γ-Glutamyl Transferase and Metabolic Risk Factors for Cardiovascular Disease
スポンサーリンク
概要
- 論文の詳細を見る
Objective To elucidate the mechanism of the reported association between serum γ-glutamyl transferase (GGT) activity and cardiovascular mortality.Methods Cross-sectional analysis of the relationship between serum GGT activity and the risk factors for cardiovascular disease was performed.Patients and materials Middle-aged Japanese male personnel of the Self-Defense Forces who underwent retirement check-up.Results Serum GGT activity was associated with total cholesterol, triglyceride, fasting plasma glucose, total homocysteine and systolic blood pressure. The association remained in the analysis adjusted for possible confounders including cigarette smoking, ethanol consumption and body mass index.Conclusion The observed association between serum GGT and cardiovascular risk factors may partly explain the reported relationship between serum GGT activity and cardiovascular disease. Serum GGT activity may be regarded as a marker of cardiovascular risk factors or oxidative stress rather than a mere indicator of excessive ethanol consumption or obesity.
- 社団法人 日本内科学会の論文
- 2005-06-01
著者
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SUZUKI Takashi
Department of Biochemistry, University of Shizuoka, School of Pharmaceutical Sciences, Core Research
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Ito Teizo
Department Of Internal Medicine Self Defense Forces Central Hospital
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Ito Teizo
Department Of Internal Medicine Japan Self Defense Forces Central Hospital
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Yasuda Hiroko
Department Of Internal Medicine Self Defense Forces Central Hospital
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Yasuda Hiroko
Department Of Applied Chemistry Graduate School Of Engineering Tohoku University
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Suzuki Takashi
Department Of Biochemistry University Of Shizuoka School Of Pharmaceutical Sciences:core Research Fo
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Sakuta Hiroki
Electron Tube Amp Devices Div. Hitachi Ltd.
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Sakuta Hidenari
Department Of Internal Medicine Self-defense Forces Central Hospital
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Suzuki Takashi
Department Of Research And Laboratory Self Defense Forces Central Hospital
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Suzuki Takashi
Department Of Anesthesia Showa University Northern Yokohama Hospital
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Suzuki Takashi
Department Of Anatomic Pathology Tohoku University School Of Medicine
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Yasuda Hiroko
Department of Internal Medicine, Self-Defense Forces Central Hospital
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