Crystal Structure of Eucaryotic E3, Lipoamide Dehydrogenase from Yeast.
スポンサーリンク
概要
- 論文の詳細を見る
The crystal structure of eucaryotic lipoamide dehydrogenase from yeast has been determined by an X-ray analysis at 2.7 (partially at 2.4) Å resolution. The enzyme has two identical subunits related by a pseudo twofold symmetry. The tertiary structure is similar to those of other procaryotic enzymes. The active site, consisting of PAD, Cys44, and Cys49 from one subunit and His457' from the other subunit, is highly conserved. This enzyme is directly bound to the core protein E2 of the 2-oxoglutarate dehydrogenase complex, whereas it is bound to the pyruvate dehydrogenase complex through a protein X. The calculated electrostatic potential suggests two characteristic regions for binding with these two proteins.
- 社団法人 日本生化学会の論文
著者
-
Toyoda Tomohiko
Department Of Adult Congenital Heart Disease And Pediatric Cardiology Chiba Cardiovascular Center
-
Takenaka Akio
Department Of Life Science Faculty Of Bioscience And Biotechnology Tokyo Institute Of Tdechnology
-
Reed Lester
Biochemical Institute The University Of Texas At Austin
-
Sekiguchi Takeshi
Department Of Agricultural Chemistry Faculty Of Agriculture Tohoku University
-
Suzuki Kaoru
Department Of Applied Chemistry Faculty Of Science Science University Of Tokyo
関連論文
- Effects of Oxygen and Substrate Temperature on Properties of Amorphous Carbon Films Fabricated by Plasma-Assisted Pulsed Laser Deposition Method
- Cytokine Therapy has Beneficial Effects on Cardiac Remodeling and Vascular Density after Acute Myocardial Infarction in Swine (Vasoactive Compound/Growth Factor/Cytokine 2 (H), The 69th Annual Scientific Meeting of the Japanese Circulation Society)
- OJ-482 G-CSF Prevents Cardiac Remodeling after Acute Myocardial Infarction in Swine(Old Myocardial Infarction/Remodeling 1 (IHD) : OJ59)(Oral Presentation (Japanese))
- Preparation of New Nitrogen-Bridged Heterocycles 67. Syntheses of α,α′-Bis[(thieno[3,4-b]indolizin-3-yl)thio]-o-, m-, and p-xylene Derivatives and Their Conformational Structures
- Nationwide Survey of Care Facilities for Adults With Congenital Heart Disease in Japan
- PE-065 Prevalence of Adult Patients with Congenital Heart Disease in Japan(PE011,Congenital Heart Disease (M),Poster Session (English),The 73rd Annual Scientific Meeting of The Japanese Circulation Society)
- 5 Perspective of Specialized Facilities for Adult Congenital Heart Disease : Analysis from International Survey of Tertiary Care Centers(Patient Menagement System for Adult Congenital Heart Disease,Symposium 19 (SY-19) (M),The 73rd Annual Scientific Meeti
- PJ-776 Psychological Problems of Adults with Congenital Heart Disease(PJ130,Congenital Heart Disease/Kawasaki's Disease (M),Poster Session (Japanese),The 73rd Annual Scientific Meeting of The Japanese Circulation Society)
- OE-415 Nationwide Survey of Care Facilities for Adults with Congenital Heart Disease(Congenital heart disease/Kawasaki's disease(01)(M),Oral Presentation(English),The 72nd Annual Scientific Meeting of the Japanese Circulation Society)
- The Effect of Protozoa on the Composition of Rumen Bacteria in Cattle Using 16S rRNA Gene Clone Libraries
- Difference in Structure of the Gene Encoding H^+-ATPase between Streptococcus bovis and Ruminococcus albus
- Difference in Structure of the Gene Encoding H^+-ATPase between Streptococcus bovis and Ruminococcus albus
- A-19 配列特異的SSU rRNA切断法を用いたウシルーメン細菌叢の定量的解析(ルーメン・消化管生態系,口頭発表)
- Molecular cloning, nucleotide sequence and characteristics of a xylanase gene (xynA) from Ruminococcus albus 7
- ルーメンプロトゾアが子牛の血漿ガストリン濃度に及ぼす影響
- Inhibitory effects of isoleucine and antagonism of the other branched-chain amino acids on fermentation parameters by mixed ruminal microbes in batch cultures and rumen simulating fermenters (Rusitec )
