Long-Term Outcome After Percutaneous Peripheral Intervention vs Medical Treatment for Patients With Superficial Femoral Artery Occlusive Disease
スポンサーリンク
概要
- 論文の詳細を見る
Background Percutaneous peripheral intervention (PPI) for superficial femoral artery (SFA) stenosis is associated with a high restenosis rate. Whether PPI improves the long-term outcome of patients with SFA occlusive disease remains to be determined. Methods and Results A review was done of 107 patients with SFA occlusive disease. Fifty-five patients received PPI for SFA (ie, PPI group) and 52 patients received conservative medical therapy (ie, control group). Clinical records were searched for adverse events (eg, death, limb amputation, re-hospitalization, new onset of coronary artery disease and cerebrovascular disease) for an average of 30.6±17.7 months. At follow-up, only 5 patients (9.1%) in the PPI group experienced improved limb symptoms compared with baseline, and 6 patients (10.9%) showed ischemic skin ulcer or gangrene. In addition, 2 of these 6 patients were unsuccessful PPI cases complicated with distal embolizatjon and perforation. In the control group, 3 patients (5.8%) presented with improved limb symptoms, and an equal number of patients had worsening of symptoms. Although 2 patients showed ischemic skin ulcers at follow-up, both patients had these lesions at baseline. Adverse events were ob-served more frequently in the PPI group than the control group (69.1% vs 46.2%, p<0.05). This was mainly due to a higher frequency of re-hospitalization in the PPI group than in controls (52.7% vs 15.4%, p<0.001). Conclusions The current study demonstrates that PPI for patients with SFA occlusive disease does not provide superior long-term benefits compared with conservative medical therapy, and that medical therapy will continue to remain the primary treatment strategy for this group of patients.
- 社団法人日本循環器学会の論文
- 2008-04-20
著者
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YOSHIMUTA Tsuyoshi
Department of Cardiology, National Cardiovascular Center
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TAKESHITA Satoshi
Department of Cardiology, National Cardiovascular Center
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Yoshimuta Tsuyoshi
Department Of Cardiovascular Medicine National Cardiovascular Center
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Higashi Masahiro
Department Of Cardiovascular Surgery National Cardiovascular Center
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Takeshita Satoshi
Department Of Cardiology
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Akutsu Koichi
Department of Cardiology, National Cardiovascular Center
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Tanaka Ryoichi
Department of Radiology, National cardiovascular center
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Akutsu Koichi
Department Of Cardiovascular Medicine National Cardiovascular Center
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Higashi Masahiro
National Cardiovascular Center
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Yoshimuta Tsuyoshi
Department Of Cardiology National Cardiovascular Center
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Tamori Yuiichi
Department of Cardiovascular medicine, National Cardiovascular Center
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Sakamoto Shingo
Department of Caridovascular Medicine, National Cardiovascular Center
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Higashi Masahiro
Department Of Radiology National Cardiovascular Center
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Sakamoto Shingo
Department Of Cardiovascular Medicine National Cardiovascular Center
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Kamiya Chizuko
Department Of Perinatology National Cardiovascular Center
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Kamiya Chizuko
Department Of Medicine National Cardiovascular Center
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Tamori Yuiichi
Department Of Cardiovascular Medicine National Cardiovascular Center
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Tamori Yuiichi
Department Of Cardiology International Medical Center Of Japan
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Takeshita Satoshi
Department Of Cardiovascular Medicine Department Of Cardiovascular Surgery
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Tanaka Ryoichi
Department Of Botany Faculty Of Science Kyoto University
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Matsuda Hitoshi
Department Of Cardiovascular Surgery National Cardiovascular Center
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Higashi Masahiro
Department Of Cardiovascular Medicine Kyoto Prefectural University Of Medicine
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Takeshita Satoshi
National Cardiovascular Center Research Institute
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Tanaka Ryoichi
Department Of Biomolecular Engineering Graduate School Of Bioscience And Biotechnology Tokyo Institu
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Tanaka Ryoichi
Department of Allergy and Rheumatology, The University of Tokyo Hospital, Japan
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