Synthetic Studies of Archaeal Macrocyclic Tetraether Lipids: Practical Synthesis of 72-Membered Tetraether Model Compounds

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概要

• 論文の詳細を見る
• Chemical Society of Japanの論文
• 1997-10-15

著者

• ARAKAWA Kenji

  Department of Chemistry, Box 351700, University of Washington

• Eguchi Tadashi

  Department Of Chemistry And Materials Science Tokyo Institute Of Technology

• Kakinuma Katsumi

  Tokyo Institute of Technology, Department of Chemistry

• Kakinuma K

  Tokyo Inst. Technol. Tokyo

• Kakinuma Katsumi

  Department Of Chemistry And Materials Science Tokyo Institute Of Technology

• KANO Hiroki

  Department of Chemistry, Tokyo Institute of Technology

• Arakawa K

  Univ. Washington Wa Usa

• Arakawa Kenji

  Department Of Chemistry Box 351700 University Of Washington

• Eguchi Tadashi

  Department Of Chemistry & Materials Science Tokyo Institute Of Technology

• Kano H

  Univ. Tokyo Tokyo

• Kakinuma Katsumi

  Department of Chemistry & Materials Science, and Department of Chemistry, Tokyo Institute of Technology

• Kano Hiroki

  Department of Chemistry and Materials Engineering, Faculty of Chemistry, Materials and Bioengineering, Kansai University

