Cardiovascular Events in Pregnancy With Hypertrophic Cardiomyopathy
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概要
- 論文の詳細を見る
Background:The influence of the physiological circulatory changes during pregnancy on hypertrophic cardiomyopathy (HCM) is unclear. There have been no comprehensive studies of pregnant women with HCM in the Japanese population.Methods and Results:A total of 27 pregnancies (23 women with HCM) were retrospectively reviewed. A total of 18 cardiovascular events occurred in 13 of the 27 pregnancies (48%), and 13 of these events (76%) were related to arrhythmia. The cardiovascular events tended to occur in the early stage of pregnancy (≈30 gestational weeks) or postpartum. The events related to arrhythmia mainly occurred in the early stage of pregnancy or at approximately 30 gestational weeks. Four pregnancies were terminated because of cardiovascular events. Cardiovascular events occurred in 8 of 9 pregnancies in women on medication before pregnancy (88%), 7 of 10 pregnancies with high CARPREG score (70%), and in 9 of 12 pregnancies with high ZAHARA score (75%).Conclusions:Cardiovascular events occurred in more than half of the pregnant women complicated with HCM, and the arrhythmia is the most common cardiovascular event. Medication in the pre-pregnancy period, and CARPREG or ZAHARA score ≥1 were identified as risk factors of cardiac events during pregnancy or postpartum.
- 一般社団法人 日本循環器学会の論文
著者
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Kamiya Chizuko
Department Of Medicine National Cardiovascular Center
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Yoshimatsu Jun
Department Of Obstetrics & Gynecology Oita Medical University
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Iwanaga Naoko
Department Of Obstetrics And Gynecology National Cardiovascular Center
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Tanaka Kayo
Department Of Oral Anatomy Meikai University School Of Dentistry
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Tsuritani Mitsuhiro
Department Of Obstetric And Gynecology Kinki University Faculty Of Medicine
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Yoshida Masashi
Department Of Agricultural Biochemistry And Biotechnology Tottori University
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Tanaka Hiroaki
Department Of Biology Aichi University Of Education
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Neki Reiko
Department Of Perinatology And Gynecology National Cerebral And Cardiovascular Center
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MIYOSHI Takekazu
Department of Perinatology and Gynecology, National Cerebral and Cardiovascular Center
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IKEDA Tomoaki
Deparartment of Perinatology, National Cardiovascular Center
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KATSURAGI Shinji
Deparartment of Perinatology, National Cardiovascular Center
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Kamiya Chizuko
Department of Perinatology, National Cerebral and Cardiovascular Center
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