Vanguards of Paradigm Shift in Radiation Biology: Radiation-Induced Adaptive and Bystander Responses
- Radiation-Induced Adaptive Responses and Bystander Effects
- DNA Damage Formation and p53 Accumulation in Mammalian Cells Exposed to the Space Environment
- Usefulness of Hexamethylenetetramine as an Adjuvant to Radiation and Cisplatin in the Treatment of Solid Tumors: its Independency of p53 Status
- p53遺伝子背景に関係ないHSPを介したあらかじめの温熱処理による温熱抵抗性および放射線抵抗性の獲得
- The Significance of the Study about the Biological Effects of Solar Ultraviolet Radiation using the Exposed Facility on the International Space Station
- DNA-Damaging Agents Induce the 72-kD Heat Shock Protein in SV40 Transformed Normal Human Fibroblasts
- Hypergravity Modifies the Signal Transduction of Ionizing Radiation through p53
- The Biological Effects of Space Radiation during Long Stays in Space
- High transmittance of X-rays in the utricular otolith of upside-down swimming catfish, Synodontis nigriventris
- Mutation Frequency of Plasmid DNA and Escherichia coli Following Long-term Space Flight on Mir
- The Role of p53 Molecule in Radiation and Hyperthermic Therapies
- Analysis of Apoptosis-related Gene Expression after X-ray Irradiation in Human Tongue Squamous Cell Carcinoma Cells Harboring Wild-type or Mutated p53 Gene
- Detection of DNA Damage Induced by Space Radiation in Mir and Space Shuttle
- Mutation frequency of Dictyostelium discoideum sporcs exposed to the spase environment
- Nitric Oxide Radical-induced Radioadaptation and Radiosensitization Are G2/M Phase-dependent
- DNA ligase IV is a potential molecular target in ACNU sensitivity
- A Special Section : The Radioadaptive Response
- Pre-irradiation at a Low Dose-rate Blunted p53 Response
- Chemotherapy Combined with Hyperthermia Improves the Prognosis for Non-small-cell Lung Cancer
- 細胞の生死にかかわる温熱誘導シグナル伝達経路
- Preface : Space Radiation Biology
- Postural control under clinorotation in upside-down catfish, Synodontis nigriventris
- Relationship between frequency of upside-down posture and space size around upside-down catfish, Synodontis nigriventris
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- Nitric Oxide Radical-induced Radioadaptation and Radiosensitization Are G_2/M Phase-dependent
- Phospho-Nbs1 and Mre11 proteins which recognize DSBs co-localize with γH2AX in the nucleus after heat treatment
- Studies about Space Radiation Promote New Fields in Radiation Biology
- Biological Effects of Space Radiation
- 抗トリパノゾ-マ薬品,Ro7-1051,の大腸菌における突然変異原性〔英文〕