Hypolipidemic Effects of Starch and γ-Oryzanol from wx/ae Double-Mutant Rice on BALB/c.KOR-Apoeshl Mice
スポンサーリンク
概要
- 論文の詳細を見る
waxy/amylose-extender (wx/ae) double-mutant japonica rice (Oryza sativa L.) produces resistant starch (RS) and a large amount of γ-oryzanol. Our previous study has shown the hypolipidemic effect of wx/ae brown rice on mice. To identify the functional constituents of the hypolipidemic activity in wx/ae rice, we prepared pure wx/ae starch and γ-oryzanol from wx/ae rice and investigated their effect on the lipid metabolism in BALB/c.KOR/Stm Slc-Apoeshl mice. The mice were fed for 3 weeks a diet containing non-mutant rice starch, non-mutant rice starch plus γ-oryzanol, wx/ae starch, or wx/ae starch plus γ-oryzanol. γ-Oryzanol by itself had no effect on the lipid metabolism, and wx/ae starch prevented an accumulation of triacylglycerol (TAG) in the liver. Interestingly, the combination of wx/ae starch plus γ-oryzanol not only prevented a TAG accumulation in the liver, but also partially suppressed the rise in plasma TAG concentration, indicating that wx/ae starch and γ-oryzanol could have a synergistic effect on the lipid metabolism.
著者
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Hirai Hiroaki
Graduate School Of Life And Environmental Sciences Osaka Prefecture University
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Shojo Aiko
Graduate School For International Development And Cooperation Hiroshima University
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Kitamura Shinichi
Graduate School Of Agriculture And Biological Sciences Osaka Prefecture University
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Matsumoto Kenji
Department Of Allergy And Immunology National Institute For Child Health & Development
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Hirai Hiroaki
Graduate School of Life and Environmental Sciences, Osaka Prefecture University
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NAKAYA Makoto
Graduate School of Life and Environmental Sciences, Osaka Prefecture University
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MATSUMOTO Kenji
Department of Food Science, Ishikawa Prefectural University
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Matsumoto Kenji
Department of Allergy & Immunology, National Research Institute for Child Health and Development
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