関連論文

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• Structure of NG-061, a Novel Potentiator of Nerve Growth Factor (NGF) Isolated from Penicillium minioluteum F-4627
• A Novel Fungal Metabolite NG-061 Enhances and Mimics Neurotrophic Effect of Nerve Growth Factor (NGF) on Neurite Outgrowth in PC12 Cells
• Biosynthesis of the Cyclitol Moiety of Pyralomicin 1a in Nonomuraea spiralis MI178-34F18
• Cloning of the Pactamycin Biosynthetic Gene Cluster and Characterization of a Crucial Glycosyltransferase Prior to a Unique Cyclopentane Ring Formation
• P-188 Functional Analysis of Unique Enzymes in the Biosynthesis of Aminoglycoside Antibiotics
• Biosynthesis of 2-Deoxystreptamine-containing Antibiotics in Streptoalloteichus hindustanus JCM 3268 : Characterization of 2-Deoxy-scyllo-inosose Synthase
• Biosynthesis of 2-Deoxystreptamine by Three Crucial Enzymes in Streptomyces fradiae NBRC 12773
• Extended Sequence and Functional Analysis of the Butirosin Biosynthetic Gene Cluster in Bacillus circulans SANK 72073
• Reaction Stereochemistry of 2-Deoxy-scyllo-inosose Synthase, the Key Enzyme in the Biosynthesis of 2-Deoxystreptamine
• First Identification of Streptomyces Genes Involved in the Biosynthesis of 2-Deoxystreptamine-containing Aminoglycoside Antibiotics : Genetic and Evolutionary Analysis of L-Glutamine : 2-deoxy-scyllo-inosose Aminotransferase Genes
• Identification of L-Glutamine : 2-Deoxy-scyllo-inosose Aminotransferase Required for the Biosynthesis of Butirosin in Bacillus circulans
• Novel Substrate Specificity of Designer 3-Isopropylmalate Dehydrogenase Derived from Thermus thermophilus HB8(Biochemistry & Molecular Biology)
• Butirosin-biosynthetic Gene Cluster from Bacillus circulans
• Significance of the 20-kDa Subunit of Heterodimeric 2-Deoxy-scyllo-inosose Synthase for the Biosynthesis of Butirosin Antibiotics in Bacillus circulans(Microbiology & Fermentation Technology)
• Molecular Cloning of the Gene for the Key Carbocycle-forming Enzyme in the Biosynthesis of 2-Deoxystreptamine-containing Aminocyclitol Antibiotics and Its Comparison with Dehydroquinate Synthase
• Purification and Characterization of 2-Deoxy-scyllo-inosose Synthase Derived from Bacillus circulans. A Crucial Carbocyclization Enzyme in the Biosynthesis of 2-Deoxystreptamine-containing Aminoglycoside Antibiotics
• Enantioselective Synthesis of (2R,3S)-3-Alkylmalic Acids, Competent Substrates for 3-Isopropylmalate Dehydrogenase
• Solvent-dependent Stereochemical Anomaly in the Nucleophilic Addition of Ester-derived Enolate to Bicyclo[3,3,0]octan-2-one System of Diacetone Glucos-3-ulose
• Isolation of Enterocin SE-K4-Encoding Plasmid and a High Enterocin SE-K4 Producing Strain of Enterococcus faecalis K-4
• Isolation and Characterization of Enterocin SE-K4 Produced by Thermophilic Enterococci, Enterococcus Faecalis K-4
• Characterization of a Phage Resistance Plasmid, pLKS, of Silage-Making Lactobacillus plantarum NGRI0101
• Ocular dominancy in conjugate eye movements at reading distance
• A new method for enzymatic preparation of isopentenyladenine-type and trans-zeatin-type cytokinins with radioisotope-labeling
• Versatile Synthon for Chirally β-Deuterated L-Amino Acids and Synthesis of (3R)- and (3S)-[3-^2H_1]-L-Serine
• Involvement of Glutamate Mutase in the Biosynthesis of the Unique Starter Unit of the Macrolactam Polyketide Antibiotic Vicenistatin
• Overproduction and Substrate Specificity of 3-Isopropylmalate Dehydrogenase from Thiobacillus ferrooxidans
• Biosynthesis of (2R)-4-Amino-2-hydroxybutyric Acid, Unique and Biologically Significant Substituent in Butirosins
• 3-Isopropylidenemalic Acid:A Mechanism-based Inhibitor of 3-Isopropylmalate Dehydrogenase
• Coenzyme Activity of NAD Analogs for 3-Isopropylmalate Dehydrogenase from Thermus thermophilus HB8
• Synthesis of 2-O-Methyl Ether and 1-Carboxamide Derivatives of (2R,3S)-3-Isopropylmalic Acid and Their Interaction with Thermophilic 3-Isopropylmalate Dehydrogenase
• Synthesis of NG-061 and Its Analogs, and Their Biological Evaluation as an Enhancer of Nerve Growth Factor
• Isolation and Characterization of a New Pyrano[4', 3': 6, 7]naphtho[1, 2-b]xanthene Antibiotic FD-594
• Optical Isolator for Orthogonally Polarized Two-Frequency Laser
• Significance of the 71-Membered Macrocyclic Structure Found in Archaeal Membrane Lipids : Model Studies of the Macrocyclic Tetraether Diphospholipids by Calorimetric, ^PNMR, and Electron Microscopic Analyses
• Regulation of Lankamycin Biosynthesis in Streptomyces rochei by Two SARP Genes, srrY and srrZ
• Substrate Specificity of 2-Deoxy-scyllo-inosose Synthase, the Starter Enzyme for 2-Deoxystreptamine Biosynthesis, toward Deoxyglucose-6-phosphates and Proposed Mechanism
• Kinetic Isotope Effect and Reaction Mechanism of 2-Deoxy-scyllo-inosose Synthase Derived from Butirosin-producing Bacillus circulans
