Comparison of Glucose Fluctuations between Day- and Night-Time Measured Using a Continuous Glucose Monitoring System in Diabetic Dogs
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概要
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Monitoring of blood glucose concentration is important to evaluate the diabetic status of dogs. Continuous glucose monitoring systems (CGMS) have been applied in veterinary medicine for glucose monitoring in diabetic dogs. The purpose of the study was to evaluate the daily glycemic profiles obtained with CGMS and compare glucose fluctuations between day- and night-time in diabetic dogs. Five diabetic dogs were used in this study and were treated with either NPH insulin or insulin detemir. For data analyses, day-time was defined as 9:00am–9:00pm and night-time as 9:00pm–9:00am. Using glucose profiles, we determined the mean glucose concentrations (1- and 12-hr intervals), and times spent in hyperglycemia >200 mg/dl or hypoglycemia 60 mg/dil/i. None of the parameters differed significantly between day-time and night-time in dogs treated with NPH insulin or insulin detemir. In conclusion, this study confirmed, using CGMS, that there are no differences in glucose fluctuations between day- and night-time, in diabetic dogs on a similar feeding regimen and insulin administration.br
著者
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Mori Akihiro
Department Of Electric Engineering Faculty Of Engineering Kyoto University
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ODA Hitomi
Department of Veterinary Nursing and Technology, Nippon Veterinary and Life Science University
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KURISHIMA Miyuki
Department of Veterinary Nursing & Technology, School of Veterinary Science, Nippon Veterinary and Life Science University, 1–7–1 Kyonancho, Musashino, Tokyo 180–8602, Japan
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SAKO Toshinori
Department of Veterinary Nursing & Technology, School of Veterinary Science, Nippon Veterinary and Life Science University, 1–7–1 Kyonancho, Musashino, Tokyo 180–8602, Japan
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ARAI Toshiro
Department of Biochemistry, Nippon Veterinary and Animal Science University, 1-7-1 Kyonan-cho, Musashino-shi, Tokyo 180-8602, Japan
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SAEKI Kaori
Department of Veterinary Nursing & Technology, School of Veterinary Science, Nippon Veterinary and Life Science University, 1–7–1 Kyonancho, Musashino, Tokyo 180–8602, Japan
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Oda Hitomi
Department of Chemistry, Faculty of Science, Kwansei Gakuin University
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ODA Hitomi
Department of Veterinary Nursing & Technology, School of Veterinary Science, Nippon Veterinary and Life Science University, 1–7–1 Kyonancho, Musashino, Tokyo 180–8602, Japan
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