Impact of Commercially Available Diabetic Prescription Diets on Short-Term Post-Prandial Serum Glucose, Insulin, Triglyceride and Free Fatty Acid Concentrations of Obese Cats
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概要
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Diet therapy is an important treatment component available for obese cats. In this study, the impact of four commercially available prescription diet regimens [1 for general use and 3 aimed at treating obesity and diabetes mellitus (DM)] on short-term post-prandial serum glucose, insulin, triglyceride and non-esterified fatty acid (NEFA) concentrations was investigated with five obese cats. The diet regimens used were as follows: C/D dry (general use: moderate protein, moderate fat, high carbohydrate and low fiber); M/D dry (DM: high protein, high fat, low carbohydrate and high fiber); W/D dry (DM: high protein, low fat, high carbohydrate and high fiber); and Diabetic dry (DM: high protein, low fat, low carbohydrate and high fiber). A significant reduction (10–13%) in postprandial glucose (area under the curve; AUC) was observed with the M/D and Diabetic diets, which both contained lower concentrations of carbohydrates than the C/D diet. An accompanying significant reduction (30–36%) in postprandial insulin AUC was also observed with the three DM diets, which all had higher amounts of fiber, as compared with the C/D diet. Lastly, a significant increase (32–65%) in postprandial NEFA AUC was observed with the M/D and Diabetic diets as compared with the C/D diet. Therefore, dietary amounts of carbohydrates and fiber, as opposed to protein content or dietary fat, appear to have a very significant impact on post-prandial glycemia and subsequent insulin requirement levels in obese cats. In addition, dietary amounts of carbohydrate may also impact lipid metabolism in obese cats.
著者
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SAKO Toshinori
Department of Veterinary Nursing, School of Veterinary Nursing and Technology, Nippon Veterinary and
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Mori Akihiro
Department Of Electric Engineering Faculty Of Engineering Kyoto University
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Arai Toshiro
Department Of Veterinary Biochemistry
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Lee Peter
Department Of Materials Imperial College
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ODA Hitomi
Department of Veterinary Nursing and Technology, Nippon Veterinary and Life Science University
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SAEKI Kaori
Department of Veterinary Nursing and Technology, Nippon Veterinary and Life Science University
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UEDA Kaori
Department of Veterinary Nursing and Technology, School of Veterinary Science, Nippon Veterinary and Life Science University, 1–7–1 Kyonancho, Musashino, Tokyo 180–8602, Japan
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Ueda Kaori
Department of Industrial Chemistry, Faculty of Engineering, Nagasaki University
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MIMURA Kana
Department of Veterinary Nursing and Technology, School of Veterinary Science, Nippon Veterinary and Life Science University, 1–7–1 Kyonancho, Musashino, Tokyo 180–8602, Japan
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SAKO Toshinori
Department of Veterinary Nursing & Technology, School of Veterinary Science, Nippon Veterinary and Life Science University, 1–7–1 Kyonancho, Musashino, Tokyo 180–8602, Japan
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ARAI Toshiro
Department of Veterinary Medicine, School of Veterinary Science, Nippon Veterinary and Life Science University, 1–7–1 Kyonancho, Musashino, Tokyo 180–8602, Japan
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ARAI Toshiro
Department of Biochemistry, Nippon Veterinary and Animal Science University, 1-7-1 Kyonan-cho, Musashino-shi, Tokyo 180-8602, Japan
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SAEKI Kaori
Department of Veterinary Nursing & Technology, School of Veterinary Science, Nippon Veterinary and Life Science University, 1–7–1 Kyonancho, Musashino, Tokyo 180–8602, Japan
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MORI Akihiro
Department of Veterinary Nursing and Technology, School of Veterinary Science, Nippon Veterinary and Life Science University, 1–7–1 Kyonancho, Musashino, Tokyo 180–8602, Japan
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Oda Hitomi
Department of Chemistry, Faculty of Science, Kwansei Gakuin University
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