Relationship between Changes of Bone Mineral Content and Twelve-Minute Walking Distance in Men with Chronic Obstructive Pulmonary Disease : A Longitudinal Study
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概要
- 論文の詳細を見る
Cross-sectional studies have revealed that bone mass is reduced in patients with chronic obstructive pulmonary disease (COPD). To elucidate the factors influencing bone mass in COPD, we measured whole body bone mineral content (BMC) by dual energy X-ray absorptiometry (DXA), pulmonary function, and twelve-minute walking distance (TMD) in men with COPD, who had been monitored for at least one year. We studied the body composition in 22 male patients with COPD and 19 age-matched male controls (age 72.6 ± 7.2 vs 67.5 ± 10.1 years, mean ± SD). COPD patients showed a significantly lower body weight (49.3 ± 5.7 vs 57.9 ± 3.5 kg, respectively), body mass index (18.9 ± 2.1 vs 22.1 ± 1.3 kg/m2) and BMC (1.9 ± 0.4 vs 2.2 ± 0.4 kg) than controls. The changes in BMC were significantly correlated with TMD (r=0.53, p<0.02). These results demonstrate that decreased exercise capacity, at least in part, accounts for acceleration of bone mass loss in COPD patients.(Internal Medicine 36: 450-453, 1997)
- 社団法人 日本内科学会の論文
著者
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Yokoyama Mitsuhiro
Department Of Internal Medicine Division Of Cardiovascular Medicine Kobe University Graduate School
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Yokoyama Mitsuhiro
First Department Of Internal Medicine Kobe University School Of Medicine
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Yokoyama Mitsuhiro
The First Department of Internal Medicine, Kobe University School of Medicine
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Yokoyama Mitsuhiro
Kobe University Graduate School Of Medicine
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Nakata Hiroyuki
Division Of Respiratory Disease Takatsuki General Hospital
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Nakamura Hirofumi
Division Of Respiratory Disease Takatsuki General Hospital
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Yokoyama Mitsuhiro
The First Department Of In Internal Medicine Kobe University School Of Medicine
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Tsutsumi Masaharu
The Department Of Medicine Takatsuki General Hospital
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Maeda Hitoshi
First Department Of Internal Medicine Kobe University School Of Medicine
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NAKATA Hiroyuki
The Department of Respiratory Disease, Takatsuki General Hospital
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MAEDA Hitoshi
The First Department of Internal Medicine, Kobe University School of Medicine
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NISHIMURA Yoshihiro
the Department of Medicine, Takatsuki General Hospital
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Nishimura Yoshihiro
Division Of Respiratory Medicine Department Of Internal Medicine Kobe University Graduate School Of
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Maeda Hitoshi
The First Department Of In Internal Medicine Kobe University School Of Medicine
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Nishimura Yoshihiro
The Department Of Medicine Takatsuki General Hospital
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Nishimura Yoshihiro
Division Of Respiratory Disease Takatsuki General Hospital
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