• Biosynthesis of Archaeal Membrane Lipids : Digeranylgeranylglycerophospholipid Reductase of the Thermoacidophilic Archaeon Thermoplasma acidophilum
• pSLA2-M of Streptomyces rochei Is a Composite Linear Plasmid Characterized by Self-Defense Genes and Homology with pSLA2-L
• Extensive Mutational Analysis of Modular-Iterative Mixed Polyketide Biosynthesis of Lankacidin in Streptomyces rochei
• Analysis of Modular-iterative Mixed Biosynthesis of Lankacidin by Heterologous Expression and Gene Fusion
• Roles of a 20kDa Protein Associated with a Carbocycle-Forming Enzyme Involved in Aminoglycoside Biosynthesis in Primary and Secondary Metabolism
• Production and Structural Analysis of PP-V, a Homologue of Monascorubramine, Produced by a New Isolate of Penicillium sp.
• Structure and Biosynthesis of FD-594; a New Antitumor Antibiotic
• PC83 SARKOMYCIN ANALOGUES AS HIGHLY ACTIVE ANTIMUTAGENS AGAINST UV-INDUCED MUTATION IN Escherichia coli
• Possible Interaction of Thiol Groups of Proteins with Antimutagens Containing a Conjugated Carbonyl Structure(Organic Chemistry)
• Characterization of the Biosynthetic Gene Clusters Located on the Streptomyces Linear Plasmid
• Gene disruption analysis of two glycosylation steps in lankamycin biosynthesis in Streptomyces rochei
• Structure Revision of FD-891, a 16-Membered Macrolide Antibiotic
• P-51 Genome-Inspired Search for New Polyketide Antibiotic Halstoctacosanolides from Streptomyces halstedii HC34
• The Complete Biosynthetic Gene Cluster of the 28-Membered Polyketide Macrolactones, Halstoctacosanolides, from Streptomyces halstedii HC34
• Enantioselective and Convergent Synthesis of the 20-Membered Lactam Aglycon of Vicenistatin Antitumor Antibiotic
• Functional Analysis of Type 1 Isopentenyl Diphosphate Isomerase from Halobacterium sp. NRC-1
• MYOSIN ISOFORMS AND THEIR LOCALIZATION IN CYTOSOL AND MEMBRANE FRACTIONS OF PERITONEAL NEUTROPHILS FROM GUINEA PIG.(Biochemistry)(Proceedings of the Sixty-Second Annual Meeting of the Zoological Society of Japan)
• Electrophilic Reaction on Plinol C and Syntheses of Functionalized 2-Oxabicyclo[2,2,1]heptane Derivatives(Organic Chemistry)
• Highly Thermostable Liposome from 72-Membered Macrocyclic Tetraether Lipid: Importance of 72-Membered Lipid for Archaea to Thrive under Hyperthermal Environments
• 36-Membered Macrocyclic Diether Lipid is Advantageous for Archaea to Thrive under the Extreme Thermal Environments
• Specific Deuterium Labeling of Archaeal 36-Membered Macrocyclic Diether Lipid
• Tightly Packed Membranes Composed of 36-Membered Macrocyclic Diether Phosholipid Found in Archaea Growing under Deep-sea Hydrothermal Vents
• Structural Diversity of the Membrane Core Lipids of Extreme Halophiles
• Synthetic Studies of Archaeal Macrocyclic Tetraether Lipids: Practical Synthesis of 72-Membered Tetraether Model Compounds
• Short Synthesis of (±)-Chokol G, the Simplest Congenor of the Chokol Group of Fungitoxic Sesquiterpenoids(Organic Chemistry)
• Confirmation of the Absolute Stereo-chemistry of sn-2,3-Di-O-phytanyl Glycerol, the Unit Lipid of the Cell Membrane of Halophilic Archaebacteria Halobacterium halobium(Organic Chemistry)
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• pSLA2-M of Streptomyces rochei Is a Composite Linear Plasmid Characterized by Self-Defense Genes and Homology with pSLA2-L
• Real-Time Spectroscopy of the Excited-State Excitons in Porphyrin J-Aggregates
• Isolation of Borrelidin as a Phytotoxic Compound from a Potato Pathogenic Streptomyces Strain
• Structure of Thermus thermophilus homoisocitrate dehydrogenase in complex with a designed inhibitor
• The cytotoxic macrolide FD-891 induces caspase-8-dependent mitochondrial release of cytochrome c and subsequent apoptosis in human leukemia Jurkat cells
• Cloning of the biosynthetic gene cluster for naphthoxanthene antibiotic FD-594 from Streptomyces sp. TA-0256
• Biosynthetic genes for aminoglycoside antibiotics
• Indomethacin Induction of Metamorphosis from the Asexual Stage to Sexual Stage in the Moon Jellyfish, Aurelia aurita
• Indomethacin Induction of Metamorphosis from the Asexual Stage to Sexual Stage in the Moon Jellyfish, Aurelia aurita
• Enzymatic preparation of neomycin C from ribostamycin
• Enzymatic activity of a glycosyltransferase KanM2 encoded in the kanamycin biosynthetic gene cluster
• Differences in the Roles of a Glutamine Amidotransferase Subunit of Pyridoxal 5'-Phosphate Synthase between Bacillus circulans and Bacillus subtilis
• Characterization of Polyphosphate Glucokinase SCO5059 from Streptomyces coelicolor A3(2)
• Differences in the Roles of a Glutamine Amidotransferase Subunit of Pyridoxal 5'-Phosphate Synthase between Bacillus circulans and Bacillus subtilis

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