- Effects of amino nitrogen on fermentation parameters by mixed ruminal microbes when energy or nitrogen is limited
- ルーメン細菌叢に及ぼすプロトゾアの影響の分子生物学的手法による解析
- ルーメンプロトゾアの繊維分解酵素とその遺伝子解析
- Fiber Digestion by Rumen Ciliate Protozoa
- ル-メン内窒素代謝と生産性(6)窒素化合物の消化とル-メンプロトゾア
- ル-メンプロトゾアの機能と意義-7-プロトゾア構成とル-メン発酵および細菌叢との関係
- PE-227 Can Pulsed Tissue Doppler Imaging Provide Prognostic Information in Patients with Chronic Pulmonary Thromboembolism?(Echo/Doppler-10, The 71st Annual Scientific Meeting of the Japanese Circulation Society)
- Mental Stress Reduces Coronary Flow Velocity Reserve
- Usefulness of Myoglobin Level Measured by Cardiac Reader^ as a Marker of Impaired Coronary Flow in Unstable Angina
- X-ray Phase-Contrast Imaging and X-ray Absorption Fine Structure Analysis using Parametric X-ray Radiation Generated at LEBRA, Nihon University
- NDFと脂肪含有量に富む食品製造副産物の給与が泌乳前期の乳生産に及ぼす影響
- Diurnal Variation in Coronary Flow Velocity Reserve in Healthy Men
- Estimation of Elevated Brain Natriuretic Peptides by Pulsed Doppler Tissue Imaging in Patients with Pulmonary Hypertension(Pulmonary Circulation 1 (H), The 69th Annual Scientific Meeting of the Japanese Circulation Society)
- PJ-796 Evaluation of Right Ventricular Dysfunction by Strain Echocardiography in Patients with Pulmonary Hypertension Due to Chronic pulmonary Thromboembolism(Pulmonary circulation-4 (H) PJ140,Poster Session (Japanese),The 70th Anniversary Annual Scientif
- PJ-151 Angiotensin-Converting Enzyme Inhibitor Decreases Serum Levels of Asymmetric Dimethylarginine in Patients With Diabetes Mellitus Through a Reduction of Oxidative Stress(Endothelium/NO 3 (H) : PJ26)(Poster Session (Japanese))
- PJ-127 Angiotensinll Type1 Receptor Blocker Candesartan Cilexetil Reduces Serum Levels of Malondialdehyde-Modified Low Density Lipoprotein(Hypertension, Clinical 3 (H) : PJ21)(Poster Session (Japanese))
- PE-121 Assessment of Regional Myocardial Strain by A Novel Automated Tracking System from Digital Image Files(Echo/Doppler 5 (I) : PE21)(Poster Session (English))
- OJ-270 Noninvasive Coronary Flow Reserve Measurements with Transthoracic Doppler Echocardiography as a Screening Test for Coronary Artery Disease(Echo/Doppler 10 (I) : OJ32)(Oral Presentation (Japanese))
- Acute Effect of Cibenzoline on Impaired Coronary Flow Reserve in Patients with Hypertrophic Obstructive Cardiomyopathy
- Angiotensin-Converting Enzyme Inhibitors Improves Coronary Flow Reserve in Type 2 Diabetes Mellitus Related to a Nitric Oxide Synthase Pathway
- Crystal Structure of Eucaryotic E3, Lipoamide Dehydrogenase from Yeast^1
- Crystallization of Eukaryotic E3, Lipoamide Dehydrogenase, from Yeast, for Exhibiting X-Ray Diffraction beyond 2.5 A Resolution, and Preliminary Structure Analysis
- ル-メンプロトゾアの機能と意義-8-宿主に対するプロトゾアの機能
- Platinum-Catalyzed Bis-Germylation of Alkynes with Organodigermanes and Cyclic Oligogermanes
- Pulse-Spray Thrombolysis in Acute Myocardial Infarction Caused by Thrombotic Occlusion of an Ectatic Coronary Artery
- A Case of Vasospastic Angina Presenting Brugada-Type ECG Abnormalities
- A Note on the Surprisal Analysis of Molecular Fragments Produced in a Two-Step Dissociation
- SURGICAL TREATMENT OF RENAL CELL CARCINOMA EXTENDING INTO THE VENA CAVA
- Usefulness of Rapid Quantitative Measurement of Myoglobin and Troponin T in Early Diagnosis of Acute Myocardial Infarction
- Oral Vitamin C restores impaired Coronary Flow Reserve in Smokers
- Circadian Variation in Coronary Flow Reserve is disappeared in Coronary Heart Disease
- OE-234 Impact of Genetic Variation of the Adiponectin Gene and Body Fat Distribution on Development of Atherosclerosis in Metabolic Subjects(Metabolism/Biochemistry/Energetics(01)(M),Oral Presentation(English),The 72nd Annual Scientific Meeting of the Jap
- Crystallographic Studies on Damaged DNAs : III. N^4-Methoxycytosine Can Form Both Watson-Crick Type and Wobbled Base Pairs in a B-Form Duplex^1
- Structural Composition of Hammerhead Ribozymes
- Assessment of the Regional Myocardial Alternations in the Coronary Distal Embolism by Intramyocardial Variability in Integrated Backscatter
- Occasional Hyperglycemia for 75g Oral Glucose Tolerance TestReduces Coronary Flow Velocity Reserve in the Left Anterior Descending Coronary Artery
- Shoshin Beriberi With Vasospastic Angina Pectoris : Possible Mechanism of Mid-Ventricular Obstruction
- Left Ventricular Free Wall Rupture in Acute Fulminant Myocarditis During Long-Term Cardiopulmonary Support
- 0521 Increased QTc dispersion in patients with ventricular fibrillation in chronic phase of acute myocardial infarction
- Myxoma of the kidney
- Prediction of the response to beta-blocker therapy in patients with dilated cardiomyopathy: comparison of 123I-MIBG scintigraphy and low-dose dobutamine stress echocardiography
- Crystal Structure of 3-Isopropylmalate Dehydrogenase from the Moderate Facultative Thermophile, Bacillus coagulans: Two Strategies for Thermostabilization of Protein Structures
- 酵母発酵培養物の添加が乳蛋白質生産,ル-メン発酵および血液性状に及ぼす影響
- A Novel Catalyst System, Antimony(V) Chloride-Lithium Perchlorate(SbCl_5-LiClO_4), in the Friedel-Crafts Acylation Reaction
- L^-theory of noncausal stochastic integrals
- Insights into the Structures of DNA Damaged by Hydroxyl Radical: Crystal Structures of DNA Duplexes Containing 5-Formyluracil
- Preparation of Binuclear Octaethylporphinatoruthenium(II) Complexes Bridged with Diaza Compounds and Their Electrochemical Oxidation
- Overexpression of Heat Shock Factor 1 Masks the Heavy Metal Response of the Heat Shock Protein 70 (hsp70) Gene Promoter
- DIFFERENTIAL DISPLAY ANALYSIS OF GENES EXPRESSED IN THE FOREBRAIN OF ANDROGENIZED FEMALE NEONATAL RATS
- Stimulated Emission of Excitonic Molecule in CuBr
- Stimulated Emission of Excitonic Molecule in CuCl Single Crystals
- Inhibition of Metallothionein Induction by Ultraviolet Light Irradiation (Proceedings of the 20th Symposium on Toxicology and Environmental Health)
- A Hamster Temperature-Sensitive Alanyl-tRNA Synthetase Mutant Causes Degradation of Cell-Cycle Related Proteins and Apoptosis
- A Temperature-Sensitive Mutant of the Mammalian RNA Helicase, DEAD-BOXX Isoform, DBX, Defective in the Transition from G1 to S Phase
- Dialyzability of the Antiepileptic Drug Zonisamide in Patients Undergoing Hemodialysis
- A remark on L^∞ in the space of BMO-martingales
- SYNTHESIS OF 3-O-α-D-GLCOPYRANOSYL-D-GLUCOSE (SAKEBIOSE OR NIGEROSE) I. REACTION OF 1, 2-5, 6-DI-O-ISOPROPYLIDENE-D-GLUCOFURANOSE AND 2, 3, 4, 6-TETRA-O-ACETYL-α-D-GLUCOPYRANOSYL BROMIDE
- An Efficient Synthesis of Unsymmetrical Sulfides from Organic Disulfides and Aromatic Compounds
- An Efficient Catalytic Friedel-Crafts Acylation Reaction of Equimolar Amounts of Aromatic Compounds and Free Carboxylic Acids or Their Trimethylsilylesters via Mixed Anhydrides
- Palladium-Catalyzed Addition of Tetragermetanes to Alkynes
- 高エネルギー飼料給与時におけるホルスタイン種育成雌牛の発育および窒素出納に及ぼす飼料中粗タンパク質および第一胃非分解性タンパク質含量の影響
- Actinohivin : specific amino acid residues essential for anti-HIV activity
- Remarks on a criterion for the uniform integrability of positive local martingales
- Effects of Casein and Soy-Protein on .ALPHA.-Linolenic Acid Metabolism in Rats.
- Fecal Output, Gastrointestinal Transit Time, Frequency of Evacuation and Apparent Excretion Rate of Dietary Fiber in Young Men Given Diets Containing Different Levels of Dietary Fiber.
- Emission spectra of CH(A2.DELTA.) produced from CH3CN in the argon flowing-afterglow reaction.
- Formation of CN(B2.SIGMA.+) in the reaction of acetonitrile with metastable Ar(3P2,0) atoms.
- Crystal Structure of Eucaryotic E3, Lipoamide Dehydrogenase from Yeast.
- A Temperature-Sensitive Mutant of the Mammalian RNA Helicase, DEAD-BOX X Isoform, DBX, Defective in the Transition from G 1 to S Phase